CP Sewter, F Blows, A Vidal-Puig, SO'Rahilly - Diabetes, 2002 - Am Diabetes Assoc We have previously reported that omental (OM) preadipocytes respond less well to the prodifferentiating
effects of thiazolidinediones than do preadipocytes from subcutaneous (SC) depots. This finding
is consistent with in vivo alterations in fat distribution that occur in humans treated with ... Cited by 73 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] JP Frias, JG Yu, YT Kruszynska, JM Olefsky - Diabetes Care, 2000 - Am Diabetes Assoc Study subjects Nine type 2 diabetic, nine obese (BMI 26 kg/m2), and nine lean subjects (BMI
26 kg/m2) were studied. Clinical charac- teristics are given in Table 1. All were in good general
health and had normal re nal and liver function. Diabetic subjects were on oral ... Cited by 45 - Related articles - BL Direct - All 4 versions
TM Larsen, S Toubro, A Astrup - International journal of obesity, 2003 - nature.com The nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPAR ) is
a member of the PPAR family. The endogenous activators of all members of the PPAR family
are a variety of fatty acids, which suggests that the PPARs are highly involved in lipid ... Cited by 108 - Related articles - BL Direct - All 5 versions
MD Jensen - Annual review of nutrition, 1997 - Annual Reviews ▪ Abstract In vitro studies of adipocytes taken from different body fat regions suggest substantial
differences in lipolysis between intra-abdominal, lower-body subcutaneous, and abdominal subcutaneous
regions. Gender and obesity appear to influence these regional differences. In situ ... Cited by 83 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] IE Kelly, TS Han, K Walsh, ME Lean - Diabetes Care, 1999 - Am Diabetes Assoc Subjects and study design T he re were 16 male (aged 44–66 years) and 5 female (aged
49–74 years) patients with type 2 diabetes who were re c ru ited f rom the Diabetes Centre, Glasgow
Royal I n firm a ry. Subject selection was based on BMI of 40 kg/m2, which is below the ... Cited by 235 - Related articles - BL Direct - All 7 versions
JM Ye, N Dzamko, ME Cleasby, BD Hegarty, SM Furler, … - Diabetologia, 2004 - Springer Aims/hypothesis. Thiazolidinediones can enhance clearance of whole-body non-esterified fatty
acids and protect against the insulin resistance that develops during an acute lipid load. The
present study used [ 3 H]-R-bromopalmitate to compare the effects of the ... Cited by 72 - Related articles - BL Direct - All 4 versions
A Meirhaeghe, MWT Tanck, L Fajas, C Janot, N … - Molecular Genetics and …, 2005 - Elsevier Peroxisome proliferator-activated receptor-γ (PPARγ) plays a role in adipocyte differentiation
and insulin sensitization. We identified and characterized a new C/T substitution at position
−689 (−689C > T) in the P2 promoter of PPARγ in a putative GATA binding site. By ... Cited by 26 - Related articles - All 3 versions
- ►endojournals.org A Garg - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc It is well recognized that persons with generalized obesity suffer from a high risk of insulin resistance
and its metabolic complications, such as type 2 diabetes mellitus, hypertriglyceridemia, low levels
of high density lipoprotein cholesterol, hypertension, hepatic steatosis, hyperuricemia, ... Cited by 74 - Related articles - BL Direct - All 4 versions
- ►endojournals.org RK Semple, A Meirhaeghe, AJ Vidal-Puig, JWR … - Endocrinology, 2005 - Endocrine Soc Several missense mutations in the ligand-binding domain of human peroxisome
proliferator-activated receptor (PPAR) have been described in subjects with dominantly inherited
severe insulin resistance associated with partial lipodystrophy, hypertension, and ... Cited by 26 - Related articles - All 4 versions
