- ►diabetesjournals.org JL Wilkinson-Berka, DJ Kelly, SM Koerner, K … - Diabetes, 2002 - Am Diabetes Assoc The severe diabetic nephropathy that develops in the hypertensive transgenic
(mRen-2)27 rat with streptozotocin (STZ) diabetes has previously been considered
angiotensin II-dependent. Because metabolic pathways are also activated in ... Cited by 66 - Related articles - BL Direct - All 6 versions
JM Forbes, T Soulis, V Thallas, S … - Diabetologia, 2001 - Springer It has been hypothesized that the biochemical pro- cess of advanced glycation
plays an important part in the pathogenesis of diabetic vascular complications
[1] and particularly in diabetic nephropathy [2]. This hypothesis was based ... Cited by 109 - Related articles - BL Direct - All 3 versions
JL Figarola, S Scott, S Loera, C Tessler, P … - Diabetologia, 2003 - Springer Aims/hypothesis. Advanced glycation and lipoxidation endproducts have been
implicated in the pathogenesis of diabetic complications, including diabetic
nephrop- athy. LR-90, a new advanced glycation endproduct in- hibitor, was ... Cited by 54 - Related articles - BL Direct - All 3 versions
TP Degenhardt, NL Alderson, DD Arrington, … - Kidney international, 2002 - chem.sc.edu Department of Chemistry and Biochemistry, Animal Resource Facility, and School
of Medicine, University of South Carolina, Columbia, South Carolina, and
Department of Laboratory Medicine, University of Minnesota School of ... Cited by 193 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org T MIYATA, Y UEDA, K ASAHI, Y IZUHARA, R … - Journal of the American Society of Nephrology, 2000 - Am Soc Nephrol Abstract. The accumulation in uremic plasma of reactive carbonyl compounds (RCO)
derived from both carbohydrates and lipids ("carbonyl stress") contributes to
uremic toxicity by accelerating the advanced glycation and lipoxidation of ... Cited by 48 - Related articles - BL Direct - All 4 versions
BJ Davis, JM Forbes, MC Thomas, G Jerums, … - Diabetologia, 2004 - Springer Aims/hypothesis. Diabetic renal disease has been pos- tulated to progress as a
result of an interaction be- tween metabolic and haemodynamic pathways. Our aim
was to assess the functional, structural, molecular and cellular aspects of ... Cited by 53 - Related articles - BL Direct - All 6 versions
JM Forbes, ME Cooper, V Thallas, WC Burns, … - Diabetes, 2002 - Am Diabetes Assoc Diabetes is characterized by chronic hyperglycemia, which facilitates
nonenzymatic browning in the Maillard reaction between reducing sugars and free
reactive amino groups of proteins (1). Subsequent biochemical modifications ... Cited by 194 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org M Lassila, KK Seah, TJ Allen, V Thallas, … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol ABSTRACT. Hyperlipidemia not only may be relevant to cardiovascular disease in
diabetes but may also play a role in the development and progression of diabetic
nephropathy. Furthermore, there is increasing evidence that advanced ... Cited by 50 - Related articles - BL Direct - All 7 versions
V Thallas-Bonke, C Lindschau, B Rizkalla, LA … - Diabetes, 2004 - Am Diabetes Assoc This study investigated the role of advanced glycation end products (AGEs) in
mediating protein kinase C (PKC) isoform expression in diabetic nephropathy. In
vitro, vascular smooth muscle cells incubated in a high-glucose (25-mmol/l) ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] JM Forbes, V Thallas, MC Thomas, HW … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-1102fje. Published online
July 18, 2003. The breakdown of pre-existing advanced glycation end ... Cited by 127 - Related articles - BL Direct - All 5 versions
