S Munro, DJR Cuthbertson, J Cunningham, M Sales, … - Diabetes, 2002 - Am Diabetes Assoc Insulin has been previously shown to regulate the expression of the hepatic glycogen-targeting
subunit, G L , of protein phosphatase 1 (PP1) and is believed to control the activity of the
PP1-G L complex by modulation of the level of phosphorylase a, which allosterically ... Cited by 23 - Related articles - BL Direct - All 5 versions
S Munro, H Ceulemans, M Bollen, J Diplexcito, … - FEBS …, 2005 - interscience.wiley.com Stimulation of glycogen-targeted protein phosphatase 1 (PP1) activity by insulin contributes to
the dephosphorylation and activation of hepatic glycogen synthase (GS) leading to an increase
in glycogen synthesis. The glycogen-targeting subunits of PP1, G L and R5/PTG, are ... Cited by 15 - Related articles - All 5 versions
R Gasa, PB Jensen, HK Berman, MJ Brady, AA … - Journal of Biological …, 2000 - ASBMB Glycogen-targeting subunits of protein phosphatase-1 facilitate interaction of the phosphatase
with enzymes of glycogen metabolism. We have shown that overexpression of one member of
the family, protein targeting to glycogen (PTG), causes large increases in glycogen ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] CG Armstrong, MJ Doherty, PT Cohen - Biochemical Journal, 1998 - pubmedcentral.nih.gov Deletion and mutational analyses of the rat liver glycogen- targeting subunit (G L ) of protein
phosphatase 1 (PP1) have identified three separate domains that are responsible for binding
of PP1, glycogen and phosphorylase a. The glycogen-binding domain spans the centre of ... Cited by 50 - Related articles - BL Direct - All 7 versions
- ►jbc.org C Lerin, E Montell, HK Berman, CB Newgard, AM … - Journal of Biological …, 2000 - ASBMB There is growing evidence that glycogen targeting subunits of protein phosphatase-1 play a
critical role in regulation of glycogen metabolism. In the current study, we have investigated the
effects of adenovirus-mediated overexpression of a specific glycogen targeting subunit ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org M Delibegovic, CG Armstrong, L Dobbie, PW Watt, AJH … - Diabetes, 2003 - Am Diabetes Assoc Disruption of the PPP1R3A gene encoding the glycogen targeting subunit (G M /R GL ) of protein
phosphatase 1 (PP1) causes substantial lowering of the glycogen synthase activity and a
10-fold decrease in the glycogen levels in skeletal muscle. Homozygous G M −/− mice ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►jbc.org NM Fong, TC Jensen, AS Shah, NN Parekh, AR … - Journal of Biological …, 2000 - ASBMB The activation of protein phosphastase-1 (PP1) by insulin plays a critical role in the regulation
of glycogen metabolism. PTG is a PP1 glycogen-targeting protein, which also binds the PP1
substrates glycogen synthase, glycogen phosphorylase, and phosphorylase kinase ... Cited by 33 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] GJ Browne, M Delibegovic, S Keppens, W … - Biochemical …, 2001 - pubmedcentral.nih.gov Gareth J. BROWNE*1, Mirela DELIBEGOVIC*1, Stefaan KEPPENS†, Willy STALMANS† and
Patricia TW COHEN*2 *MRC Protein Phosphorylation Unit, School of Life Sciences, MSI/WTB
Complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK, and † ... Cited by 24 - Related articles - BL Direct - All 10 versions
- ►nih.gov SM Crosson, A Khan, J Printen, JE Pessin, … - Journal of Clinical …, 2003 - Am Soc Clin Investig Protein targeting to glycogen (PTG) is a scaffolding protein that targets protein phosphatase 1α
(PP1α) to glycogen, and links it to enzymes involved in glycogen synthesis and degradation.
We generated mice that possess a heterozygous deletion of the PTG gene. These mice ... Cited by 33 - Related articles - BL Direct - All 12 versions
IR Kelsall, S Munro, I Hallyburton, JL Treadway, PTW … - FEBS letters, 2007 - Elsevier The inhibition of hepatic glycogen-associated protein phosphatase-1 (PP1-G L ) by glycogen
phosphorylase a prevents the dephosphorylation and activation of glycogen synthase, suppressing
glycogen synthesis when glycogenolysis is activated. Here, we show that a peptide ( 280 ... Cited by 8 - Related articles - All 6 versions
