C Hernández-Sánchez, E Rubio, J Serna, EJ … - Diabetes, 2002 - Am Diabetes Assoc We have chosen a vertebrate model accessible during neurulation, the chick, for
analysis of endogenous insulin signaling and its contribution to early embryonic
cell survival. Unlike rodents, humans and chickens have a single ... Cited by 24 - Related articles - BL Direct - All 5 versions
C Hernández-Sánchez, A Mansilla, J Enrique, … - The EMBO Journal, 2003 - pubmedcentral.nih.gov Proinsulin is expressed prior to development of the pancreas and promotes cell
survival. Here we study the mechanism affecting the translation efficiency of a
specific embryonic proinsulin mRNA. This transcript shares the coding ... Cited by 34 - Related articles - BL Direct - All 8 versions
- ►endojournals.org AV Morales, J Serna, C Alarcon, EJ de la … - Endocrinology, 1997 - Endocrine Soc The characterization of (pro)insulin as an early embryonic growth factor
requires demonstration of its expression and cellular effects in vivo. By in
situ hybridization, we found widespread preproinsulin transcripts in the ... Cited by 35 - Related articles - BL Direct - All 3 versions
B Perez-Villamil, EJ De la Rosa, AV Morales, … - Endocrinology, 1994 - Endocrine Soc ABSTRACT Despite the absence of a pancreas, which develops between embry- onic
day 3 (E3) to E4, previous studies showed that insulin receptors are widely
expressed in chicken embryos from the blastoderm stage (unincubated embrvo. ... Cited by 32 - Related articles - BL Direct - All 3 versions
- ►pnas.org [PDF] AR Shuldiner, F De Pablo, CA Moore, J Roth - Proceedings of the National Academy of Sciences, 1991 - National Acad Sciences Page 1. Proc. Natl. Acad. Sci. USA Vol. 88, pp. 7679-7683, September 1991 Developmental
Biology Two nonallelic insulin genes in Xenopus laevis are expressed ... Cited by 31 - Related articles - All 8 versions
F Pablo, E Hernandez, F Collia, JA Gomez - Diabetologia, 1985 - Springer Summary. The teratogenic effect of insulin in early vertebrate embryos is
controversial and the mechanisms involved are un- known. We studied the effects
of pharmacological doses of in- sulin in chick embryos during the period of ... Cited by 19 - Related articles - All 3 versions
C Hernandez-Sanchez, A Mansilla, EJ de la … - Diabetologia, 2006 - Springer Abstract In postnatal organisms, insulin is well known as an essential anabolic
hormone responsible for maintaining glucose homeostasis. Its biosynthesis by the
pancreatic beta cell has been considered a model of tissue-specific gene ... Cited by 15 - Related articles - BL Direct - All 3 versions
F De Pablo, J Roth - Trends in biochemical sciences, 1990 - ncbi.nlm.nih.gov In the last decade, we witnessed the extension of endocrinologically based
concepts and molecules to many other arenas of intercellular communication, eg
immunology, hematology and cancer biology. At the start of the new decade ... Cited by 23 - Related articles - All 2 versions
- ►biologists.org [PDF] B Diaz, J Serna, F De Pablo, EJ de La Rosa - Development, 2000 - dev.biologists.org Programmed cell death is an important process in development (Jacobson et al.,
1997; Vaux and Korsmeyer, 1999). There have been many observations of the
process in the nervous system, including the initial description of ... Cited by 74 - Related articles - BL Direct - All 3 versions
