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Scholar Results 1 - 10 of about 101 related to Tan: Role of NADH shuttles in glucose-induced insulin secretion from fetal β-cells. (0.09 sec) 

Role of NADH shuttles in glucose-induced insulin secretion from fetal β-cells

- diabetesjournals.org
C Tan, BE Tuch, J Tu, SA Brown - Diabetes, 2002 - Am Diabetes Assoc
The NADH shuttle system, which transports the substrate for oxidative metabolism
directly from the cytosol to the mitochondrial electron transport chain, has
been shown to be essential for glucose-induced activation of mitochondrial ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Evidence of enhancement of malate-aspartate shuttle activity in β cells of streptozotocin- …


DK Song, YH Ahn, JH Bae, WK Park, YS … - Metabolism, 2000 - Elsevier
Glucose-induced insulin secretion is selectively impaired in β cells from
animals with non—insulin-dependent diabetes mellitus (NIDDM). This study was
performed to clarify whether the malate-aspartate shuttle among the glucose ...
Cited by 4 - Related articles - BL Direct - All 8 versions

Expression of glucokinase in glucose-unresponsive human fetal pancreatic islet-like cell …

- endojournals.org
J Tu, BE Tuch - Journal of Clinical Endocrinology & Metabolism, 1997 - Endocrine Soc
Glucokinase (GK) is the glucose sensor in the adult ß-cell, resulting in fuel
for insulin synthesis and secretion. Defects in this enzyme in the ß-cell are
responsible for the genetic disorder maturity-onset diabetes of the young, ...
Cited by 6 - Related articles - BL Direct - All 6 versions

[PDF] The importance of redox shuttles to pancreatic beta-cell energy metabolism and function


K Bender, P Newsholme, L Brennan, P … - Biochemical Society Transactions, 2006 - biochemsoctrans.org
Introduction The significance of redox shuttle mechanisms has been extens- ively
described in brain, smooth muscle and cardiac tissue [1– 3]. However, recent
research has revealed their presence and importance to energy metabolism in ...
Cited by 8 - Related articles - View as HTML - BL Direct - All 4 versions

Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH


MJ MacDonald, PC Kelley, M Laclau - Metabolism, 2002 - Elsevier
The activity of lactate dehydrogenase is known to be low in the pancreatic [beta
] cell, and the activity of the mitochondrial glycerol phosphate dehydrogenase
(mGPD), the key enzyme of the glycerol phosphate shuttle, is known to be ...
Cited by 9 - Related articles - BL Direct - All 6 versions

Enzymes in pancreatic islets that use NADP (H) as a cofactor including evidence for …


M Laclau, F Lu, MJ MacDonald - Molecular and Cellular Biochemistry, 2001 - Springer
Page 1. 151 Molecular and Cellular Biochemistry 225: 151–160, 2001. © 2001
Kluwer Academic Publishers. Printed in the Netherlands. ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Modulação dos Mecanismos de Defesa das Ilhotas Pancreáticas Contra o Estresse …


LF Stoppiglia, AC Boschero, AC Boschero, SAB …, 2006 - libdigi.unicamp.br
Page 1. UNIVERSIDADE ESTADUAL DE CAMPINAS Luiz Fabrizio Stoppiglia Modulação dos
Mecanismos de Defesa das Ilhotas Pancreáticas Contra o Estresse Oxidativo ...
Related articles - All 3 versions

The export of metabolites from mitochondria and anaplerosis in insulin secretion


MJ MacDonald - BBA-General Subjects, 2003 - Elsevier
Combinations of insulin secretagogue-derived metabolites were added to microgram
amounts of mitochondria obtained from rat and mouse pancreatic islets and the
INS-1 cell line, and the export of citric acid cycle intermediates was ...
Cited by 25 - Related articles - All 6 versions

The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, …

- jbc.org
B Rubi, A del Arco, C Bartley, J Satrustegui, … - Journal of Biological Chemistry, 2004 - ASBMB
The NADH shuttle system, which transports reducing equivalents from the cytosol
to the mitochondria, is essential for the coupling of glucose metabolism to
insulin secretion in pancreatic beta cells. Aralar1 and citrin are two ...
Cited by 28 - Related articles - All 6 versions

NADH shuttle and insulin secretion


A Schurr… - Science, 2000 - sciencemag.org
In their report (1), Eto et al. hypothesize that nicotinamide adenine
dinucleotide (NADH) is the signal for the coupling of glycolytic and
mitochondrial glucose metabolism that triggers insulin secretion. Their ...
Cited by 1 - Related articles - All 2 versions


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