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Scholar Results 1 - 10 of about 101 related to Hamilton-Wessler: Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in.... (0.07 sec) 

Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb


M Hamilton-Wessler, M Ader, MK Dea, D … - Diabetes, 2002 - Am Diabetes Assoc
A defect in transcapillary transport of insulin in skeletal muscle and adipose
tissue has been proposed to play a role in the insulin resistance that leads to
type 2 diabetes, yet the mechanism of insulin transfer across the capillary ...
Cited by 26 - Related articles - BL Direct - All 4 versions

[CITATION] Measurement of insulin detemir and human insulin in adipose and muscle tissue of diabetic …


M Bodenlenz, HC Schaller, A Wutte, LV … - Poster presented at: 38th Annual Meeting of the …
Cited by 5 - Related articles

Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose …


MK Dea, M Hamilton-Wessler, M Ader, D Moore, … - Diabetes, 2002 - Am Diabetes Assoc
NN304 [Lys B29 -tetradecanoyl des(B30) human insulin] is a potentially
therapeutic insulin analog designed to exhibit protracted glucose-lowering
action. In dogs with infusion rates similar to insulin itself, NN304 ...
Cited by 35 - Related articles - BL Direct - All 5 versions

Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor- …

- nih.gov [PDF] 
GM Steil, M Ader, DM Moore, K Rebrin, RN … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov
J. Clin. Invest. © The American Society for Clinical Investigation, Inc.
0021-9738/96/03/1497/07 $2.00 Volume 97, Number 6, March 1996, 1497–1503 ...
Transendothelial Insulin Transport Is Not Saturable In Vivo
Cited by 66 - Related articles - BL Direct - All 8 versions

Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: …


M Hamilton-Wessler, M Ader, M Dea, D … - Diabetologia, 1999 - Springer
Over the last decade, extensive effort has been dedi- cated to the development
of soluble human insulin analogues with a more prolonged and reproducible ...
Mechanism of protracted metabolic effects of fatty acid acylated
Cited by 46 - Related articles - BL Direct - All 3 versions

The vascular endothelial cell mediates insulin transport into skeletal muscle

- physiology.org
H Wang, Z Liu, G Li, EJ Barrett - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
The pathways by which insulin exits the vasculature to muscle interstitium have
not been characterized. In the present study, we infused FITC-labeled insulin to
trace morphologically (using confocal immunohistochemical methods) insulin ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Crystal Structure of a Prolonged-Acting Insulin with Albumin-Binding Properties†


JL Whittingham, S Havelund, I Jonassens - Biochemistry, 1997 - pubs.acs.org
The fatty acid acylated insulin, Lys B29 -tetradecanoyl, des-(B30) human
insulin, has been crystallized and the structure determined by X-ray
crystallography. The fatty acid substituent on residue B29 Lys binds ...
Cited by 45 - Related articles - BL Direct - All 5 versions

[CITATION] Pharmacokinetics of insulin detemir in subjects with renal or hepatic impairment


LV Jacobsen, G Popescu, A Plum - Diabetes, 2002
Cited by 19 - Related articles

Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin- …

- diabetesjournals.org
M Ellmerer, SP Kim, M Hamilton-Wessler, K … - Diabetes, 2004 - Am Diabetes Assoc
Pharmacological doses of insulin increase limb blood flow and enhance tissue
recruitment for small solutes such as glucose. We investigated whether elevating
insulin within the physiological range (68 ± 6 vs. 425 ± 27 pmol/l) can ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Delayed transcapillary transport of insulin to muscle interstitial fluid in obese subjects

- diabetesjournals.org
M Sjöstrand, S Gudbjörnsdottir, A Holmäng, L … - Diabetes, 2002 - Am Diabetes Assoc
Insulin-resistant subjects have a slow onset of insulin action, and the
underlying mechanism has not been determined. To evaluate whether a delayed
transcapillary transport is part of the peripheral insulin resistance, we ...
Cited by 39 - Related articles - BL Direct - All 5 versions


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