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Scholar Results 1 - 10 of about 101 related to Smih: Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose. (0.09 sec) 

Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose


F Smih, P Rouet, S Lucas, A Mairal, C Sengenes, M … - Diabetes, 2002 - Am Diabetes Assoc
Hormone-sensitive lipase (HSL) catalyzes the rate-limiting step in the mobilization of fatty acids
from adipose tissue, thus determining the supply of energy substrates in the body. HSL mRNA
was positively regulated by glucose in human adipocytes. Pools of stably transfected 3T3- ...
Cited by 65 - Related articles - BL Direct - All 6 versions

Two initiator-like elements are required for the combined activation of the human …


D Pastier, JM Lacorte, J Chambaz, P Cardot, A … - Journal of Biological …, 2002 - ASBMB
Human apoC-III (−890/+24) promoter activity is strongly activated by hepatic nuclear factor
(HNF)-4 through its binding to the proximal (−87/−72) element B. This site overlaps the binding
site for an activity that we identified as the ubiquitously expressed upstream stimulatory ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Identification of upstream stimulatory factor as transcriptional activator of the liver …

- nih.gov [PDF] 
PB Iynedjian - Biochemical Journal, 1998 - pubmedcentral.nih.gov
A functionally important cis-acting element termed P2 was identified in the liver promoter of the
glucokinase gene. Element P2 was delineated by footprinting in itro with nuclear proteins from
rat liver and spleen. Its core sequence in the rat gene is a canonical CACGTG E-box. In ...
Cited by 49 - Related articles - BL Direct - All 7 versions

Regulation of hormone-sensitive lipase expression by glucose in 3T3-F442A …


T Raclot, M Dauzats, D Langin - Biochemical and Biophysical Research …, 1998 - Elsevier
Hormone-sensitive lipase (HSL) catalyzes the rate-limiting step in adipocyte lipolysis. We have
studied the effect of glucose and long chain fatty acids on the HSL mRNA content of 3T3-F442A
adipocytes. Exposure of the cells for 32 h to a medium without glucose led to a decrease ...
Cited by 22 - Related articles - BL Direct - All 7 versions

[PDF] L ong-Term Regulation of Lipolysis and Hormone-Sensitive Lipase by Insulin and …


LM Botion, A Green - Diabetes, 1999 - Am Diabetes Assoc
Adipocyte glucose transport can be impaired by pro- longed hyperglycemic conditions.
However, at the whole body level, lipolysis is quantitatively a more important function of adipocytes
than glucose uptake. We have therefore investigated the effect of prolonged high glucose ...
Cited by 48 - Related articles - BL Direct - All 5 versions

Cooperative binding of upstream stimulatory factor and hepatic nuclear factor 4 …

- jbc.org
A Ribeiro, D Pastier, D Kardassis, J Chambaz, P … - Journal of Biological …, 1999 - ASBMB
The activity of the human apoA-II promoter is controlled by a synergistic interaction of the distal
enhancer and the proximal promoter. An important role in apoA-II promoter activity is exerted
by a transcription factor, designated CIIIB1, which binds to the proximal element AB and ...
Cited by 70 - Related articles - BL Direct - All 4 versions

Essential role in vivo of upstream stimulatory factors for a normal dietary response …

- jbc.org
M Casado, VS Vallet, A Kahn, S Vaulont - Journal of Biological Chemistry, 1999 - ASBMB
In the liver, transcription of several genes encoding lipogenic and glycolytic enzymes, in particular
the gene for fatty acid synthase (FAS), is known to be stimulated by dietary carbohydrates. The
molecular dissection of the FAS promoter pointed out the critical role of an E box motif, ...
Cited by 103 - Related articles - BL Direct - All 6 versions

Promoter I of the ovine acetyl-CoA carboxylase-alpha gene: an E-box motif at-114 …

- nih.gov [PDF] 
MT Travers, AJ Vallance, HT Gourlay, CA Gill … - Biochemical …, 2001 - pubmedcentral.nih.gov
Maureen T. TRAVERS*, Amanda J. VALLANCE*, Helen T. GOURLAY*, Clare A. GILL†1, Izabella
KLEIN*2, Cynthia BK BOTTEMA† and Michael C. BARBER*3 *Hannah Research Institute, Hannah
Research Park, Ayr KA6 5HL, UK, and †Department of Animal Science, Roseworthy ...
Cited by 29 - Related articles - BL Direct - All 7 versions

Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions …

- sinoas.com [PDF] 
GJ Botma, AJM Verhoeven, H Jansen - Atherosclerosis, 2001 - Elsevier
The common −216G→A and −480C→T substitutions in the promoter region of the human hepatic
lipase (LIPC) gene show high allelic association, and are correlated with decreased hepatic
lipase activity and increased high-density lipoprotein cholesterol levels. To test the ...
Cited by 58 - Related articles - All 10 versions

The E-box motif in the proximal ABCA1 promoter mediates transcriptional …

- jlr.org
XP Yang, LA Freeman, CL Knapper, MJA Amar, A … - The Journal of Lipid …, 2002 - ASBMB
To identify regulatory elements in the proximal human ATP-binding cassette transporter A1
(hABCA1) gene promoter we transfected RAW cells with plasmids containing mutations in the
E-box, AP1, and liver X receptor (LXR) elements as well as the two Sp1 motifs. Point ...
Cited by 60 - Related articles - BL Direct - All 3 versions


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