- ►diabetesjournals.org D Han, X Xu, RL Pastori, C Ricordi, NS Kenyon - Diabetes, 2002 - Am Diabetes Assoc Hyperglycemia and increased insulin requirements are indicators of ongoing islet allograft
rejection, but there are no methods to predict or confirm rejection. Elevation of cytotoxic lymphocyte
(CL) gene expression in peripheral blood (PB) has been correlated with renal allograft ... Cited by 21 - Related articles - BL Direct - All 4 versions
D Han, X Xu, D Baidal, J Leith, C Ricordi, R Alejandro, … - Diabetes, 2004 - Am Diabetes Assoc Studies in nonhuman primates have demonstrated that elevation of the cytotoxic lymphocyte
(CL) genes granzyme B, perforin, and Fas ligand in peripheral blood precedes islet allograft
rejection. The purpose of this study was to determine whether this approach has utility for ... Cited by 33 - Related articles - BL Direct - All 6 versions
D Han, X Xu, RL Pastori, C Ricordi, NS Kenyon - Diabetes, 2002 - Am Diabetes Assoc Hyperglycemia and increased insulin requirements are indicators of ongoing islet allograft
rejection, but there are no methods to predict or confirm rejection. Eleva- tion of cytotoxic lymphocyte
(CL) gene expression in peripheral blood (PB) has been correlated with renal allograft ... Related articles - All 3 versions
- ►diabetesjournals.org B Ritz-Laser, J Oberholzer, C Toso, MC Brulhart, K … - Diabetes, 2002 - Am Diabetes Assoc Islet transplantation is a promising treatment for type 1 diabetes. However, islet grafts are submitted
to multiple injuries, including immunosuppressive drug toxicity, hyperglycemia, hypoxia, unspecific
inflammatory reactions, as well as allo- and autoimmune destruction. Therapeutic ... Cited by 10 - Related articles - BL Direct - All 4 versions
KE Lunsford, D Gao, AM Eiring, Y Wang, WL Frankel, … - Transplantation, 2004 - journals.lww.com Background. Transplant rejection has generally been considered a CD4 T–cell-dependent immune
process. CD4- independent, CD8 T-cell rejection pathways have recently gained attention because
of their relative resistance to immunosuppression. In the current study, the role of the ... Cited by 16 - Related articles - BL Direct - All 4 versions
GL Bumgardner, D Gao, J Li, A Bickerstaff, CG Orosz - Transplantation, 2002 - journals.lww.com 17. Mathew JM, Garcia-Morales R, Fuller L, et al. Donor bone marrow- derived chimeric cells
present in renal transplant recipients infused with donor marrow. I. Potent regulators of recipient
antidonor immune responses. Transplantation 2000; 70: 1675. 18. Mathew JM, Miller J. ... Cited by 10 - Related articles - BL Direct - All 4 versions
Y Wang, D Gao, KE Lunsford, WL Frankel, … - American Journal of …, 2003 - interscience.wiley.com Allogeneic hepatocytes elicit CD4-dependent and (CD4-independent) CD8 + T-cell-initiated
graft rejection. The (CD4-independent) CD8 + T-cell pathway is resistant to immunosuppressive
strategies that readily and indefinitely suppress CD4 + T-cell-dependent rejection ... Cited by 21 - Related articles - BL Direct - All 3 versions
[CITATION] Procurement of the human pancr éas for pancreatic islet isolation
- ►highwire.org S Kommajosyula, S Reddy, K Nitschke, JR … - Journal of Leukocyte …, 2001 - jleuk.highwire.org Leukocytes infiltrate the pancreatic islets of nonobese diabetic mice, causing ß-cell destruction
and autoimmune Type I diabetes. Here, we completely blocked adoptive transfer of diabetes
and reduced spontaneous disease incidence from 71% to 17% by simultaneously ... Cited by 15 - Related articles - BL Direct - All 5 versions