- ►diabetesjournals.org C Tan, BE Tuch, J Tu, SA Brown - Diabetes, 2002 - Am Diabetes Assoc The NADH shuttle system, which transports the substrate for oxidative metabolism
directly from the cytosol to the mitochondrial electron transport chain, has
been shown to be essential for glucose-induced activation of mitochondrial ... Cited by 12 - Related articles - BL Direct - All 5 versions
DK Song, YH Ahn, JH Bae, WK Park, YS … - Metabolism, 2000 - Elsevier Glucose-induced insulin secretion is selectively impaired in β cells from
animals with non—insulin-dependent diabetes mellitus (NIDDM). This study was
performed to clarify whether the malate-aspartate shuttle among the glucose ... Cited by 4 - Related articles - BL Direct - All 8 versions
- ►endojournals.org J Tu, BE Tuch - Journal of Clinical Endocrinology & Metabolism, 1997 - Endocrine Soc Glucokinase (GK) is the glucose sensor in the adult ß-cell, resulting in fuel
for insulin synthesis and secretion. Defects in this enzyme in the ß-cell are
responsible for the genetic disorder maturity-onset diabetes of the young, ... Cited by 6 - Related articles - BL Direct - All 6 versions
K Bender, P Newsholme, L Brennan, P … - Biochemical Society Transactions, 2006 - biochemsoctrans.org Introduction The significance of redox shuttle mechanisms has been extens- ively
described in brain, smooth muscle and cardiac tissue [1– 3]. However, recent
research has revealed their presence and importance to energy metabolism in ... Cited by 8 - Related articles - View as HTML - BL Direct - All 4 versions
MJ MacDonald, PC Kelley, M Laclau - Metabolism, 2002 - Elsevier The activity of lactate dehydrogenase is known to be low in the pancreatic [beta
] cell, and the activity of the mitochondrial glycerol phosphate dehydrogenase
(mGPD), the key enzyme of the glycerol phosphate shuttle, is known to be ... Cited by 9 - Related articles - BL Direct - All 6 versions
LF Stoppiglia, AC Boschero, AC Boschero, SAB …, 2006 - libdigi.unicamp.br Page 1. UNIVERSIDADE ESTADUAL DE CAMPINAS Luiz Fabrizio Stoppiglia Modulação dos
Mecanismos de Defesa das Ilhotas Pancreáticas Contra o Estresse Oxidativo ... Related articles - All 3 versions
MJ MacDonald - BBA-General Subjects, 2003 - Elsevier Combinations of insulin secretagogue-derived metabolites were added to microgram
amounts of mitochondria obtained from rat and mouse pancreatic islets and the
INS-1 cell line, and the export of citric acid cycle intermediates was ... Cited by 25 - Related articles - All 6 versions
- ►jbc.org B Rubi, A del Arco, C Bartley, J Satrustegui, … - Journal of Biological Chemistry, 2004 - ASBMB The NADH shuttle system, which transports reducing equivalents from the cytosol
to the mitochondria, is essential for the coupling of glucose metabolism to
insulin secretion in pancreatic beta cells. Aralar1 and citrin are two ... Cited by 28 - Related articles - All 6 versions
A Schurr… - Science, 2000 - sciencemag.org In their report (1), Eto et al. hypothesize that nicotinamide adenine
dinucleotide (NADH) is the signal for the coupling of glycolytic and
mitochondrial glucose metabolism that triggers insulin secretion. Their ... Cited by 1 - Related articles - All 2 versions