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Scholar Results 1 - 10 of about 101 related to Forbes: Reduction of the accumulation of advanced glycation end products by ACE inhibition.... (0.11 sec) 

Reduction of the accumulation of advanced glycation end products by ACE …


JM Forbes, ME Cooper, V Thallas, WC Burns, MC … - Diabetes, 2002 - Am Diabetes Assoc
Diabetes is characterized by chronic hyperglycemia, which facilitates nonenzymatic browning
in the Maillard reaction between reducing sugars and free reactive amino groups of proteins
(1). Subsequent biochemical modifications result in the irreversible formation of a ...
Cited by 194 - Related articles - BL Direct - All 5 versions

ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe …

- diabetesjournals.org
JL Wilkinson-Berka, DJ Kelly, SM Koerner, K Jaworski, … - Diabetes, 2002 - Am Diabetes Assoc
The severe diabetic nephropathy that develops in the hypertensive transgenic (mRen-2)27 rat
with streptozotocin (STZ) diabetes has previously been considered angiotensin
II-dependent. Because metabolic pathways are also activated in the diabetic kidney, the ...
Cited by 66 - Related articles - BL Direct - All 6 versions

Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end …

- asnjournals.org
M Nangaku, T Miyata, T Sada, M Mizuno, R … - Journal of the American …, 2003 - Am Soc Nephrol
In the present study, we use a strain of a spontaneously hypertensive/NIH-corpulent rat
[SHR/NDmc-cp (fat/fat)] as a model of type 2 DN (6) to unravel the mechanisms of the ARB-induced
renoprotection against DN. We demonstrate a dose-dependent, renoprotective effect of ...
Cited by 94 - Related articles - BL Direct - All 6 versions

[PDF] Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin- …


TP Degenhardt, NL Alderson, DD Arrington, RJ … - Kidney international, 2002 - chem.sc.edu
Department of Chemistry and Biochemistry, Animal Resource Facility, and School of
Medicine, University of South Carolina, Columbia, South Carolina, and Department of Laboratory
Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
Cited by 193 - Related articles - BL Direct - All 6 versions

Renoprotective effects of a novel inhibitor of advanced glycation


JM Forbes, T Soulis, V Thallas, S Panagiotopoulos, DM … - Diabetologia, 2001 - Springer
It has been hypothesized that the biochemical pro- cess of advanced glycation plays an important
part in the pathogenesis of diabetic vascular complications [1] and particularly in diabetic nephropathy
[2]. This hypothesis was based primarily on the renoprotective effects observed with ...
Cited by 109 - Related articles - BL Direct - All 3 versions

The breakdown of pre-existing advanced glycation end products is associated with …

- fasebj.org [PDF] 
JM Forbes, V Thallas, MC Thomas, HW Founds, WC … - The FASEB Journal, 2003 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.02-1102fje. Published online
July 18, 2003. The breakdown of pre-existing advanced glycation end products is
associated with reduced renal fibrosis in experimental diabetes ...
Cited by 127 - Related articles - BL Direct - All 5 versions

[CITATION] van Ypersele de Strihou C, Ueda Y, et al. Angiotensin II receptor antagonists and …


T Miyata - J Am Soc Nephrol, 2002
Cited by 41 - Related articles

Superior renoprotective effects of combination therapy with ACE and AGE …


BJ Davis, JM Forbes, MC Thomas, G Jerums, WC … - Diabetologia, 2004 - Springer
Aims/hypothesis. Diabetic renal disease has been pos- tulated to progress as a result of an interaction
be- tween metabolic and haemodynamic pathways. Our aim was to assess the functional,
structural, molecular and cellular aspects of renal disease in an experimen- tal model of ...
Cited by 53 - Related articles - BL Direct - All 6 versions

LR-90 a new advanced glycation endproduct inhibitor prevents progression of …


JL Figarola, S Scott, S Loera, C Tessler, P Chu, L … - Diabetologia, 2003 - Springer
Aims/hypothesis. Advanced glycation and lipoxidation endproducts have been implicated in
the pathogenesis of diabetic complications, including diabetic nephrop- athy. LR-90, a new advanced
glycation endproduct in- hibitor, was investigated for its effects on the develop- ment of ...
Cited by 54 - Related articles - BL Direct - All 3 versions

[CITATION] van Ypersele de Strihou C, Ueda Y, Ichimori K, Inagi R, Onogi H, Ishikawa N, …


T Miyata - J Am Soc Nephrol, 2002
Cited by 45 - Related articles


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