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Scholar Results 1 - 10 of about 101 related to Gillespie: High familial risk and genetic susceptibility in early onset childhood diabetes. (0.15 sec) 

High familial risk and genetic susceptibility in early onset childhood diabetes


KM Gillespie, EAM Gale, PJ Bingley - Diabetes, 2002 - Am Diabetes Assoc
Early onset type 1 diabetes is associated with rapid β-cell failure and high levels of HLA-mediated
genetic susceptibility. We examined familial risk of disease in relation to age at onset in 1,299
families participating in the Bart's Oxford population-based family study of type 1 diabetes. ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Secondary attack rate of type 1 diabetes in Colorado families

- diabetesjournals.org
AK Steck, KJ Barriga, LM Emery, RV Fiallo-Scharer, … - Diabetes care, 2005 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—We analyzed family histories of 1,586 patients in Colorado
with type 1 diabetes (83% non-Hispanic white, 10% Hispanic, and 7% other) diagnosed before
16 years of age and interviewed during 1999–2002. Families of probands with type 2, ...
Cited by 10 - Related articles - All 5 versions

Factors modifying the risk of IDDM in offspring of an IDDM parent.


M El-Hashimy, MC Angelico, BC Martin, AS Krolewski, … - Diabetes, 1995 - Am Diabetes Assoc
Cited by 25 - Related articles - BL Direct - All 4 versions

Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset …


V Harjutsalo, T Podar, J Tuomilehto - Diabetes, 2005 - Am Diabetes Assoc
The aims of our analysis were to obtain the empirical risk estimates for type 1 diabetes in the
siblings of a Finnish population-based cohort of childhood-onset diabetic patients and search
for demographic and other factors predicting the risk of type 1 diabetes in siblings. We ...
Cited by 22 - Related articles - All 6 versions

Predictors of IDDM recurrence risk in offspring of Danish IDDM patients


T Lorenzen, F Pociot, L Stilgren, OP Kristiansen, J … - Diabetologia, 1998 - Springer
Insulin-dependent diabetes mellitus (IDDM) is a se- rious chronic disorder caused by an immune
mediat- ed selective destruction of the insulin-producing beta cells in the pancreas.
Genetically, IDDM is a complex disorder. In previous studies the average rate of IDDM ...
Cited by 32 - Related articles - BL Direct - All 3 versions

[CITATION] Study Group and The Eurodiab Ace Substudy 2 Study Group Familial risk of type I …


ACE Eurodiab - Diabetologia, 1998
Cited by 9 - Related articles

Geographical variation in risk HLA-DQB1 genotypes for type 1 diabetes and signs …

- diabetesjournals.org
M Kukko, SM Virtanen, A Toivonen, S Simell, S … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—The high- and moderate-risk genotypes were unevenly distributed among the three
areas (P < 0.001); the high-risk genotype was less frequent in the Oulu region (20.4%) than in
the Turku (28.4%; P < 0.001) or Tampere regions (27.2%; P < 0.001). This genotype was ...
Cited by 20 - Related articles - BL Direct - All 7 versions

Preferential transmission of type 1 diabetes from parents to offspring: fact or artifact …


SW Guo, J Tuomilehto - Genetic epidemiology, 2002 - interscience.wiley.com
It has been widely reported that men with type 1 diabetes (T1D) tend to be more likely to transmit
the disease to their offspring than their female counterparts in Caucasoid populations. Several
theories to explain this preferential transmission have been proposed, but so far none of ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Long-term risk of IDDM in first-degree relatives of patients with IDDM


T Lorenzen, F Pociot, P Hougaard, J Nerup - Diabetologia, 1994 - Springer
Summary Due to a short observation period previous studies may have underestimated prevalence
and re- currence risk of IDDM in relatives of IDDM patients. To obtain a more exact life-time risk
estimate we iden- tified 310 probands, representative of Danish IDDM patients, ...
Cited by 74 - Related articles - BL Direct - All 3 versions

Risk of diabetes in siblings and other relatives of IDDM subjects.


C Allen, M Palta, DJ D'Alessio - Diabetes, 1991 - Am Diabetes Assoc
Cited by 35 - Related articles - All 4 versions


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