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Scholar Results 1 - 10 of about 101 related to Makhlouf: The role of autoimmunity in islet allograft destruction. (0.11 sec) 

The role of autoimmunity in islet allograft destruction


L Makhlouf, K Kishimoto, RN Smith, R Abdi, … - Diabetes, 2002 - Am Diabetes Assoc
Although it has often been assumed that transplanted allogeneic islets can be
destroyed by recurrent autoimmunity in recipients with type 1 diabetes,
definitive evidence is lacking and the settings in which this may occur ...
Cited by 40 - Related articles - BL Direct - All 5 versions

The Role of Autoimmunity in Islet Allograft Destruction


TATCC Blockade - DIABETES, 2002 - Am Diabetes Assoc
Page 1. The Role of Autoimmunity in Islet Allograft Destruction Major
Histocompatibility Complex Class II Matching Is Necessary for ...
Related articles

Allorecognition and effector pathways of islet allograft rejection in normal versus nonobese …

- asnjournals.org
L Makhlouf, A Yamada, T Ito, R Abdi, MJI … - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol
Type I diabetes mellitus is an important cause of end-stage renal disease, and
islet allotransplantation, with or without kidney transplantation, offers a
potential cure for diabetes mellitus (1). Different pathways of ...
Cited by 18 - Related articles - BL Direct - All 4 versions

MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo

- jimmunol.org
TM Kupfer, ML Crawford, K Pham, RG Gill - The Journal of Immunology, 2005 - Am Assoc Immnol
When transplanted into type 1a diabetic recipients, islet allografts are subject
both to conventional allograft immunity and, presumably, to recurrent autoimmune
(islet-specific) pathogenesis. Importantly, CD4 T cells play a central role ...
Cited by 21 - Related articles - All 4 versions

Immunotherapy With Nondepleting Anti-Cd4 Monoclonal Antibodies But Not Cd28 Antagonists …


Z Guo, T Wu, N Kirchhof, D Mital, JW … - Transplantation, 2001 - journals.lww.com
Skip Navigation Links Home > June 15, 2001 - Volume 71 - Issue 11 >
Immunotherapy With Nondepleting Anti-Cd4 Monoclonal Antibodi... ... Guo,
Zhiguang; Wu, Tao; Kirchhof, Nicole; Mital, Deepak; Williams, James W.; ...
Cited by 33 - Related articles - BL Direct - All 4 versions

[PDF] Recurrent Autoimmunity Accelerates Destruction of Minor and Major Histoincompatible …


T Okitsu, ST Bartlett, GA Hadley, CB … - American Journal of Transplantation, 2001 - anesthesia.umm.edu
Recurrent autoimmunity destroys nonobese diabetic (NOD) islet isografts, but
whether recurrent autoim- munity contributes to islet graft destruction in im-
munocompetent allogeneic recipients is unknown. In the NOD, a single dose ...
Cited by 18 - Related articles - View as HTML - All 9 versions

A major role for host MHC class I antigen presentation for promoting islet allograft survival


J Beilke, Z Johnson, N Kuhl, RG Gill - Transplantation proceedings, 2004 - Elsevier
The purpose of this study was to determine the role for CD8 T cells versus
generalized MHC class I–restricted antigen presentation in islet allograft
rejection and tolerance. Diabetic C57BI/6 (B6, H-2 b ) controls, C57BI/6 ...
Cited by 5 - Related articles - All 6 versions

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell …

- diabetesjournals.org
RD Molano, T Berney, H Li, P Cattan, A Pileggi … - Diabetes, 2001 - Am Diabetes Assoc
Allorejection and recurrence of autoimmunity are the major barriers to
transplantation of islets of Langerhans for the cure of type 1 diabetes in
humans. CD40-CD154 (CD40 ligand) interaction blockade by the use of ...
Cited by 76 - Related articles - BL Direct - All 4 versions

NOD mice have a generalized defect in their response to transplantation tolerance induction


TG Markees, DV Serreze, NE Phillips, CH … - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc
A protocol consisting of a single donor-specific trans- fusion (DST) plus a
brief course of anti-CD154 mono- clonal antibody (anti-CD40 ligand mAb) induces
per- manent islet allograft survival in chemically diabetic mice, but its ...
Cited by 79 - Related articles - BL Direct - All 6 versions

Characterization of the role of major histocompatibility complex in type 1 diabetes recurrence …


HY Young, P Zucker, RA Flavell, AM Jevnikar, … - Transplantation, 2004 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 8 - Related articles - All 4 versions


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