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Scholar Results 1 - 10 of about 101 related to Adams: Calcineurin inhibitor–free CD28 blockade-based protocol protects allogeneic islets.... (0.14 sec) 

Calcineurin inhibitor–free CD28 blockade-based protocol protects allogeneic islets in …

- diabetesjournals.org
AB Adams, N Shirasugi, MM Durham, E … - Diabetes, 2002 - Am Diabetes Assoc
Recent success using a steroid-free immunosuppressive regimen has renewed
enthusiasm for the use of islet transplantation to treat diabetes. Toxicities
associated with the continued use of a calcineurin inhibitor may limit the ...
Cited by 98 - Related articles - BL Direct - All 4 versions

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to …

- jimmunol.org
AB Adams, N Shirasugi, TR Jones, MM Durham … - The Journal of Immunology, 2005 - Am Assoc Immnol
In recent years, reagents have been developed that specifically target signals
critical for effective T cell activation and function. Manipulation of the
CD28/CD80/86 and CD40/CD154 pathways has exhibited extraordinary efficacy, ...
Cited by 79 - Related articles - All 8 versions

Rapid Publication


CIFCD Blockade-Based - DIABETES, 2002 - Am Diabetes Assoc
Recent success using a steroid-free immunosuppressive regimen has renewed
enthusiasm for the use of islet transplantation to treat diabetes. Toxicities
associated with the continued use of a calcineurin inhibitor may limit the ...
Related articles - All 3 versions

Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function …


JM Thomas, JL Contreras, CA Smyth, A … - Diabetes, 2001 - Am Diabetes Assoc
The recent focus on islet transplantation as primary therapy for type 1 diabetes
has heightened interest in the reversal of type 1 diabetes in preclinical models
using minimal immunosuppression. Here, we demonstrated in a preclinical ...
Cited by 65 - Related articles - BL Direct - All 10 versions

Central administration of oleic acid inhibits glucose production and food intake


S Obici, Z Feng, K Morgan, D Stein, G … - Diabetes, 2002 - Am Diabetes Assoc
The hypothalamus and other regions within the central nervous system (CNS) link
the sensing of nutrients to the control of metabolism and feeding behavior.
Here, we report that intracerebroventricular (ICV) administration of the ...
Cited by 218 - Related articles - BL Direct - All 5 versions

Rapid Publication


S Obici, Z Feng, K Morgan, D Stein, G … - DIABETES, 2002 - Am Diabetes Assoc
The hypothalamus and other regions within the central nervous system (CNS) link
the sensing of nutrients to the control of metabolism and feeding behavior.
Here, we report that intracerebroventricular (ICV) adminis- tration of the ...
Related articles - All 2 versions

Induction therapy with monoclonal antibodies specific for cd80 and cd86 delays the onset of …


AD Kirk, DK Tadaki, A Celniker, D Scott … - Transplantation, 2001 - journals.lww.com
Kirk, Allan D.; Tadaki, Douglas K.; Celniker, Abbie; Scott Batty, D.; Berning,
Justin D.; Colonna, John O.; Cruzata, Francis; Elster, Eric A.; Gray, Gary S.;
Kampen, Robert L.; Patterson, Noelle B.; Szklut, Pam; Swanson, John; Xu, ...
Cited by 85 - Related articles - BL Direct - All 4 versions

Anti-CD40 therapy extends renal allograft survival in rhesus macaques1


TC Pearson, J Trambley, K Odom, DC Anderson … - Transplantation, 2002 - journals.lww.com
Background. Organ transplant recipients currently require lifetime
immunosuppressive therapy, with its accompanying side effects. Biological agents
that block T-cell costimulatory pathways are important components of ...
Cited by 69 - Related articles - BL Direct - All 3 versions

Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic …


MG Levisetti, PA Padrid, GL Szot, N Mittal, … - The Journal of Immunology, 1997 - Am Assoc Immnol
A dvances in organ preservation and pancreatic islet iso- lation techniques have
made the use of islet grafts an important new approach to the treatment of
insulin-de- pendent diabetes mellitus. However, T lymphocyte-mediated graft ...
Cited by 150 - Related articles - BL Direct - All 3 versions

Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, …


M Wijkstrom, NS Kenyon, N Kirchhof, NM … - TRANSPLANTATION-BALTIMORE-, 2004 - 万方数据资源系统
OBJECTIVE: In a preclinical, nonhuman primate islet allotransplant model, the
authors evaluated a novel immunosuppressive combination of basiliximab for
induction and of RAD and FTY720 for maintenance. METHODS: Five ...
Cited by 42 - Related articles - BL Direct - All 3 versions


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