H Onuma, H Osawa, K Yamada, T Ogura, F … - Diabetes, 2002 - Am Diabetes Assoc Phosphodiesterase (PDE)-3B, a major PDE isoform in adipocytes, plays a pivotal
role in the antilipolytic action of insulin. Insulin-induced phosphorylation and
activation of PDE3B is phosphatidylinositol 3-kinase (PI3-K) and Akt ... Cited by 25 - Related articles - BL Direct - All 4 versions
MP Rubio, DG Campbell, NA Morrice, C … - Biochemical Journal, 2005 - pubmedcentral.nih.gov PDE3A (phosphodiesterase 3A) was identified as a phosphoprotein that
co-immunoprecipitates with endogenous 14-3-3 proteins from HeLa cell extracts,
and binds directly to 14-3-3 proteins in a phosphorylation-dependent ... Cited by 17 - Related articles - BL Direct - All 7 versions
R Nilsson, F Ahmad, K Swärd, U Andersson, … - Cellular signalling, 2006 - Elsevier Caveolae, plasma membrane invaginations particularly abundant in adipocytes,
have been suggested to be important in organizing insulin signalling.
Insulin-induced activation of the membrane bound cAMP degrading enzyme, ... Cited by 16 - Related articles - All 6 versions
H Onuma, H Osawa, T Ogura, F Tanabe, W … - Biochemical and Biophysical Research …, 2005 - Elsevier Phosphodiesterase 3B (PDE3B), a major PDE isoform in adipocytes, plays a pivotal
role in the anti-lipolytic action of insulin. Insulin phosphorylates and
activates PDE3B in a phosphatidylinositol 3-kinase-dependent manner. We ... Cited by 4 - Related articles - All 4 versions
- ►jbc.org Y Shakur, K Takeda, Y Kenan, ZX Yu, G Rena … - Journal of Biological Chemistry, 2000 - ASBMB Subcellular localization of cyclic nucleotide phosphodiesterases (PDEs) may be
important in compartmentalization of cAMP/cGMP signaling responses. In 3T3-L1
adipocytes, mouse (M) PDE3B was associated with the endoplasmic reticulum ... Cited by 61 - Related articles - BL Direct - All 3 versions
- ►jbc.org CM Rondinone, E Carvalho, T Rahn, VC … - Journal of Biological Chemistry, 2000 - ASBMB Phosphatidylinositol 3-kinase mediates several actions of insulin including its
antilipolytic effect. This effect is elicited by the insulin-stimulated serine
phosphorylation and activation of cGMP-inhibited phosphodiesterase (PDE3B). ... Cited by 39 - Related articles - BL Direct - All 3 versions
AG Kieback, H Iven, K Stolzenburg, E … - International journal of cardiology, 2003 - Elsevier The introduction of PDE III-inhibitors has been a major innovation for the
intravenous drug treatment of patients suffering from heart failure. In this
study, the pharmacokinetics and hemodynamic effects of the PDE ... Cited by 3 - Related articles - All 6 versions
T Rahn, L Rönnstrand, MJ Leroy, C Wernstedt … - Journal of Biological Chemistry, 1996 - ASBMB Stimulation of rat adipocytes with insulin and isoproterenol results in serine
phosphorylation and activation of the adipocyte cGMP-inhibited phosphodiesterase
(cGI PDE), events believed to be important in the antilipolytic action of ... Cited by 41 - Related articles - BL Direct - All 5 versions
C Wu, AJ Muslin - Mechanisms of Development, 2002 - Elsevier 14-3-3 proteins are intracellular dimeric phosphoserine/threonine-binding
molecules that participate in signal transduction and checkpoint control
pathways. 14-3-3 proteins are required for normal eye development, brain ... Cited by 15 - Related articles - All 3 versions
- ►jbc.org J Wechsler, YH Choi, J Krall, F Ahmad, VC … - Journal of Biological Chemistry, 2002 - ASBMB PDE3A cyclic nucleotide phosphodiesterases regulate cAMP- and cGMP-mediated
intracellular signaling in cardiac myocytes. We used antibodies to different
regions of PDE3A to demonstrate the presence of three PDE3A isoforms in ... Cited by 49 - Related articles - BL Direct - All 4 versions
