P Shah, A Vella, A Basu, R Basu, A Adkins, WF … - Diabetes, 2002 - Am Diabetes Assoc The present study sought to determine whether elevated plasma free fatty acids (FFAs) alter
the ability of insulin and glucose to regulate splanchnic as well as muscle glucose
metabolism. To do so, FFAs were increased in 10 subjects to ∼1 mmol/l by an 8-h ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org M Bajaj, T Pratipanawatr, R Berria, W Pratipanawatr, S … - Diabetes, 2002 - Am Diabetes Assoc Splanchnic glucose uptake (SGU) plays a major role in the disposal of an oral glucose load
(OGL). To investigate the effect of an elevated plasma free fatty acid (FFA) concentration on SGU
in patients with type 2 diabetes, we measured SGU in eight diabetic patients (mean age ... Cited by 14 - Related articles - BL Direct - All 6 versions
- ►physiology.org M Bajaj, R Berria, T Pratipanawatr, S … - American Journal of …, 2002 - Am Physiological Soc To investigate the effect of elevated plasma free fatty acid (FFA) concentrations on splanchnic
glucose uptake (SGU), we measured SGU in nine healthy subjects (age, 44 ± 4 yr; body mass
index, 27.4 ± 1.2 kg/m 2 ; fasting plasma glucose, 5.2 ± 0.1 mmol/l) during an Intralipid- ... Cited by 29 - Related articles - BL Direct - All 5 versions
J Kuyumjian, N Kalant - Horm Metab Res, 1986 - thieme-connect.com Absorption of glucose from the gut was estimated in trained unanesthetized dogs given a glucose
load of 1-25 g ( 14 C)glucose by stomach tube. The rate of absorption of glucose was calculated
from the concentration and specific activity of glucose in the portal vein and in an “ ... Cited by 7 - Related articles - All 3 versions
- ►diabetesjournals.org A Basu, R Basu, P Shah, A Vella, CM Johnson, M … - Diabetes, 2001 - Am Diabetes Assoc We have previously reported that splanchnic glucose uptake, hepatic glycogen synthesis, and
hepatic glucokinase activity are decreased in people with type 2 diabetes during intravenous
glucose infusion. To determine whether these defects are also present during more ... Cited by 63 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] A Basu, R Basu, P Shah, A Vella, CM Johnson, KS Nair … - Diabetes, 2000 - Am Diabetes Assoc Insulin-induced stimulation of muscle glucose uptake (MGU) is impaired in people with type 2
diabetes. To determine whether insulin-induced stimulation of splanchnic glucose uptake
(SGU) is also impaired, we simultaneously measured leg glucose uptake (LGU) and SGU ... Cited by 77 - Related articles - BL Direct - All 5 versions
V Rigalleau, C Binnert, K Minehira, N Stefanoni, P … - Diabetes, 2001 - Am Diabetes Assoc Raising plasma free fatty acid (FFA) levels reduces muscle glucose uptake, but the effect of FFAs
on splanchnic glucose uptake, total glucose output, and glucose cycling may also be critical
to producing lipid-induced glucose intolerance. In eight normal volunteers, we measured ... Cited by 17 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] B Ludvik, JJ Nolan, A Roberts, J Baloga, … - Journal of Clinical …, 1995 - pubmedcentral.nih.gov We have developed a noninvasive method to estimate splanchnic glucose uptake (SGU) in humans
(oral glucose clamp technique [OG-CLAMP]), which combines a hyper- insulinemic clamp with
an oral glucose load (oral glucose tolerance test). We validated this method in 12 ... Cited by 31 - Related articles - BL Direct - All 7 versions
M Roden, H Stingl, V Chandramouli, WC … - DIABETES-NEW …, 2000 - Am Diabetes Assoc Effects of free fatty acids (FFAs) on endogenous glu- cose production (EGP) and gluconeogenesis
(GNG) were examined in healthy subjects (n = 6) during step- wise increased Intralipid/heparin
infusion (plasma FFAs 0.8 ± 0.1, 1.8 ± 0.2, and 2.8 ± 0.3 mmol/l) and dur- ing glycerol ... Cited by 154 - Related articles - BL Direct - All 5 versions
J Radziuk, S Pye - Diabetologia, 2001 - Springer The relative importance of glucose over-production and inadequate peripheral removal in the
postab- sorptive (fasting) hyperglycaemia of Type II (non-in- sulin dependent) diabetes mellitus
has produced di- verse estimates. Some studies show that a strong cor- relation exists ... Cited by 12 - Related articles - BL Direct - All 4 versions