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Scholar Results 1 - 10 of about 101 related to Zhang: Tumor necrosis factor-α stimulates lipolysis in differentiated human adipocytes through.... (0.14 sec) 

Tumor necrosis factor-α stimulates lipolysis in differentiated human adipocytes …


HH Zhang, M Halbleib, F Ahmad, VC Manganiello, AS … - Diabetes, 2002 - Am Diabetes Assoc
Tumor necrosis factor-α (TNF-α) stimulates lipolysis in human adipocytes. However, the mechanisms
regulating this process are largely unknown. We demonstrate that TNF-α increases lipolysis
in differentiated human adipocytes by activation of mitogen-activated protein kinase ...
Cited by 137 - Related articles - BL Direct - All 6 versions

Mapping of early signaling events in tumor necrosis factor-alpha-mediated lipolysis …


M Ryden, A Dicker, V van Harmelen, H Hauner, M … - Journal of Biological …, 2002 - ASBMB
Tumor necrosis factor- (TNF- ) is a pleiotropic cytokine with a proposed role in obesity-related
insulin resistance. This could be mediated by increased lipolysis in adipose tissue resulting in
elevated free fatty acid levels. The early intracellular signals entailed in TNF- -mediated ...
Cited by 113 - Related articles - BL Direct - All 5 versions

Tumor necrosis factor increases the rate of lipolysis in primary cultures of …


A Green, SB Dobias, DJ Walters, AR Brasier - Endocrinology, 1994 - Endocrine Soc
ABSTRACT To investigate the effects of cytokines on adipocyte lipolysis, a macrophage cell
line (RAW 264.7) was treated with Escherichia coli lipopolysaccharide (1 rg/ml) for 18 h to induce
cytokine release. Con- ditioned medium (5%, vol/vol) from these cells was added to rat ...
Cited by 103 - Related articles - BL Direct - All 3 versions

TNF-a induction of lipolysis is mediated through activation of the extracellular …


SC Souza, HJ Palmer, YH Kang, MT … - Journal of Cellular …, 2003 - interscience.wiley.com
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Cited by 70 - Related articles - BL Direct - All 3 versions

Tumor necrosis factor alpha stimulates lipolysis in adipocytes by decreasing Gi …

- jbc.org
S Gasic, B Tian, A Green - Journal of Biological Chemistry, 1999 - ASBMB
Prolonged treatment (12-24 h) of adipocytes with tumor necrosis factor (TNF ) stimulates
lipolysis. We have investigated the hypothesis that TNF stimulates lipolysis by blocking the action
of endogenous adenosine. Adipocytes were incubated for 48 h with TNF , and lipolysis ...
Cited by 93 - Related articles - BL Direct - All 5 versions

Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha …

- jbc.org
SC Souza, LM de Vargas, MT Yamamoto, P Lien, … - Journal of Biological …, 1998 - ASBMB
Perilipins, a family of phosphoproteins, are specifically located at the surface of intracellular lipid
(triacylglycerol) droplets, the site of lipolysis. Stimulation of lipolysis in 3T3-L1 adipocytes by
tumor necrosis factor (TNF- ) is associated with a decrease in total cellular expression of ...
Cited by 193 - Related articles - BL Direct - All 4 versions

Targets for TNF-α-induced lipolysis in human adipocytes


M Rydén, E Arvidsson, L Blomqvist, L Perbeck, A … - … and Biophysical Research …, 2004 - Elsevier
Background. Tumor necrosis factor-α (TNF-α)-induced lipolysis may be important for insulin resistance
in both obesity and cachexia. In rodent cells TNF-α enhances lipolysis through down-regulation
of the expression of the membrane proteins Gα i and the lipid droplet-associated protein ...
Cited by 64 - Related articles - All 6 versions

Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal- …

- jbc.org
AS Greenberg, WJ Shen, K Muliro, S Patel, SC … - Journal of Biological …, 2001 - ASBMB
Hormonally stimulated lipolysis occurs by activation of cyclic AMP-dependent protein kinase
(PKA) which phosphorylates hormone-sensitive lipase (HSL) and increases adipocyte
lipolysis. Evidence suggests that catecholamines not only can activate PKA, but also the ...
Cited by 136 - Related articles - BL Direct - All 4 versions

Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes …

- nih.gov [PDF] 
TR Landström, J Mei, M Karlsson, V … - Biochemical …, 2000 - pubmedcentral.nih.gov
We have used murine 3T3-L1 cells, which differentiate in culture and acquire morphological
and biochemical features of mature adipocytes, as a model for studying the expression of
cyclic- nucleotide phosphodiesterase (PDE) 3B activity, protein and mRNA during ...
Cited by 49 - Related articles - BL Direct - All 4 versions

[CITATION] TNF-α induction of lipolysis is mediated through activation of the extracellular …


SC Souza - Journal of Cellular Biochemistry, 2003 - Wiley Subscription Services, Inc., A …
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