- ►diabetesjournals.org SK Rasmussen, SA Urhammer, L Berglund, JN Jensen, … - Diabetes, 2002 - Am Diabetes Assoc Variations in the calpain-10 gene (CAPN10) have been identified among
Mexican-Americans, and an at-risk haplotype combination (112/121) defined by three
polymorphisms, UCSNP-43, -19, and -63, confers increased risk of type 2 diabetes. Here ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►endojournals.org Y Horikawa, N Oda, L Yu, S Imamura, K … - Journal of Clinical …, 2003 - Endocrine Soc The 112/121 haplotype combination defined by the UCSNP-43, -19, and -63 alleles in the
calpain-10 gene is associated with type 2 diabetes in Mexican Americans. To determine whether
this genetic variation constitutes risk of type 2 diabetes in Japanese, we investigated its ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org TE Fingerlin, MR Erdos, RM Watanabe, KR Wiles, HM … - Diabetes, 2002 - Am Diabetes Assoc Variations in the calpain-10 gene have recently been reported to be associated with type 2 diabetes
in a Mexican-American population. We typed three single nucleotide polymorphisms (SNPs)
in the calpain-10 gene (SNPs 43, 56, and 63) to test for association between variation at ... Cited by 54 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org M Orho-Melander, M Klannemark, MK Svensson, M … - Diabetes, 2002 - Am Diabetes Assoc The calpain-10 gene (CAPN10) has been associated with type 2 diabetes, but information on
molecular and physiological mechanisms explaining this association is limited. Here we addressed
this question by studying the role of CAPN10 for phenotypes associated with type 2 ... Cited by 77 - Related articles - BL Direct - All 4 versions
M Daimon, T Oizumi, T Saitoh, W Kameda, H … - Diabetes research and …, 2002 - Elsevier A G-to-A (UCSNP-43) polymorphism of the calpain-10 gene was significantly associated with
type 2 diabetes (DM) in Mexican–American, and was postulated, together with a T-to-C
(UCSNP-44) polymorphism, as a risk factor for DM. We examined the association of these ... Cited by 57 - Related articles - All 7 versions
MJ Garant, WH Kao, F Brancati, J Coresh, TM Rami, CL … - Diabetes, 2002 - ncbi.nlm.nih.gov Recently, an A-to-G variant in intron 3 (SNP43) of the calcium-activated neutral protease 10 gene
(CAPN10) was identified as a possible type 2 diabetes susceptibility gene through positional
cloning in Mexican-Americans. We conducted cross-sectional and prospective studies to ... Cited by 54 - Related articles - BL Direct - All 2 versions
- ►nih.gov JC Evans, TM Frayling, PG Cassell, PJ Saker, GA … - The American Journal of …, 2001 - Elsevier Variation in CAPN10, the gene encoding the ubiquitously expressed cysteine protease
calpain-10, has been associated with type 2 diabetes in Mexican Americans and in two
northern-European populations, from Finland and Germany. We have studied CAPN10 in ... Cited by 137 - Related articles - BL Direct - All 11 versions
- ►nih.gov HJ Tsai, G Sun, DE Weeks, R Kaushal, M … - The American Journal of …, 2001 - Elsevier Although genomewide scans have identified several potential chromosomal susceptibility regions
in several human populations, finding a causative gene for type 2 diabetes has remained
elusive. Others have reported a novel gene, calpain-10 (CAPN10), located in a previously ... Cited by 85 - Related articles - BL Direct - All 7 versions
- ►eje-online.org [PDF] MT Malecki, DK Moczulski, T Klupa, K Wanic, K … - European Journal of …, 2002 - EFES Objective: The polymorphisms of two genes have recently been associated with complex forms
of type 2 diabetes mellitus (T2DM): calpain 10 and peroxisome proliferator-activated
receptor-g (PPARg). Cal- pain 10 is a member of a large family of intracellular proteases. ... Cited by 63 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org [PDF] RA Hegele, SB Harris, B Zinman, AJG Hanley, H … - Diabetes Care, 2001 - Am Diabetes Assoc Animal studies have demonstrated lower levels of 1,25(OH)2D3 in a type 2 diabetes model compared
with controls (1). Alterations in circulat- ing vitamin D3 metabolites, such as de- creased 1-hydroxylase
activity and enhanced renal 25-hydroxylase activity, have been found in both ... Cited by 48 - Related articles - BL Direct - All 5 versions
