ML Standaert, HK Ortmeyer, MP Sajan, Y Kanoh, G … - Diabetes, 2002 - Am Diabetes Assoc Rhesus monkeys frequently develop obesity and insulin resistance followed by type 2 diabetes
when allowed free access to chow. This insulin resistance is partly due to defective glucose transport
into skeletal muscle. In this study, we examined signaling factors required for insulin- ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►endojournals.org Y Kanoh, G Bandyopadhyay, MP Sajan, ML Standaert, … - Endocrinology, 2001 - Endocrine Soc Atypical protein kinases C (PKCs), and , and protein kinase B (PKB) are thought to function downstream
of phosphatidylinositol 3-kinase (PI 3-kinase) and regulate glucose transport during insulin action
in skeletal muscle and adipocytes. Insulin-stimulated glucose transport is defective in type ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►endojournals.org Y Kanoh, MP Sajan, G Bandyopadhyay, A Miura, ML … - Endocrinology, 2003 - Endocrine Soc Insulin-stimulated glucose transport in skeletal muscle is thought to be effected at least partly
through atypical protein kinase C isoforms (aPKCs) operating downstream of phosphatidylinositol
(PI) 3-kinase and 3-phosphoinositide-dependent protein kinase-1 (PDK-1). However, ... Cited by 30 - Related articles - BL Direct - All 3 versions
YB Kim, K Kotani, TP Ciaraldi, RR Henry, BB Kahn - Diabetes, 2003 - Am Diabetes Assoc In humans with obesity or type 2 diabetes, insulin target tissues are resistant to many actions
of insulin. The atypical protein kinase C (PKC) isoforms λ and ζ are downstream of
phosphatidylinositol-3 kinase (PI3K) and are required for maximal insulin stimulation of ... Cited by 79 - Related articles - BL Direct - All 5 versions
M Beeson, MP Sajan, M Dizon, D Grebenev, J Gomez- … - Diabetes, 2003 - Am Diabetes Assoc Insulin resistance in type 2 diabetes is partly due to impaired glucose transport in skeletal
muscle. Atypical protein kinase C (aPKC) and protein kinase B (PKB), operating downstream
of phosphatidylinositol (PI) 3-kinase and its lipid product, PI-3,4,5-(PO 4 ) 3 (PIP 3 ), ... Cited by 90 - Related articles - BL Direct - All 4 versions
- ►endojournals.org MP Sajan, ML Standaert, A Miura, G … - Journal of Clinical …, 2004 - Endocrine Soc Insulin resistance in obesity is partly due to diminished glucose transport in myocytes and
adipocytes, but underlying mechanisms are uncertain. Insulin-stimulated glucose transport requires
activation of phosphatidylinositol (PI) 3-kinase (3K), operating downstream of insulin ... Cited by 15 - Related articles - BL Direct - All 4 versions
G Bandyopadhyay, MP Sajan, Y Kanoh, ML … - Journal of Biological …, 2001 - ASBMB Insulin controls glucose uptake by translocating GLUT4 and other glucose transporters to the
plasma membrane in muscle and adipose tissues by a mechanism that appears to require protein
kinase C (PKC)-ζ/λ operating downstream of phosphatidylinositol 3-kinase. In diabetes ... Cited by 46 - Related articles - BL Direct - All 6 versions
A Miura, Y Kanoh, J Powe, G Bandyopadhyay, ML … - DIABETES, 2003 - Am Diabetes Assoc Page 1. Activation of Protein Kinase C- by Insulin and Phosphatidylinositol-3,4,5-(
PO 4 ) 3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance
Amelioration by Rosiglitazone and Exercise Mary Beeson ... Related articles
[CITATION] Acción fisiológica de la insulina
PJ Flakoll, MG Carlson, AD Cherrington, D Le Roith, SI … - … y Clínica. 2ª ed. México: Mc …, 2003 Cited by 6 - Related articles
- ►endojournals.org G Bandyopadhyay, Y Kanoh, MP Sajan, ML Standaert, … - Endocrinology, 2000 - Endocrine Soc We used adenoviral gene transfer methods to evaluate the role of atypical protein kinase Cs
(PKCs) during insulin stimulation of glucose transport in L6 myotubes. Expression of wild-type
PKC- potentiated maximal and half-maximal effects of insulin on 2-deoxyglucose uptake, ... Cited by 79 - Related articles - BL Direct - All 2 versions
