K Baran, E Preston, D Wilks, GJ Cooney, EW Kraegen, … - Diabetes, 2002 - Am Diabetes Assoc Increased hypothalamic neuropeptide-Y (NPY) action and disruption of the melanocortin
(MC)-4 receptor both result in hyperphagia and obesity. To determine whether similar hormonal
and metabolic mechanisms are involved in these two obesity syndromes, we investigated ... Cited by 34 - Related articles - BL Direct - All 4 versions
PJ Currie, DV Coscina - Peptides, 1995 - ncbi.nlm.nih.gov The present study investigated the effects of neuropeptide Y (NPY) on food intake and body temperature
(Tbo) in free-feeding unrestrained rats following injection into the medial hypothalamic paraventricular
nucleus (PVN) or the lateral perifornical hypothalamus (PFH). NPY (78-235 pmol) or ... Cited by 45 - Related articles - All 2 versions
- ►ebmonline.org T Yasuda, T Masaki, T Kakuma, H Yoshimatsu - Experimental Biology and …, 2004 - SEBM To clarify the neuronal mechanism of the hypothalamic melanocortin system in regulating energy
metabolism, we investigated the effects of centrally administered -melanocyte-stimulating hormone
( -MSH) and agouti-related protein (AGRP), an agonist and an antagonist for the ... Cited by 33 - Related articles - BL Direct - All 5 versions
CJ Small, MS Kim, SA Stanley, JRD Mitchell, K Murphy, … - Diabetes, 2001 - Am Diabetes Assoc The melanocortin receptor (MC3-R and MC4-R) antagonist, agouti-related protein (AGRP), is
a potent stimulant of food intake. We examined the effect of chronic intracerebroventricular
(ICV) AGRP treatment on energy metabolism and pituitary function in ad libitum fed rats ... Cited by 95 - Related articles - BL Direct - All 4 versions
FB Jolicoeur, SM Bouali, A Fournier, S St-Pierre - Brain research bulletin, 1995 - Elsevier The objective of the present study was to identify hypothalamic sites that might be implicated
in the effects of neuropeptide Y (NPY) on both body temperature and food intake. For this
purpose, the effects of direct microinjections of NPY in several doses (0.156–20 μg) into ... Cited by 37 - Related articles - BL Direct - All 4 versions
Z Szreder, T Hori, Y Kaizuka - General pharmacology, 1994 - ncbi.nlm.nih.gov 1. In order to characterize the thermoregulatory actions of brain neuropeptide Y (NPY), the effects
of intra-third ventricular (I3V) injection of NPY on temperatures of colon (Tco), brown adipose
tissue (TBAT) and tail skin (Ts) were observed at ambient temperatures (Ta) of 19 and 8 ... Cited by 10 - Related articles - BL Direct - All 2 versions
BS Hamilton, HN Doods - Obesity, 2002 - nature.com Research Methods and Procedures: Ex-breeder Chbb:Thom rats (350 to 400 g) were divided
into two groups: highly palatable food (HPF) and normal rat chow (RC). Both groups had ab libitum
access to rat chow. The HPF group had access to chocolate bars, cookies, cheese, and ... Cited by 33 - Related articles - BL Direct - All 4 versions
A Kask, R Pähkla, A Irs, L Rägo, JES Wikberg, HB … - Neuroreport, 1999 - journals.lww.com IN this study we investigated the long term effects of a potent and selective melanocortin 4 (MC
4 ) receptor antagonist (HS014) on food intake, body weight, body composition and blood glucose
levels in adult rats. HS014 was injected icv either by twice-daily injections (2 × 1 nmol) for ... Cited by 52 - Related articles - BL Direct - All 3 versions
[CITATION] Chronic CNS administration of agouti-related protein reduces energy expenditure
CJ Small, YL Liu, SA Stanley, IP Connoley, A Kennedy, … - Int Obes Relat Disord, 2003 Cited by 2 - Related articles
- ►endojournals.org C Fekete, S Sarkar, WM Rand, JW Harney, CH … - Endocrinology, 2002 - Endocrine Soc Because -MSH has a potent stimulatory action on hypophysiotropic TRH synthesizing neurons
in the hypothalamic paraventricular nucleus (PVN), preventing the effects of fasting on the gene
expression of the TRH prohormone (proTRH), we hypothesized that agouti-related ... Cited by 57 - Related articles - BL Direct - All 4 versions
