R Arya, J Blangero, K Williams, L Almasy, TD … - Diabetes, 2002 - Am Diabetes Assoc Insulin resistance syndrome (IRS)−related phenotypes, such as
hyperinsulinemia, obesity-related traits, impaired glucose tolerance,
dyslipidemia, and hypertension, tend to cluster into factors. We attempted ... Cited by 139 - Related articles - BL Direct - All 4 versions
- ►endojournals.org RJF Loos, PT Katzmarzyk, DC Rao, T Rice, AS … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc The metabolic syndrome involves multiple and interactive effects of genes and
environmental factors. To identify chromosomal regions encoding genes possibly
predisposing to the metabolic syndrome, we performed a genome-wide scan ... Cited by 62 - Related articles - BL Direct - All 4 versions
W Tang, MB Miller, SS Rich, KE North, JS … - Diabetes, 2003 - Am Diabetes Assoc Recent studies have demonstrated significant genetic and phenotypic correlation
underlying the clustering of traits involved in the multiple metabolic syndrome
(MMS). The aim of this study was to identify chromosomal regions ... Cited by 70 - Related articles - BL Direct - All 5 versions
KL Edwards, B Newman, E Mayer, JV Selby, … - Genetic epidemiology, 1997 - interscience.wiley.com The insulin resistance syndrome (IRS) is characterized by a combination of
interrelated coronary heart disease (CHD) risk factors, including low
high-density lipoprotein cholesterol (HDL-C) levels, obesity and increases ... Cited by 72 - Related articles - BL Direct - All 3 versions
- ►nih.gov R Duggirala, J Blangero, L Almasy, R Arya, TD … - The American Journal of Human Genetics, 2001 - Elsevier Insulin resistance and hyperinsulinemia are strong correlates of obesity and
type 2 diabetes, but little is known about their genetic determinants. Using
data on nondiabetics from Mexican American families and a multipoint ... Cited by 120 - Related articles - BL Direct - All 8 versions
- ►nih.gov MF Feitosa, IB Borecki, SS Rich, DK Arnett, … - The American Journal of Human Genetics, 2002 - Elsevier Obesity is a risk factor for many chronic diseases, including glucose
intolerance, lipid disorders, hypertension, and coronary heart disease. Even
though the body-mass index (BMI) is a heterogeneous phenotype reflecting ... Cited by 113 - Related articles - BL Direct - All 7 versions
M McQueen, L Bertram, E Rimm, D Blacker, S … - BMC genetics, 2003 - biomedcentral.com Because high blood pressure, altered lipid levels, obesity, and diabetes so
frequently occur together, they are sometimes collectively referred to as the
metabolic syndrome. While there have been many studies of each metabolic ... Cited by 46 - Related articles - Cached - All 8 versions
MA Austin, KL Edwards, MJ McNeely, WL … - Diabetes, 2004 - Am Diabetes Assoc A rapidly growing body of evidence demonstrates important associations between
the metabolic syndrome, characterized by a cluster of risk factors or phenotypes
that include dyslipidemia, central obesity, hypertension, and ... Cited by 50 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org BD Mitchell, CM Kammerer, MC Mahaney, J … - Arteriosclerosis, thrombosis, and vascular biology, 1996 - Am Heart Assoc Abstract Insulin resistance is part of a metabolic syndrome that also includes
non–insulin-dependent diabetes mellitus, dyslipidemia, obesity, and
hypertension. It has been hypothesized that insulin resistance represents ... Cited by 114 - Related articles - All 5 versions
- ►diabetesjournals.org CD Langefeld, LE Wagenknecht, JI Rotter, AH … - Diabetes, 2004 - Am Diabetes Assoc The metabolic syndrome is characterized by central obesity, dyslipidemia,
elevated blood pressure, and hyperglycemia. The Insulin Resistance
Atherosclerosis Study (IRAS) Family Study recruited extended pedigrees of ... Cited by 60 - Related articles - BL Direct - All 4 versions
