- ►diabetesjournals.org A Kupila, P Keskinen, T Simell, S Erkkilä, P Arvilommi, … - Diabetes, 2002 - Am Diabetes Assoc Timing of onset of autoimmunity is a prerequisite for unmasking triggers and pathogenesis of
type 1 diabetes. We followed 4,590 consecutive newborns with 8 or 3% HLA-DQB1 conferred
risk for type 1 diabetes at 3-, 6-, or 12-month intervals up to 5.5 years of age. Islet cell ... Cited by 41 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Knip - Diabetes care, 2002 - Am Diabetes Assoc Diabetes-associated autoantibodies have been shown to be useful in the assessment of diabetes
risk among first-degree relatives of subjects with type 1 diabetes (1–3), whereas their predictive
characteristics are poorly defined in the general population, from which ∼90% of the ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►endojournals.org [PDF] M Kukko… - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Abbreviated title: Dynamics of autoimmunity in young children ... M. KUKKO 1,2 , T. KIMPIMÄKI
1,2 , S. KORHONEN 1,3 , A. KUPILA 1,4 , S. SIMELL 1,4 , R. ... VEIJOLA 1,3 , T. SIMELL 1,4
, J. ILONEN 1,5 , O. SIMELL 1,4 , AND M. KNIP 1,2,6 ... 1 The JDRF Center for the ... Cited by 4 - Related articles
P Keskinen, S Korhonen, A Kupila, R Veijola, S Erkkilä, … - Diabetologia, 2002 - Springer Aims/hypothesis. A reduced first-phase insulin re- sponse to intravenous glucose is perceived
as a sign of far-advanced deterioration of beta-cell function during the development of Type I
(insulin-dependent) diabe- tes mellitus, but data on insulin responses at the onset of ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►direct-ms.org [PDF] O Vaarala, P Klemetti, S Juhela, O Simell, H Hyöty, J … - Diabetologia, 2002 - Springer Immunisation to insulin is associated with autoim- mune diabetes. In non-obese diabetic
(NOD) mice insulin-reactive T-cells infiltrate the islets and induce diabetes when transferred
to healthy recipients [1]. Insulin autoantibodies (IAA) appear often as the first autoantibody ... Cited by 31 - Related articles - BL Direct - All 6 versions
- ►endojournals.org J Yu, L Yu, TL Bugawan, HA Erlich, K Barriga, M … - Journal of Clinical …, 2000 - Endocrine Soc We hypothesized that genetic determinants of expression of persistent antiislet autoantibodies
would similarly influence the expression of transient autoantibodies. To test this hypothesis, we
prospectively evaluated sera from 478 relatives (SOC: sibling-offspring cohort) of patients ... Cited by 42 - Related articles - BL Direct - All 8 versions
- ►ispad.org [PDF] M Knip - Hormone research, 2000 - content.karger.com The clinical presentation of type 1 diabetes is preceded by an asymptomatic latent period characterized
by the presence of diabetes-associated autoantibodies in the peripheral circulation, reflecting
-cell damage. This prediabetic period may last for months and years. Several studies ... Cited by 40 - Related articles - BL Direct - All 10 versions
M Knip - Journal of endocrinological investigation, 2003 - ncbi.nlm.nih.gov 1: J Endocrinol Invest. 2003 Mar;26(3):265-7. Cow's milk and the new trials for
prevention of type 1 diabetes. Knip M. Hospital for Children and Adolescents, University
of Helsinki, Helsinki, Finland. mikael.knip@hus.fi. Mesh Terms ... Cited by 7 - Related articles - BL Direct - All 3 versions
[CITATION] Successful prospective prediction of type 1 diabetes in schoolchildren by multiple …
- ►endojournals.org T Kimpimaki, A Kupila, AM Hamalainen, M … - Journal of Clinical …, 2001 - Endocrine Soc Little is known about the timing of the etiological events and the preclinical process of type 1
diabetes during the first years of life in the general population. In this population-based prospective
birth cohort study, the appearance of diabetes-associated autoantibodies as a sign of ... Cited by 117 - Related articles - BL Direct - All 5 versions
