V Portik-Dobos, MP Anstadt, J Hutchinson, M Bannan, … - Diabetes, 2002 - Am Diabetes Assoc Pathological remodeling characterized by extracellular matrix (ECM) deposition contributes to
the diabetic vascular complications. Matrix metalloproteinases (MMPs) regulate ECM
turnover. However, the expression profile of the MMP system in diabetic human tissue ... Cited by 78 - Related articles - BL Direct - All 4 versions
JS Mondy, MP Anstadt, DL Franga, V Portik-Dobos, … - ETHNICITY AND …, 2002 - ishib.org The incidence of diabetic amputations is 2- to 3-fold higher in African-American patients compared
to Caucasians. Vascular remodeling characterized by extracellular matrix (ECM) deposition occurs
in diabetes and contributes to vascular complications. The matrix metal- loproteinases ... Cited by 8 - Related articles - View as HTML - BL Direct - All 3 versions
AK Death, EJ Fisher, KCY McGrath, DK Yue - Atherosclerosis, 2003 - Elsevier Diabetes is a major risk factor for atherosclerosis. Hyperglycemia is an underlying contributing
factor; however, the mechanisms that mediate the vascular complications are not yet fully
understood. In the present study, we provide evidence that elevated glucose induces ... Cited by 96 - Related articles - All 12 versions
PR Maxwell, PM Timms, S Chandran, D Gordon - Diabetic Medicine, 2001 - ingentaconnect.com Aim To determine the plasma levels of enzymes and inhibitors involved in extracellular matrix
turnover in patients with Type 1 diabetes with normal renal function. ... Methods Plasma levels
of matrix metalloproteinases 2 and 9 (MMP-2, MMP-9) and tissue inhibitor of ... Cited by 52 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org S Jesmin, I Sakuma, Y Hattori, A … - … , thrombosis, and vascular …, 2003 - Am Heart Assoc Methods and Results— By immunohistochemistry and in situ hybridization, transforming growth
factor-ß 1 (TGF-ß 1 ) expression increased in coronary vessels, the perivascular area, and cardiomyocytes
in diabetic rat hearts. Increased expression of plasminogen activator inhibitor-1 (PAI-1) in ... Cited by 33 - Related articles - BL Direct - All 8 versions
G Derosa, MA Avanzini, D Geroldi, R Fogari, R … - Diabetes research and …, 2005 - Elsevier Thirteen male and 12 female patients were evaluated at the clinical diagnosis and onset of T1DM
and again at a 5-year follow-up. Twelve patients had developed microangiopathic complications
at the follow-up evaluation. MMP-2 and MMP-9 levels and activity were detected in ... Cited by 29 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org SV McLennan, SKY Martell, DK Yue - Diabetes, 2002 - Am Diabetes Assoc High glucose concentrations can decrease degradation of mesangium by reducing the activities
of matrix metalloproteinases (MMPs). The aim of this study was to investigate the effects of glycation
of mesangium matrix on MMP-2, the principal MMP secreted by mesangial cells to ... Cited by 62 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org S Uemura, H Matsushita, W Li, AJ Glassford, T … - Circulation …, 2001 - Am Heart Assoc Abstract—Diabetes mellitus (DM) is a primary risk factor for cardiovascular disease. Although
recent studies have demonstrated an important role for extracellular matrix metalloproteinases
(MMPs) in atherosclerosis, little is known about the effects of hyperglycemia on MMP ... Cited by 222 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org AWY Chung, YN Hsiang, LA Matzke, BM McManus … - Circulation …, 2006 - Am Heart Assoc Impaired angiogenesis could contribute to the increased incidence of coronary and peripheral
artery disease in diabetic patients. Angiogenesis is initiated by vascular endothelial growth factor
(VEGF), a potent angiogenic cytokine, and suppressed by angiostatin, which is generated ... Cited by 40 - Related articles - All 8 versions
M Kuzuya, T Asai, S Kanda, K Maeda, XW Cheng, A … - Diabetologia, 2001 - Springer Page 1. With aging or in diabetes, arteries exhibit increases in media thickness and
wall collagen content with stiff- ening of the vessel wall [1, 2]. The major proposed
mechanisms for the development of arterial stiffness are the ... Cited by 40 - Related articles - BL Direct - All 3 versions
