- ►diabetesjournals.org DK Sindelar, P Mystkowski, DJ Marsh, RD Palmiter, … - Diabetes, 2002 - Am Diabetes Assoc The combined effects of increased hypothalamic signaling by neuropeptide Y (NPY) and decreased
signaling by melanocortins are hypothesized to stimulate food intake when body fat stores are
depleted. To investigate NPY's role in the hyperphagic response to uncontrolled diabetes, ... Cited by 47 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] PJ Havel, TM Hahn, DK Sindelar, DG Baskin, MF … - Diabetes, 2000 - Am Diabetes Assoc Hypothalamic melanocortins are among several neu- ropeptides strongly implicated in the control
of food intake. Agonists for melanocortin 4 (MC-4) receptors such as -melanocyte–stimulating
hormone ( -MSH), a product of proopiomelanocortin (POMC), reduce food intake, ... Cited by 66 - Related articles - BL Direct - All 5 versions
T Kaga, A Inui, M Okita, A Asakawa, N Ueno, M Kasuga … - Diabetes, 2001 - Am Diabetes Assoc Neuropeptide Y (NPY), one of the most abundant peptide transmitters in the mammalian
brain, is assumed to play an important role in feeding and body weight regulation. However,
there is little genetic evidence that overexpression or knockout of the NPY gene leads to ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►physiology.org G Segal-Lieberman, DJ Trombly, V … - American Journal of …, 2003 - Am Physiological Soc Neuropeptide Y (NPY) is an orexigenic (appetite-stimulating) peptide that plays an important
role in regulating energy balance. When administered directly into the central nervous
system, animals exhibit an immediate increase in feeding behavior, and repetitive ... Cited by 36 - Related articles - BL Direct - All 4 versions
DK Sindelar, RD Palmiter, SC Woods, MW Schwartz - Peptides, 2005 - Elsevier Neuropeptide Y (NPY) is a potent orexigenic peptide that is implicated in the feeding response
to a variety of stimuli. The current studies employed mice lacking NPY (Npy−/−) and their
wild-type (Npy+/+) littermates to investigate the role of this peptide in the feeding ... Cited by 11 - Related articles - All 3 versions
SY Qu, YK Yang, JY Li, Q Zeng, I Gantz - Regulatory peptides, 2001 - cat.inist.fr To explore the role of agouti-related protein(AGRP) in diabetic hyperphagia changes in hypothalamic
AGRP mRNA levels were examined in diabetic rats. Rats rendered diabetic by streptozotocin
displayed marked hyperglycemia(blood glucose 456. 0 ± 8. 4 mg/dl versus 71. 8 ± 1. 9 ... Cited by 16 - Related articles - All 2 versions
- ►ebmonline.org MW Schwartz - Experimental Biology and Medicine, 2001 - SEBM Evidence has existed for more than 50 years in support of the hypothesis that body energy stored
in the form of fat is homeostatically regulated. Implicit in this concept is the existence of a biological
system that operates dynamically over time to match cumulative energy intake to energy ... Cited by 49 - Related articles - BL Direct - All 5 versions
PD Raposinho, DD Pierroz, P Broqua, RB White, T … - Molecular and Cellular …, 2001 - Elsevier Neuropeptide Y (NPY) is involved in the central regulation of appetite, sexual behavior, and reproductive
function. We have previously shown that chronic infusion of NPY into the lateral ventricle of normal
rats produced an obesity syndrome characterized by hyperphagia, hyperinsulinism and ... Cited by 76 - Related articles - All 4 versions
K McCrea, T Wisialowski, C Cabrele, B Church, A Beck … - Regulatory peptides, 2000 - cat.inist.fr Members of the neuropeptide Y(NPY) family regulate many physiological processes via interaction
with at least four functional, pharmacologically distinct Y-receptors. However, selective antagonists
developed for several subtypes have not been useful in defining particular Y-receptor ... Cited by 21 - Related articles - All 2 versions
