KM Gillespie, EAM Gale, PJ Bingley - Diabetes, 2002 - Am Diabetes Assoc Early onset type 1 diabetes is associated with rapid β-cell failure and high levels of HLA-mediated
genetic susceptibility. We examined familial risk of disease in relation to age at onset in 1,299
families participating in the Bart's Oxford population-based family study of type 1 diabetes. ... Cited by 42 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org AK Steck, KJ Barriga, LM Emery, RV Fiallo-Scharer, … - Diabetes care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We analyzed family histories of 1,586 patients in Colorado
with type 1 diabetes (83% non-Hispanic white, 10% Hispanic, and 7% other) diagnosed before
16 years of age and interviewed during 1999–2002. Families of probands with type 2, ... Cited by 10 - Related articles - All 5 versions
V Harjutsalo, T Podar, J Tuomilehto - Diabetes, 2005 - Am Diabetes Assoc The aims of our analysis were to obtain the empirical risk estimates for type 1 diabetes in the
siblings of a Finnish population-based cohort of childhood-onset diabetic patients and search
for demographic and other factors predicting the risk of type 1 diabetes in siblings. We ... Cited by 22 - Related articles - All 6 versions
T Lorenzen, F Pociot, L Stilgren, OP Kristiansen, J … - Diabetologia, 1998 - Springer Insulin-dependent diabetes mellitus (IDDM) is a se- rious chronic disorder caused by an immune
mediat- ed selective destruction of the insulin-producing beta cells in the pancreas.
Genetically, IDDM is a complex disorder. In previous studies the average rate of IDDM ... Cited by 32 - Related articles - BL Direct - All 3 versions
[CITATION] Study Group and The Eurodiab Ace Substudy 2 Study Group Familial risk of type I …
- ►diabetesjournals.org M Kukko, SM Virtanen, A Toivonen, S Simell, S … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—The high- and moderate-risk genotypes were unevenly distributed among the three
areas (P < 0.001); the high-risk genotype was less frequent in the Oulu region (20.4%) than in
the Turku (28.4%; P < 0.001) or Tampere regions (27.2%; P < 0.001). This genotype was ... Cited by 20 - Related articles - BL Direct - All 7 versions
SW Guo, J Tuomilehto - Genetic epidemiology, 2002 - interscience.wiley.com It has been widely reported that men with type 1 diabetes (T1D) tend to be more likely to transmit
the disease to their offspring than their female counterparts in Caucasoid populations. Several
theories to explain this preferential transmission have been proposed, but so far none of ... Cited by 10 - Related articles - BL Direct - All 4 versions
T Lorenzen, F Pociot, P Hougaard, J Nerup - Diabetologia, 1994 - Springer Summary Due to a short observation period previous studies may have underestimated prevalence
and re- currence risk of IDDM in relatives of IDDM patients. To obtain a more exact life-time risk
estimate we iden- tified 310 probands, representative of Danish IDDM patients, ... Cited by 74 - Related articles - BL Direct - All 3 versions