R Sinha, S Dufour, KF Petersen, V LeBon, S … - Diabetes, 2002 - Am Diabetes Assoc The metabolism and composition of skeletal muscle tissue is of special interest
because it is a primary site of insulin action and plays a key role in the
pathogenesis of insulin resistance. Intramyocellular (IMCL) triglyceride ... Cited by 189 - Related articles - BL Direct - All 5 versions
C Adiposity - Diabetes, 2002 - Am Diabetes Assoc Page 1. Assessment of Skeletal Muscle Triglyceride Content by 1 H Nuclear Magnetic
Resonance Spectroscopy in Lean and Obese Adolescents ... Related articles - All 3 versions
S Jacob, J Machann, K Rett, K Brechtel, A … - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc Insulin resistance plays an important role in the patho- genesis of type 2
diabetes; however, the multiple mech- anisms causing insulin resistance are not
yet fully understood. The aim of this study was to explore the pos- sible ... Cited by 361 - Related articles - BL Direct - All 4 versions
- ►endojournals.org C Thamer, J Machann, O Bachmann, M Haap, D … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc The existence of metabolically relevant intramyocellular lipids (IMCL) as
assessed by the noninvasive 1 H-magnetic resonance spectroscopy (MRS) has been
established. In the present studies, we analyzed the relationships between ... Cited by 101 - Related articles - BL Direct - All 4 versions
- ►physiology.org JH Hwang, JW Pan, S Heydari, HP … - Journal of Applied Physiology, 2001 - Am Physiological Soc Regional differences in the content of intramyocellular lipids (IMCL),
extramyocellular lipids, and total creatine (TCr) were quantified in soleus (S),
tibialis posterior (TP), and tibialis anterior (TA) muscles in humans using ... Cited by 89 - Related articles - BL Direct - All 4 versions
A Virkamäki, E Korsheninnikova, A Seppälä- … - Diabetes, 2001 - Am Diabetes Assoc To examine whether and how intramyocellular lipid (IMCL) content contributes to
interindividual variation in insulin action, we studied 20 healthy men with no
family history of type 2 diabetes. IMCL was measured as the resonance of ... Cited by 147 - Related articles - BL Direct - All 6 versions
M Krssak, K Falk Petersen, A Dresner, L … - Diabetologia, 1999 - Springer Skeletal muscle insulin resistance is a common fea- ture of obesity,
dyslipidaemia and arterial hyperten- sion, and it is an important predisposing
factor for Type II (non-insulin-dependent) diabetes mellitus and premature ... Cited by 556 - Related articles - BL Direct - All 6 versions
OP Bachmann, DB Dahl, K Brechtel, J Machann … - Diabetes, 2001 - Am Diabetes Assoc An increased intramyocellular lipid (IMCL) content, as quantified by 1
H-magnetic resonance spectroscopy ( 1 H-MRS), is associated with reduced insulin
sensitivity. At present, it is unclear which factors determine IMCL ... Cited by 158 - Related articles - BL Direct - All 5 versions
- ►endojournals.org BH Goodpaster, J He, S Watkins, DE Kelley - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc We examined the hypothesis that an excess accumulation of intramuscular lipid
(IMCL) is associated with insulin resistance and that this may be mediated by
the oxidative capacity of muscle. Nine sedentary lean (L) and 11 obese (O) ... Cited by 296 - Related articles - BL Direct - All 5 versions
C Boesch, J Slotboom, H Hoppeler, R Kreis - Magnetic Resonance in Medicine, 1997 - interscience.wiley.com Intra-myocellular lipids (IMCL) are stored in droplets in the cytoplasm of
muscle cells and are an energy storage form readily accessed during long-term
exercise. 1 H-MR spectroscopy methods are presented for noninvasive ... Cited by 263 - Related articles - BL Direct - All 3 versions
