HP Hammes, J Lin, O Renner, M Shani, A Lundqvist, C … - Diabetes, 2002 - Am Diabetes Assoc Pericytes provide vascular stability and control endothelial proliferation. Pericyte loss,
microaneurysms, and acellular capillaries are characteristic for the diabetic retina. Platelet-derived
growth factor (PDGF)-B is involved in pericyte recruitment, and brain capillaries of mice ... Cited by 179 - Related articles - BL Direct - All 13 versions
M Enge, M Bjarnegård, H Gerhardt, E … - The EMBO …, 2002 - pubmedcentral.nih.gov Loss of pericytes from the capillary wall is a hallmark of diabetic retinopathy, however, the pathogenic
significance of this phenomenon is unclear. In previous mouse gene knockout models leading
to pericyte deficiency, prenatal lethality has so far precluded analysis of postnatal ... Cited by 112 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org HP Hammes, J Lin, P Wagner, Y Feng, F vom Hagen, T … - Diabetes, 2004 - Am Diabetes Assoc Pericyte loss is an early pathologic feature of diabetic retinopathy, consistently present in retinae
of diabetic humans and animals. Because pericyte recruitment and endothelial cell survival are
controlled, in part, by the angiopoietin/Tie2 ligand/receptor system, we studied the ... Cited by 79 - Related articles - BL Direct - All 4 versions
- ►nih.gov A Uemura, M Ogawa, M Hirashima, T … - Journal of Clinical …, 2002 - Am Soc Clin Investig Interactions between endothelial cells (ECs) and perivascular mural cells (MCs) via signaling
molecules or physical contacts are implicated both in vascular remodeling and maintenance
of vascular integrity. However, it remains unclear how MCs regulate the morphogenic ... Cited by 146 - Related articles - BL Direct - All 7 versions
- ►nih.gov M Hellstrom, H Gerhardt, M Kalen, X Li, U … - Journal of Cell …, 2001 - jcb.rupress.org The association of pericytes (PCs) to newly formed blood vessels has been suggested to regulate
endothelial cell (EC) proliferation, survival, migration, differentiation, and vascular
branching. Here, we addressed these issues using PDGF-B– and PDGF receptor-ß ... Cited by 305 - Related articles - BL Direct - All 7 versions
- ►nih.gov [PDF] P Lindblom, H Gerhardt, S Liebner, A … - Genes & …, 2003 - genesdev.cshlp.org Several platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF)
family members display C-terminal protein motifs that confer retention of the secreted factors
within the pericellular space. To address the role of PDGF-B retention in vivo, we deleted ... Cited by 144 - Related articles - BL Direct - All 7 versions
- ►amjpathol.org JL Wilkinson-Berka, S Babic, T de Gooyer, AW Stitt, K … - American Journal of …, 2004 - ASIP We investigated whether inhibition of platelet-derived growth factor (PDGF) receptor tyrosine
kinase activity would affect pericyte viability, vascular endothelial growth factor (VEGF)/vascular
endothelial growth factor receptor-2 (VEGFR-2) expression and angiogenesis in a model ... Cited by 47 - Related articles - BL Direct - All 5 versions
A Tidhar, M Reichenstein, D Cohen, A … - Developmental …, 2001 - interscience.wiley.com A unique pattern of LacZ expression was found in a transgenic mouse line, likely due to regulatory
elements at the site of integration. Two new genes flanking the transgene were identified. At
early stages of development, the transgene is transiently expressed in ventro-lateral ... Cited by 38 - Related articles - BL Direct - All 2 versions
H Gerhardt, C Betsholtz - Cell and tissue research, 2003 - Springer Abstract It takes two to make blood vessels—endothe- lial cells and pericytes. While the endothelial
cells are the better characterized of the two, pericytes are now coming into focus as important
regulators of angiogenesis and blood vessel function, and as potential drug targets. ... Cited by 265 - Related articles - BL Direct - All 4 versions
