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Scholar Results 1 - 10 of about 101 related to Sainsbury: Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. (0.10 sec) 

Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice

- diabetesjournals.org
A Sainsbury, C Schwarzer, M Couzens, H … - Diabetes, 2002 - Am Diabetes Assoc
Hypothalamic neuropeptide Y (NPY) is implicated in the regulation of a variety
of physiological functions, notably energy homeostasis and reproduction.
Chronically elevated NPY levels in the hypothalamus, as in genetically ...
Cited by 45 - Related articles - BL Direct - All 4 versions

Attenuation of hypercholesterolemia and hyperglycemia in ob/ob mice by NPY Y2 receptor …


P Naveilhan, L Svensson, S Nyström, AJ … - Peptides, 2002 - ncbi.nlm.nih.gov
Neuropeptide Y (NPY) is a 36 amino acid peptide well known for its role in
regulating food intake and energy homeostasis. It has previously been shown that
the NPY Y2 receptor is required for a full biological response to leptin in ...
Cited by 24 - Related articles - All 3 versions

Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double …

- nih.gov
A Sainsbury, PA Baldock, C Schwarzer, N … - Molecular and Cellular Biology, 2003 - Am Soc Microbiol
Neuropeptide Y regulates numerous physiological processes via at least five
different Y receptors, but the specific roles of each receptor are still
unclear. We previously demonstrated that Y2 receptor knockout results in a ...
Cited by 47 - Related articles - BL Direct - All 4 versions

Y4 receptor knockout rescues fertility in ob/ob mice

- cshlp.org
A Sainsbury, C Schwarzer, M Couzens, A … - Genes & development, 2002 - genesdev.cshlp.org
Hypothalamic neuropeptide Y (NPY) has been implicated in the regulation of
energy balance and reproduction, and chronically elevated NPY levels in the
hypothalamus are associated with obesity and reduced reproductive function. ...
Cited by 78 - Related articles - BL Direct - All 7 versions

Y2Y4 receptor double knockout protects against obesity due to a high-fat diet or Y1 receptor …

- shouxi.net
A Sainsbury, HT Bergen, D Boey, D Bamming, … - Diabetes, 2006 - Am Diabetes Assoc
Neuropeptide Y receptors are critical regulators of energy homeostasis, but the
functional interactions and relative contributions of Y receptors and the
environment in this process are unknown. We measured the effects of an ad ...
Cited by 15 - Related articles - BL Direct - All 6 versions

Important role of hypothalamic Y2 receptors in body weight regulation revealed in …

- pnas.org
A Sainsbury, C Schwarzer, M Couzens, S … - Proceedings of the National Academy of Sciences, 2002 - National Acad Sciences
Neuropeptide Y is implicated in energy homeostasis, and contributes to obesity
when hypothalamic levels remain chronically elevated. To investigate the
specific role of hypothalamic Y2 receptors in this process, we used a ...
Cited by 121 - Related articles - BL Direct - All 10 versions

Compensatory changes in [125I]-PYY binding in Y receptor knockout mice suggest the …


S Lin, D Boey, M Couzens, N Lee, A … - Neuropeptides, 2005 - Elsevier
Gene knockout approaches have helped to better understand the functions of the
different Y receptors. However, some results obtained from these knockout mice
are unexpected and differ from the results of pharmacological intervention ...
Cited by 21 - Related articles - All 7 versions

Common neuropeptide Y2 receptor gene variant is protective against obesity among …


C Lavebratt, A Alpman, B Persson, P Arner, J … - International Journal of Obesity, 2005 - nature.com
Gut hormones and their receptors are considered important in the control of
feeding behavior. The gut hormone peptide-YY (PYY) has anorexic effects via the
inhibitory neuropeptide Y2 receptor (Y2R) highly expressed in orexigenic ...
Cited by 25 - Related articles - BL Direct - All 5 versions

The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis …

- fasebj.org [PDF] 
FP Pralong, C Gonzales, MJ Voirol, RD … - The FASEB Journal, 2002 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.01-0754fje. Published online
March 12, 2002. The neuropeptide Y Y1 receptor regulates leptin-mediated ...
Cited by 53 - Related articles - BL Direct - All 4 versions

Selective activation of central NPY Y1 vs. Y5 receptor elicits hyperinsulinemia via distinct …

- physiology.org
J Gao, L Ghibaudi, JJ Hwa - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
Central administration of neuropeptide Y (NPY) stimulates hyperphagia and
hyperinsulinemia. Recent evidence has suggested that the Y1 and Y5 receptor
subtypes may both mediate NPY-stimulated feeding. The present study ...
Cited by 9 - Related articles - BL Direct - All 4 versions


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