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Scholar Results 1 - 10 of about 101 related to van Rossum: A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity.... (0.11 sec) 

A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to …

- eur.nl [PDF] 
EFC van Rossum, JW Koper, NATM Huizenga, … - Diabetes, 2002 - Am Diabetes Assoc
We investigated whether a polymorphism in codons 22 and 23 of the glucocorticoid
(GC) receptor gene [GAGAGG(GluArg) → GAAAAG(GluLys)] is associated with
altered GC sensitivity, anthropometric parameters, cardiovascular risk ...
Cited by 123 - Related articles - BL Direct - All 6 versions

[PDF] Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with …


EFC van Rossum, JW Koper, AW van den Beld, … - Variation in the Glucocorticoid Receptor Gene: …, 2003 - publishing.eur.nl
Identification of the BclI polymorphism 31 Abstract Objective: Sensitivity to
glucocorticoids differs between individuals, partially due to genetic variation
in the glucocorticoid receptor (GR) gene. We studied the sequence ...
Cited by 97 - Related articles - View as HTML - BL Direct - All 6 versions

A polymorphism in the glucocorticoid receptor gene may be associated with an increased …

- endojournals.org
NATM Huizenga, JW Koper, P de Lange, HAP … - Journal of Clinical Endocrinology & Metabolism, 1998 - Endocrine Soc
In a group of 216 elderly persons, 13 heterozygotes for the N363S polymorphism
were identified by PCR/single strand conformation polymorphism analysis. In 2
dexamethasone (DEX) suppression tests (DSTs), using 1 and 0.25 mg DEX, the ...
Cited by 291 - Related articles - BL Direct - All 6 versions

Lack of association between five polymorphisms in the human glucocorticoid receptor gene …


JW Koper, RP Stolk, P de Lange, NATM … - Human genetics, 1997 - Springer
Abstract Glucocorticoid resistance due to mutations in the gene for the
glucocorticoid receptor has been sug- gested to be more common than is thought
at present, ow- ing to the relative mildness of its symptoms and the dif- ...
Cited by 167 - Related articles - BL Direct - All 3 versions

Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival …

- eur.nl [PDF] 
EFC van Rossum, RA Feelders, AW van den … - The American journal of medicine, 2004 - Elsevier
We recently demonstrated that a polymorphism in codons 22 and 23 of the
glucocorticoid receptor gene is associated with relative glucocorticoid
resistance, greater insulin sensitivity, and lower total and low-density ...
Cited by 33 - Related articles - All 11 versions

The N363S polymorphism of the glucocorticoid receptor: potential contribution to central …

- endojournals.org
MG Dobson, CPF Redfern, N Unwin, JU … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
Considerable evidence suggests that diabetes mellitus and hypertension are
influenced by genetic factors. Studies in humans have associated glucocorticoid
receptor (GR) polymorphisms with high blood pressure, insulin sensitivity, ...
Cited by 86 - Related articles - BL Direct - All 4 versions

The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a …

- endojournals.org
EFC van Rossum, PG Voorhoeve, SJ te Velde … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
Glucocorticoids play an important role in determining body composition. A
polymorphism of the glucocorticoid receptor gene (in codons 22 and 23) has
previously been found to be associated with relative glucocorticoid ...
Cited by 59 - Related articles - BL Direct - All 6 versions

Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype

- endojournals.org
A Stevens, DW Ray, E Zeggini, S John, HL … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
ENDOGENOUS GLUCOCORTICOID (GC) production mediates multiple metabolic effects
and increased production is required for a successful stress response. GCs are
potent antiinflammatory drugs used to treat conditions such as rheumatoid ...
Cited by 82 - Related articles - BL Direct - All 6 versions

Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic …


EFC van Rossum, SWJ Lamberts - Recent Progress in Hormone Research, 2004 - Endocrine Soc
Most actions of glucocorticoids (GCs) are mediated by the glucocorticoid
receptor (GR). The interindividual response to GCs varies considerably, as
demonstrated by a variable suppressive response to 0.25-mg dexamethasone ...
Cited by 114 - Related articles - BL Direct - All 2 versions

The relation between two polymorphisms in the glucocorticoid receptor gene and body mass …


AM Di Blasio, EFC van Rossum, S Maestrini, ME … - Clinical Endocrinology, 2003 - interscience.wiley.com
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Cited by 58 - Related articles - BL Direct - All 4 versions


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