Y Pang, DL Hunton, P Bounelis, RB Marchase - Diabetes, 2002 - Am Diabetes Assoc Hyperglycemia alters cardiac function and often leads to diabetic cardiomyopathy
as cardiomyocyte apoptosis causes a hypertrophied heart to deteriorate to
dilation and failure. Paradoxically, many short-term animal models of ... Cited by 46 - Related articles - BL Direct - All 5 versions
- ►physiology.org T Nagy, V Champattanachai, RB Marchase, … - American Journal of Physiology- Cell Physiology, 2006 - Am Physiological Soc We previously reported that glucosamine and hyperglycemia attenuate the response
of cardiomyocytes to inositol 1,4,5-trisphosphate-generating agonists such as
ANG II. This appears to be related to an increase in flux through the ... Cited by 31 - Related articles - BL Direct - All 3 versions
Y Pang, P Bounelis, JC Chatham, RB … - Diabetes, 2004 - Am Diabetes Assoc Hyperglycemia diminishes positive inotropic responses to agonists that activate
phospholipase C (PLC) and generate inositol trisphosphate (1,4,5). The
mechanisms underlying both the inotropic responses and hyperglycemia's ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►critcaremed.com S Yang, L Zou, P Bounelis, I Chaudry, JC … - Shock, 2006 - journals.lww.com Received 17 Oct 2005; first review completed 10 Nov 2005; accepted in final form
3 Jan 2006 ABSTRACT—Stress-induced hyperglycemia is necessary for maximal
rates of survival after severe hemorrhage; however, the responsible ... Cited by 20 - Related articles - BL Direct - All 8 versions
J Liu, Y Pang, T Chang, P Bounelis, JC … - Journal of molecular and cellular cardiology, 2006 - Elsevier Increased hexosamine biosynthesis pathway (HBP) flux and elevated levels of
protein O-linked-N-acetylglucosamine (O-GlcNAc) decrease calcium influx into
isolated cardiomyocytes. Increased O-GlcNAc levels also increase tolerance ... Cited by 37 - Related articles - All 7 versions
S Vemuri, RB Marchase - Journal of Biological Chemistry, 1999 - ASBMB The capacitative Ca 2+ entry pathway in J774 macrophages is rapidly inhibited by
the amino sugar glucosamine. This pathway is also inhibited by treatments such
as 2-deoxy-d-glucose (2dGlc) or glucose deprivation that inhibit glycolysis ... Cited by 15 - Related articles - BL Direct - All 5 versions
KC Sohn, KY Lee, JE Park, SI Do - Biochemical and biophysical research communications, 2004 - Elsevier Protein O-GlcNAcylation is proceeded by O-linked GlcNAc transferase (OGT) in
nucleocytoplasm and is involved in many biological processes although its
physiological role is not clearly defined. To identify the functional ... Cited by 27 - Related articles - All 5 versions
- ►physiology.org V Champattanachai, RB Marchase, JC … - American Journal of Physiology- Cell Physiology, 2007 - Am Physiological Soc Increased levels of protein O-linked N-acetylglucosamine (O-GlcNAc) have been
shown to increase cell survival following stress. Therefore, the goal of this
study was to determine whether in isolated neonatal rat ventricular ... Cited by 29 - Related articles - BL Direct - All 6 versions
- ►physiology.org N Fulop, Z Zhang, RB Marchase, JC Chatham - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc We have shown that, in the perfused heart, glucosamine improved functional
recovery following ischemia and that this appeared to be mediated via an
increase in O-linked N-acetylglucosamine (O-GlcNAc) levels on ... Cited by 15 - Related articles - BL Direct - All 3 versions
- ►physiology.org J Liu, RB Marchase, JC Chatham - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc We have previously shown that preischemic treatment with glucosamine improved
cardiac functional recovery following ischemia-reperfusion, and this was
mediated, at least in part, via enhanced flux through the hexosamine ... Cited by 15 - Related articles - BL Direct - All 3 versions
