- ►diabetesjournals.org M Biarnés, M Montolio, V Nacher, M Raurell, … - Diabetes, 2002 - Am Diabetes Assoc We studied the effects of hyperglycemia on β-cell death and mass in
syngeneically transplanted islets. Six groups of STZ-induced diabetic C57BL/6
mice were transplanted with 100 syngeneic islets, an insufficient β-cell ... Cited by 114 - Related articles - BL Direct - All 6 versions
AM Davalli, L Scaglia, DH Zangen, J Hollister … - Diabetes, 1996 - Am Diabetes Assoc To learn more about islet vulnerability in the immediate posttransplant period,
400 syngeneic islets were transplanted under the kidney capsule of B6AF1 mice.
Three groups of recipients were used: normal mice (normal), streptozotocin ... Cited by 237 - Related articles - BL Direct - All 5 versions
PO Carlsson, F Palm, A Andersson, P Liss - Diabetes, 2001 - Am Diabetes Assoc In this study, we syngeneically transplanted islets to three different
implantation sites of diabetic and nondiabetic rats, then 9–12 weeks later we
measured the blood perfusion and compared the tissue partial pressure of ... Cited by 106 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] E Montana, S Bonner-Weir, GC Weir - Journal of Clinical Investigation, 1993 - pubmedcentral.nih.gov In islet transplantation, nonimmunological factors such as lim- ited growth
capacity or increased death rate could reduce the beta cell mass in the graft
and lead to failure of the transplant. We studied the evolution of beta ... Cited by 107 - Related articles - BL Direct - All 6 versions
- ►endojournals.org PO Carlsson, F Palm, G Mattsson - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Pancreatic islets are avascular immediately after transplantation. Although the
islets are rapidly revascularized, it is uncertain whether the revascularization
produces an adequate oxygenation of the transplanted islet tissue. We ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►jleukbio.org NR Barshes, S Wyllie, JA Goss - Journal of leukocyte biology, 2005 - Soc Leukocyte Biology Recent advances in clinical protocols have improved the outcomes of pancreatic
islet transplantation (PIT), yet PIT recipients typically require pancreatic
islet grafts derived from multiple donors to achieve insulin independence. ... Cited by 56 - Related articles - All 8 versions
JF Merino, V Nacher, M Raurell, O Aranda, J … - Diabetologia, 1997 - Springer Islet transplantation is a promising treatment for dia- betes mellitus, but
current results are disappointing [1–4]. A crucial question determining the
outcome of islet transplantation is beta-cell mass. The amount Cited by 18 - Related articles - BL Direct - All 4 versions
F Vargas, M Vives-Pi, N Somoza, P Armengol, L … - Transplantation, 1998 - journals.lww.com Clinical transplantation of human islets has a disappointingly low rate of
success. We report here the identification of a possible causative factor:
endotoxin present in the collagenase preparations used to disperse the ... Cited by 49 - Related articles - BL Direct - All 3 versions
- ►shouxi.net JA Emamaullee, RV Rajotte, P Liston, RG … - Diabetes, 2005 - Am Diabetes Assoc The Edmonton Protocol for treatment of type 1 diabetes requires islets from two
or more donors to achieve euglycemia in a single recipient, primarily because
soon after portal infusion, the majority of the transplanted cells undergo ... Cited by 24 - Related articles - BL Direct - All 8 versions
KE Dionne, CK Colton, ML Yarmush - Diabetes, 1993 - Am Diabetes Assoc The effect of pO2s reduced below physiological levels on GSIR by isolated islets
of Langerhans was investigated with a microperifusion apparatus that provided
control of pO2 and rapid dynamic response. Second-phase insulin secretion ... Cited by 151 - Related articles - BL Direct - All 5 versions
