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Scholar Results 1 - 10 of about 101 related to Persaud: A Key Role for β-Cell Cytosolic Phospholipase A2 in the Maintenance of Insulin.... (0.10 sec) 

A Key Role for β-Cell Cytosolic Phospholipase A2 in the Maintenance of Insulin Stores But Not …


SJ Persaud, HM Roderigo-Milne, PE Squires, … - Diabetes, 2002 - Am Diabetes Assoc
Cytosolic phospholipase A 2 (cPLA 2 ) is a Ca 2+ -sensitive enzyme that has been
implicated in insulin secretion in response to agents that elevate β-cell
intracellular Ca 2+ ([Ca 2+ ] i ). We generated clones of the MIN6 β-cell ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Identification and localisation of a type IV cytosolic phospholipase A2 in rat pancreatic {beta} …


KJ Parker, PM Jones, CH Hunton, SJ Persaud, … - Journal of molecular endocrinology, 1996 - Soc Endocrinology
The liberation of arachidonic acid (AA), by phospholipase A 2 (PLA 2 ), is the
rate-limiting step in a number of cell signalling pathways. In the pancreatic
β-cell, AA itself is thought to participate in the regulation of insulin ...
Cited by 23 - Related articles - BL Direct - All 6 versions

[CITATION] Identification of cytosolic PLA 2 isoforms in human and rat pancreatic islets and insulin- …


M Chen, ZD Yang, A Naji, BA Wolf - Endocrinology, 1996
Cited by 6 - Related articles

The role of cytosolic phospholipase A2 in insulin secretion


PM Jones, CJ Burns, VD Belin, HM Roderigo- … - Diabetes, 2004 - Am Diabetes Assoc
Cytosolic phospholipase A 2 (cPLA 2 ) comprises a widely expressed family of
enzymes, some members of which have the properties required of signal
transduction elements in electrically excitable cells. Thus, α- and ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Phospholipase A2 expression in human and rodent insulin-secreting cells


AC Loweth, JHB Scarpello, NG Morgan - Molecular and cellular endocrinology, 1995 - Elsevier
The expression of different isoforms of phospholipase A 2 in human and rat
islets of Langerhans and in the clonal B-cell lines, HIT_T15 and RINm5F has been
investigated, using polyclonal antisera specific to human cytosolic (cPLA 2 ...
Cited by 19 - Related articles - All 5 versions

Transient activation of calcium-dependent phospholipase A2 by insulin secretagogues in …


YC Jolly, C Major, BA Wolf - Biochemistry, 1993 - pubs.acs.org
Transient Activation of Calcium-Dependent Phospholipase A2 by Insulin ... Y.
Camille Jolly, Christopher Major, and Bryan A. Wolf ... Department of Pathology
and Laboratory Medicine. University of Pennsylvania School of Medicine, ...
Cited by 31 - Related articles - BL Direct - All 4 versions

[CITATION] Arachidonic acid is a second messenger in nutrient-induced insulin secretion from rat …


PM Jones, SJ Persaud - J Endocrinol, 1993
Cited by 6 - Related articles

[CITATION] Pancreatic islet phospholipase A2: differential, Ca2+-dependent effects of lysophospholipids …


SA Metz - Adv Prostaglandin Thromboxane Leukot Res, 1987 - grande.nal.usda.gov
Title: Pancreatic islet phospholipase A2: differential, Ca2+-dependent effects
of lysophospholipids, arachidonic acid, and its lipoxygenase-derived metabolites
on insulin release. Author: Metz, SA Citation: ...
Cited by 9 - Related articles - Cached - All 2 versions

cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for …

- physiology.org
K Juhl, M Høy, HL Olsen, K Bokvist, AM … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
Using capacitance measurements, we investigated the effects of intracellularly
applied recombinant human cytosolic phospholipase A 2 (cPLA 2 ) and its
lipolytic products arachidonic acid and lysophosphatidylcholine on Ca 2 + - ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Glucose-induced regulation of COX-2 expression in human islets of Langerhans


SJ Persaud, CJ Burns, VD Belin, PM Jones - Diabetes, 2004 - Am Diabetes Assoc
Cyclo-oxygenase (COX), the enzyme responsible for conversion of arachidonic acid
to prostanoids, exists as two isoforms. In most tissues, COX-1 is a constitutive
enzyme involved in prostaglandin-mediated physiological processes, whereas ...
Cited by 11 - Related articles - BL Direct - All 5 versions


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