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Scholar Results 1 - 10 of about 101 related to Sentinelli: Human resistin gene, obesity, and type 2 diabetes. (0.09 sec) 

Human resistin gene, obesity, and type 2 diabetes


F Sentinelli, S Romeo, M Arca, E Filippi, F … - Diabetes, 2002 - Am Diabetes Assoc
The hormone resistin has been suggested to link obesity to type 2 diabetes by
modulating steps in the insulin-signaling pathway and inducing insulin
resistance. Thus, the resistin gene represents a potential candidate for ...
Cited by 110 - Related articles - BL Direct - All 4 versions

Systematic search for single nucleotide polymorphisms in the resistin gene


H Osawa, H Onuma, A Murakami, M Ochi, T … - Diabetes, 2002 - Am Diabetes Assoc
Resistin is a novel polypeptide specifically secreted from adipocytes, and its
serum levels are increased in obese diabetic mice. Resistin antagonizes insulin
and could account for insulin resistance. To determine whether there are ...
Cited by 117 - Related articles - BL Direct - All 4 versions

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians

- endojournals.org
X Ma, JH Warram, V Trischitta, A Doria - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
Resistin is a newly identified hormone secreted by adipocytes that inhibits
insulin action on peripheral tissues. The aim of our study was to investigate
whether genetic variability at this locus is associated with the risk of ...
Cited by 72 - Related articles - BL Direct - All 4 versions

Human resistin gene: molecular scanning and evaluation of association with insulin …

- endojournals.org
H Wang, WS Chu, C Hemphill, SC Elbein - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
Insulin resistance is strongly associated with obesity, but even among obese
subjects insulin sensitivity varies widely. Recently, a new adipocyte hormone,
resistin, was identified, shown to reduce insulin-mediated glucose uptake, ...
Cited by 136 - Related articles - BL Direct - All 4 versions

5′ flanking variants of resistin are associated with obesity


JC Engert, MC Vohl, SM Williams, P Lepage, JC … - Diabetes, 2002 - Am Diabetes Assoc
Diabetes and obesity have long been known to be related. The recently
characterized adipocyte hormone resistin (also called FIZZ3/ADSF) has been
implicated as a molecular link between impaired glucose tolerance (IGT) and ...
Cited by 146 - Related articles - BL Direct - All 4 versions

An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a …

- endojournals.org
A Pizzuti, A Argiolas, R Di Paola, R Baratta, A … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
Resistin is overexpressed in human adipose tissue of obese individuals and is
likely to modulate insulin sensitivity. Resistin is, therefore, a candidate gene
for insulin resistance. We searched for polymorphisms in the resistin gene ...
Cited by 63 - Related articles - BL Direct - All 4 versions

Association of resistin gene 3'-untranslated region+ 62G-> A polymorphism with type 2 …

- endojournals.org
MS Tan, SY Chang, DM Chang, JCR Tsai, YJ … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Resistin, a recently discovered polypeptide, antagonizes insulin action and may
play a part in the pathogenesis of insulin resistance. This study investigates
whether resistin gene polymorphism can be associated with type 2 diabetes. ...
Cited by 56 - Related articles - BL Direct - All 5 versions

Single nucleotide polymorphisms of the resistin (RSTN) gene


H Cao, RA Hegele - Journal of Human Genetics, 2001 - Springer
Abstract Type 2 diabetes mellitus is a complex phenotype that is frequently
associated with central obesity and insulin resistance. Recently, a protein
named resistin, encoded by RSTN (OMIM #605565), was identified in adipose ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Insulin resistance and type 2 diabetes are not related to resistin expression in human fat …


I Nagaev, U Smith - Biochemical and Biophysical Research …, 2001 - Elsevier
Resistin is secreted by rodent fat cells and was recently postulated to be an
important link between obesity and insulin resistance. We examined Resistin gene
expression with real-time RT-PCR in human isolated fat cells, adipose ...
Cited by 381 - Related articles - BL Direct - All 5 versions

Suppressed gene expression of adipocyte resistin in an insulin-resistant rat model probably …


CC Juan, LC Au, VS Fang, SF Kang, YH Ko, … - Biochemical and Biophysical research communications, 2001 - Elsevier
Resistin, the peptide specifically secreted from adipocytes, is a hormone
antagonistic to insulin action and, thus, may serve as a link between human
obesity due to adiposity and insulin resistance associated with type 2 ...
Cited by 156 - Related articles - BL Direct - All 7 versions


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