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Scholar Results 1 - 10 of about 101 related to Uehara: Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-bindi.... (0.13 sec) 

Polyunsaturated fatty acids and acetoacetate downregulate the expression of the …

- diabetesjournals.org
Y Uehara, T Engel, Z Li, C Goepfert, S Rust, X Zhou, C … - Diabetes, 2002 - Am Diabetes Assoc
Low HDL cholesterol is a frequent cardiovascular risk factor in diabetes. Because of its pivotal
role for the regulation of HDL plasma levels, we investigated in vivo and in vitro regulation of
the ATP-binding cassette transporter A1 (ABCA1) by insulin and metabolites ...
Cited by 56 - Related articles - BL Direct - All 6 versions

Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing …

- jbc.org
Y Wang, JF Oram - Journal of Biological Chemistry, 2002 - ASBMB
Abnormal high density lipoprotein metabolism may contribute to the increased atherosclerosis
associated with diabetes and insulin resistance. The ATP-binding cassette transporter ABCA1
mediates cholesterol transport from tissue macrophages to apoA-I, the major high density ...
Cited by 140 - Related articles - BL Direct - All 5 versions

Unsaturated fatty acids suppress the expression of the ATP-binding cassette …


Y Uehara, S Miura, A von Eckardstein, S Abe, A Fujii, Y … - Atherosclerosis, 2007 - Elsevier
ATP-binding cassette transporters (ABC) G1 and ABCA1 are membrane cholesterol transporters
and have been implicated to mediate cholesterol efflux from cells in the presence of high density
lipoproteins and its major protein constituent apolipoprotein AI, respectively. We ...
Cited by 27 - Related articles - All 15 versions

Leukocyte ABCA1 gene expression is associated with fasting glucose …


C Albrecht, I Simon-Vermot, JI Elliott, CF Higgins, DG … - Metabolism, 2004 - Elsevier
Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) mediates the efflux of
cholesterol to apolipoprotein A1, a process necessary for high-density lipoprotein (HDL) formation
and reverse cholesterol transport. In patients with Tangier disease, mutations in ABCA1 ...
Cited by 29 - Related articles - All 9 versions

Advanced glycation end product precursors impair ABCA1-dependent cholesterol …

- diabetesjournals.org
M Passarelli, C Tang, TO McDonald, KD O'Brien, RG … - Diabetes, 2005 - Am Diabetes Assoc
Abnormal HDL metabolism may contribute to the increased atherosclerosis associated with
diabetes. The ATP-binding cassette transporter A1 (ABCA1) is an atheroprotective cell protein
that mediates cholesterol transport from cells to apolipoprotein (apo) AI, the major protein ...
Cited by 34 - Related articles - All 5 versions

LXR-mediated activation of macrophage stearoyl-CoA desaturase generates …

- jlr.org
Y Wang, B Kurdi-Haidar, JF Oram - The Journal of Lipid Research, 2004 - ASBMB
Abnormal HDL metabolism among patients with diabetes and insulin resistance may contribute
to their increased risk of atherosclerosis. ATP binding cassette transporter A1 (ABCA1) mediates
the transport of cholesterol and phospholipids from cells to HDL apolipoproteins and thus ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a …

- jbc.org
Y Wang, JF Oram - Journal of Biological Chemistry, 2005 - ASBMB
Abnormal high density lipoprotein (HDL) metabolism among patients with diabetes and insulin
resistance may contribute to their increased risk of atherosclerosis. ATP-binding cassette transporter
ABCA1 mediates the transport of cholesterol and phospholipids from cells to HDL ...
Cited by 34 - Related articles - BL Direct - All 4 versions

Statins downregulate ATP-binding-cassette transporter A1 gene expression in …


H Sone, H Shimano, M Shu, M Nakakuki, A … - … and Biophysical Research …, 2004 - Elsevier
The ATP-binding-cassette transporter A1 (ABCA1) plays an essential role in cellular cholesterol
efflux and helps prevent macrophages from becoming foam cells. The statins are widely used
as cholesterol-lowering agents and have other anti-atherogenic actions. We tested the ...
Cited by 39 - Related articles - All 4 versions

[CITATION] LXR-mediated increase in ABCA1 expression is attenuated by fatty acids in CaCo2 …


S Murthy, E Born, SN Mathur, FJ Field - Biochem. J, 2004
Cited by 4 - Related articles

Reduction in ABCG1 in type 2 diabetic mice increases macrophage foam cell …

- jbc.org
JP Mauldin, S Srinivasan, A Mulya, A Gebre, JS … - Journal of Biological …, 2006 - ASBMB
Atherosclerosis development is accelerated severalfold in patients with Type 2 diabetes. In the
initial stages of disease, monocytes transmigrate into the subendothelial space and differentiate
into foam cells. Scavenger receptors and ATP binding cassette (ABC) Transporters play ...
Cited by 22 - Related articles - BL Direct - All 6 versions


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