SA Hinke, RW Gelling, RA Pederson, S … - Diabetes, 2002 - Am Diabetes Assoc The therapeutic potential of glucose-dependent insulinotropic polypeptide (GIP)
for improving glycemic control has largely gone unstudied. A series of synthetic
GIP peptides modified at the NH 2 -terminus were screened in vitro for ... Cited by 57 - Related articles - BL Direct - All 6 versions
- ►endocrinology-journals.org [PDF] FP O'Harte, MH Mooney, CM Kelly, PR Flatt - Journal of Endocrinology, 2000 - Soc Endocrinology Gastric inhibitory polypeptide (GIP) is an important insulin-releasing hormone
of the enteroinsular axis which is rapidly inactivated by the exopeptidase
dipeptidyl peptidase (DPP) IV. The present study has examined the ability ... Cited by 42 - Related articles - BL Direct - All 10 versions
- ►endocrinology-journals.org [PDF] VA Gault, PR Flatt, P Harriott, MH Mooney, CJ … - Journal of Endocrinology, 2003 - Soc Endocrinology The therapeutic potential of glucagon-like peptide-1 (GLP-1) in improving
glycaemic control in diabetes has been widely studied, but the potential
beneficial effects of glucose-dependent insulinotropic polypeptide (GIP) ... Cited by 25 - Related articles - BL Direct - All 8 versions
- ►cyclicamp.ca [PDF] SA Hinke, S Manhart, N Pamir, HU Demuth, R … - Biochimica et Biophysica Acta (BBA)/Protein …, 2001 - Elsevier The incretins are a class of hormones released from the small bowel that act on
the endocrine pancreas to potentiate insulin secretion in a glucose-dependent
manner. Due to the requirement for an elevated glucose concentration for ... Cited by 31 - Related articles - All 3 versions
- ►diabetica.co.uk [PDF] VA Gault, PR Flatt, FPM O'Harte - Biochemical and Biophysical Research …, 2003 - Elsevier Glucose-dependent insulinotropic polypeptide (GIP) is a key incretin hormone,
released postprandially into the circulation in response to feeding, producing a
glucose-dependent stimulation of insulin secretion. It is this glucose- ... Cited by 55 - Related articles - All 7 versions
- ►cyclicamp.ca [PDF] K Kuhn-Wache, S Manhart, T Hoffmann, SA … - Advances in Experimental Medicine and Biology, 2000 - Springer The incretin GIF (glucose-dependent insulinotropic polypeptide), a 42 amino acid
peptide, is released from the K-cells of the small intestine into the blood in
response to oral nutrient ingestion. GIP inhibits the secretion of gastric ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] FP O'Harte, MH Mooney, PR Flatt - Diabetes, 1999 - Am Diabetes Assoc Gastric inhibitory polypeptide (GIP) is an important insulin-releasing hormone
of the enteroinsular axis that, like glucagon-like peptide 1(7-36) amide
(tGLP-1), has a functional profile of possible therapeutic value for type 2 ... Cited by 47 - Related articles - BL Direct - All 4 versions
[CITATION] Enhanced cyclic AMP generation and insulin-releasing potency of two novel N-terminal Tyr1- …
- ►endocrinology-journals.org [PDF] VA Gault, JC Parker, P Harriott, PR Flatt, FP O … - Journal of Endocrinology, 2002 - Soc Endocrinology The incretin hormone glucose-dependent insulinotropic polypeptide (GIP) is
rapidly degraded in the circulation by dipeptidyl peptidase IV forming the
N-terminally truncated peptide GIP(3–42). The present study exam- ined ... Cited by 57 - Related articles - BL Direct - All 5 versions
- ►diabetica.co.uk [PDF] VA Gault, N Irwin, P Harriott, PR Flatt, FPM O' … - Cell Biology International, 2003 - Elsevier Structure–function studies suggest that preservation of the N-terminus and
secondary structure of glucose-dependent insulinotropic polypeptide (GIP) is
important for biological activity. Therefore, a novel di-substituted ... Cited by 20 - Related articles - BL Direct - All 4 versions