S Nervi, S Nicodeme, C Gartioux, C Atlan, M … - Diabetes, 2002 - Am Diabetes Assoc We previously described a reduced expression of the protein tyrosine kinase Lck
in T-cells from type 1 diabetic patients, the origin of which is still unknown.
The human lck gene, located on chromosome 1p35-34.3, was evaluated as a ... Cited by 6 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JS Hulme, BJ Barratt, RCJ Twells, JD Cooper, … - Diabetes, 2004 - Am Diabetes Assoc Prior data associating the expression of lymphocyte-specific protein tyrosine
kinase (LCK) with type 1 diabetes, its critical function in lymphocytes, and the
linkage of the region to diabetes in the nonobese diabetic (NOD) mouse ... Cited by 5 - Related articles - BL Direct - All 5 versions
- ►xtranet-isa.com [PDF] S Nervi, R Guinamard, B Delaval, P Lécine, B … - Gene, 2005 - Elsevier A rare mRNA variant of the human lymphocyte-specific protein tyrosine kinase LCK
gene that retains intron B and excludes exon 7 (B + 7 − ) due to alternative
splicing of the canonical LCK transcripts was identified and characterized. ... Related articles - All 4 versions
J Johannesen - Danish Medical Bulletin, 2006 - danmedbul.dk Type 1 diabetes mellitus (T1DM) is an immune mediated disease characterised by
selective destruction of the pancreatic beta-cells in the islets of Langerhans
leading to lack of insulin production capacity, insulin depletion, ... Related articles - Cached - BL Direct - All 5 versions
P Gao, Y Jiao, Q Xiong, CY Wang, I Gerling, … - Current Genomics, 2008 - pubmedcentral.nih.gov A systematic study has been conducted of all available reports in PubMed and
OMIM (Online Mendelian Inheritance in Man) to examine the genetic and molecular
basis of quantitative genetic loci (QTL) of diabetes with the main focus on ... Related articles - All 4 versions
- ►jimmunol.org S Nervi, C Atlan-Gepner, B Kahn-Perles, P … - The Journal of Immunology, 2000 - Am Assoc Immnol Peripheral T lymphocyte activation in response to TCR/CD3 stimulation is reduced
in type 1 diabetic patients. To explore the basis of this deficiency, a
comprehensive analysis of the signal transduction pathway downstream of the ... Cited by 22 - Related articles - BL Direct - All 2 versions
VA Morrison, S Onengut-Gumuscu, P … - Molecular genetics and metabolism, 2004 - Elsevier Type 1 diabetes (T1D) arises from autoimmune destruction of the
insulin-secreting β cells of the pancreas resulting in a complete dependence on
exogenously administered insulin. Both family and twin studies suggest that ... Cited by 8 - Related articles - All 3 versions
- ►diabetesjournals.org [PDF] S Klinger, C Poussin, MB Debril, W Dolci, PA … - Diabetes, 2007 - Am Diabetes Assoc 1 Institute of Physiology, 2 Center for Integrative Genomics, University of
Lausanne, 1015 Lausanne, Switzerland, 3 Department of Genetic Medicine and
Development, University Medical Center, University Hospital, 1211 Geneva 4, ... Cited by 1 - Related articles - All 2 versions
JS Park, SJ Lee, J Myeong, SE Namkoong, … - Proceedings of the American Association for Cancer …, 2003 - kmbase.medric.or.kr Results: With regard to environmental factors, the cervical cancer increased in
the women with a lower level of education, a younger age at first sexual
intercourse and with the increased number of children borne. The women who ... Cited by 1 - Related articles - Cached
SM Ben, N Ghanem, T Kneissi, M Abbal, JM … - Annales de biologie clinique, 1991 - ncbi.nlm.nih.gov 48 Tunisian people suffering from the IDDM auto-immune disease were compared to
35 control healthy persons for the polymorphisms of the complement BF, C2 and C4
proteins and genes, of the IgG (Gm allotypes) as well as of the TNF alpha ... Cited by 1 - Related articles
