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Scholar Results 1 - 10 of about 101 related to Zagon: Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in.... (0.09 sec) 

Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat


IS Zagon, JB Jenkins, JW Sassani, JD Wylie, … - Diabetes, 2002 - Am Diabetes Assoc
Ulcers and erosions of the corneal epithelium, as well as delays in resurfacing
of the cornea after wounding, are major causes of ocular morbidity and visual
loss in diabetes. To study whether intervention by the opioid antagonist ...
Cited by 24 - Related articles - BL Direct - All 5 versions

Re-epithelialization of the rat cornea is accelerated by blockade of opioid receptors


IS Zagon, JW Sassani, PJ McLaughlin - Brain research, 1998 - cat.inist.fr
A native opioid peptide,[Met 5 ]-enkephalin, termed opioid growth
factor(OGF), serves as a constitutively expressed and autocrine produced
inhibitory molecule related to developing, neoplastic, renewing, and ...
Cited by 23 - Related articles - All 4 versions

Reepithelialization of the human cornea is regulated by endogenous opioids

- iovs.org
IS Zagon, JW Sassani, PJ McLaughlin - Investigative ophthalmology & visual science, 2000 - ARVO
METHODS. Eight-millimeter-diameter epithelial defects were created with a
trephine and mechanical scraping in the center of human corneas. Resurfacing was
studied in organ culture. The size of the defect, the number of specimens ...
Cited by 33 - Related articles - BL Direct - All 5 versions

Topically applied naltrexone restores corneal reepithelialization in diabetic rats


MS Klocek, JW Sassani, PJ McLaughlin, IS … - Journal of Ocular Pharmacology and Therapeutics, 2007 - liebertonline.com
MATTHEW S. KLOCEK, 1 JOSEPH W. SASSANI, 2 ... PATRICIA J. M C LAUGHLIN, 1 and
IAN S. ZAGON 1 ... Purpose: Complications of diabetes include an increased risk
of delayed corneal epithelial wound healing. This study examined the ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Corneal safety of topically applied naltrexone


IS Zagon, MS Klocek, JW Sassani, DT Mauger … - Journal of Ocular Pharmacology & Therapeutics, 2006 - liebertonline.com
IAN S. ZAGON, 1 MATTHEW S. KLOCEK, 1 JOSEPH W. SASSANI, 2 DAVID T. MAUGER, 3
... Purpose: Naltrexone (NTX), an opioid antagonist, accelerates wound healing
of corneal ep- ithelium in normal and diabetic animals. This study examined ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Insulin treatment ameliorates impaired corneal reepithelialization in diabetic rats

- diabetesjournals.org
IS Zagon, JW Sassani, PJ McLaughlin - Diabetes, 2006 - Am Diabetes Assoc
Patients with diabetes are at an increased risk for developing corneal
disorders, often as a result of surgical and nonsurgical trauma. This study
investigated whether intensive treatment of diabetes with the goal of ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Prevention of diabetic keratopathy

- bmj.com [PDF] 
Y Kaji - British Medical Journal, 2005 - bjo.bmj.com
I n this issue of the BJO (p 261), Siddiqui et al review the compliance of
researchers with quality standards for evaluations of diagnostic test perfor-
mance (DTP). ''Standards'' were origin- ally set by the McMaster evidence ...
Cited by 16 - Related articles - All 8 versions

Fibronectin facilitates corneal epithelial wound healing in diabetic rats


M NAKAMURA, N SATO, TAII CHIKAMA, Y … - Experimental eye research, 1997 - Elsevier
To determine whether the effect of fibronectin on corneal epithelial healing
occurs in eyes affected by diabetes, the effect of fibronectin on the rates at
which corneal epithelial wounds healed was compared in diabetic and normal ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Glucagon secretory response to hypoglycaemia, adrenaline and carbachol in streptozotocin- …


B Ahren, JS Stern, RL Gingerich, DL Curry, … - Acta Physiologica Scandinavica, 1995 - interscience.wiley.com
Glucagon response to insulin-induced hypoglycaemia is impaired in diabetes, but
the mechanism is not established. Pancreatic A cell hyporesponsiveness to
adrenergic or cholinergic stimulation could contribute to the impairment. ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell …


IS Zagon, JW Sassani, MF Verderame, PJ … - Cornea, 2005 - journals.lww.com
Cornea. Wolters Kluwer Health Logo. All Issues. ...
Cited by 14 - Related articles - BL Direct - All 3 versions


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