P Bergsten, J Westerlund, P Liss, PO Carlsson - Diabetes, 2002 - Am Diabetes Assoc The role of metabolism in the generation of plasma insulin oscillations was investigated by simultaneous
in vivo recordings of oxygen tension (pO 2 ) in the endocrine and exocrine pancreas and portal
blood insulin concentrations in the anesthetized rat. At the start of the experiment, the ... Cited by 17 - Related articles - BL Direct - All 4 versions
GM Dahlgren, LM Kauri, RT Kennedy - BBA-General Subjects, 2005 - Elsevier Glucose induces complex patterns of oscillations in intracellular Ca 2+ concentration ([Ca 2+
] i ), metabolism and secretion in islets of Langerhans including “slow” and “fast” pulses with
period of 2–5 min and 10–20 s respectively. In an effort to elucidate the origin of slow ... Cited by 19 - Related articles - All 3 versions
CS Nunemaker, LS Satin - Endocrine, 2004 - Springer Received September 8, 2004; Revised September 23, 2004; Accepted September 24, 2004.
Author to whom all correspondence and reprint requests should be addressed: Dr. Leslie S.
Satin, Department of Pharmacology and Toxicology, Virginia Commonwealth University, ... Cited by 8 - Related articles - All 3 versions
PM Beigelman, B Ribalet - Diabetes, 1980 - Am Diabetes Assoc Glucose-induced beta-cell electrical activity, recorded with glass microelectrodes, is characterized
by trains of fast action potentials ("spikes"). The membrane depolarizes before each train of spikes
and then repolarizes. This pattern is termed a "burst." There is a characteristic biphasic ... Cited by 10 - Related articles - All 3 versions
CS Nunemaker, M Zhang, DH Wasserman, OP … - Diabetes, 2005 - Am Diabetes Assoc Pulsatile insulin secretion in vivo is believed to be derived, in part, from the intrinsic
glucose-dependent intracellular calcium concentration ([Ca 2+ ] i ) pulsatility of individual
islets. In isolation, islets display fast, slow, or mixtures of fast and slow [Ca 2+ ] i ... Cited by 24 - Related articles - BL Direct - All 10 versions
[CITATION] Glucose-induced mixed [Ca^ 2^+]~ c oscillations in mouse beta-cells are controlled …
- ►physiology.org SM Katzman, MA Messerli, DT Barry, A … - American Journal of …, 2004 - Am Physiological Soc The cells within the intact islet of Langerhans function as a metabolic syncytium, secreting insulin
in a coordinated and oscillatory manner in response to external fuel. With increased
glucose, the oscillatory amplitude is enhanced, leading to the hypothesis that cells within ... Cited by 7 - Related articles - BL Direct - All 4 versions
[CITATION] Correlated oscillations in glucose consumption, oxygen consumption, and …
- ►nih.gov R Bertram, L Satin, M Zhang, P Smolen, A Sherman - Biophysical journal, 2004 - Elsevier Pancreatic islets of Langerhans produce bursts of electrical activity when exposed to stimulatory
glucose levels. These bursts often have a regular repeating pattern, with a period of 10–60
s. In some cases, however, the bursts are episodic, clustered into bursts of bursts, which ... Cited by 46 - Related articles - BL Direct - All 15 versions
