S Thiessen, P Serra, A Amrani, J Verdaguer, … - Diabetes, 2002 - Am Diabetes Assoc For poorly understood reasons, the development of autoimmune diabetes in humans
and mice is dominantly inhibited by major histocompatibility complex (MHC) class
II molecules with diverse antigen-binding sites. We have previously shown ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org D Schmidt, A Amrani, J Verdaguer, S Bou, P … - The Journal of Immunology, 1999 - Am Assoc Immnol Some MHC class II genes provide dominant resistance to certain autoimmune
diseases via mechanisms that remain unclear. We have shown that thymocytes
bearing a highly diabetogenic, IA g7 -restricted ß-cell-reactive TCR ... Cited by 37 - Related articles - BL Direct - All 3 versions
[CITATION] Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of NOD …
- ►jimmunol.org T Takaki, SM Lieberman, TM Holl, B Han, P … - The Journal of Immunology, 2004 - Am Assoc Immnol The NOD mouse is a model for autoimmune type 1 diabetes in humans. CD8 + T cells
are essential for the destruction of the insulin-producing pancreatic cells
characterizing this disease. AI4 is a pathogenic CD8 + T cell clone, ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org A Ueno, S Cho, L Cheng, Z Wang, B Wang, Y … - The Journal of Immunology, 2005 - Am Assoc Immnol Polymorphism of MHC and MHC-linked genes is tightly associated with
susceptibility to type 1 diabetes (T1D) in human and animal models. Despite the
extensive studies, however, the role of MHC and MHC-linked genes expressed ... Cited by 3 - Related articles - BL Direct - All 5 versions
Y Yang, P Santamaria - Diabetologia, 2003 - Springer Type 1 diabetes results from a genetically and immu- nologically complex
autoimmune process that is spe- cifically directed against the pancreatic beta
cells. Non-obese diabetic mice spontaneously develop a form of autoimmune ... Cited by 21 - Related articles - BL Direct - All 4 versions
Y Yang, P Santamaria - Journal of Autoimmunity, 2004 - Elsevier Insulin-dependent diabetes mellitus (Type 1 Diabetes, T1D) in humans and
nonobese diabetic (NOD) mice is the result of a chronic autoimmune process
directed against the pancreatic beta cells [1 and 2]. There is extensive ... Cited by 4 - Related articles - All 3 versions
D Schmidt, J Verdaguer, N Averill, P … - The Journal of Experimental Medicine, 1997 - ukpmc.ac.uk Certain major histocompatibility complex (MHC) class II haplotypes encode
elements providing either susceptibility or dominant resistance to the
development of spontaneous autoimmune diseases via mechanisms that remain ... Related articles
- ►rupress.org D Schmidt, J Verdaguer, N Averill, P … - Journal of Experimental Medicine, 1997 - jem.rupress.org Certain major histocompatibility complex (MHC) class II haplotypes encode
elements providing either susceptibility or dominant resistance to the
development of spontaneous autoimmune diseases via mechanisms that remain ... Cited by 147 - Related articles - BL Direct - All 5 versions
[CITATION] Prevention of insulin-dependent diabetes in NOD mice by transgenes encoding modified IA …
