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Scholar Results 1 - 10 of about 101 related to Sewter: Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform.... (0.13 sec) 

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform …


C Sewter, D Berger, RV Considine, G Medina, J … - Diabetes, 2002 - Am Diabetes Assoc
Sterol regulatory element binding protein (SREBP)-1 is a transcription factor
with important roles in the control of fatty acid metabolism and adipogenesis.
Little information is available regarding the expression of this molecule ...
Cited by 85 - Related articles - BL Direct - All 5 versions

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin- …

- diabetesjournals.org
I Guillet-Deniau, V Mieulet, S Le Lay, Y Achouri, … - Diabetes, 2002 - Am Diabetes Assoc
Sterol regulatory element binding protein-1c (SREBP-1c) is a transcription
factor that mediates insulin effects on hepatic gene expression. It is itself
transcriptionally stimulated by insulin in hepatocytes. Here we show that ...
Cited by 62 - Related articles - BL Direct - All 5 versions

Regulation by insulin of gene expression in human skeletal muscle and adipose tissue

- diabetesjournals.org
PH Ducluzeau, N Perretti, M Laville, F … - Diabetes, 2001 - Am Diabetes Assoc
Defective regulation of gene expression may be involved in the pathogenesis of
type 2 diabetes. We have characterized the concerted regulation by insulin (3-h
hyperinsulinemic clamp) of the expression of 10 genes related to insulin ...
Cited by 150 - Related articles - BL Direct - All 5 versions

Genetic variants in human sterol regulatory element binding protein-1c in syndromes of …

- diabetesjournals.org
M Laudes, I Barroso, J Luan, MA Soos, G Yeo, … - Diabetes, 2004 - Am Diabetes Assoc
The transcription factor sterol regulatory element binding protein (SREBP)-1c is
intimately involved in the regulation of lipid and glucose metabolism. To
investigate whether mutations in this gene might contribute to insulin ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Sterol regulatory element binding protein 1c (SREBP-1c) expression in human obesity


M Kolehmainen, H Vidal, E Alhava, MIJ … - Obesity, 2001 - nature.com
Discussion: SREBP-1c mRNA expression was lower in omental adipose tissue than in
subcutaneous depots in obese subjects before weight loss. Furthermore, the
expression of SREBP-1c in obese subjects was clearly lower than in normal ...
Cited by 35 - Related articles - BL Direct - All 2 versions

Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation …

- nutrition.org
ME Bizeau, PS MacLean, GC Johnson, Y Wei - Journal of Nutrition, 2003 - Am Soc Nutrition
Sterol regulatory element binding protein-1c (SREBP-1c) is a transcription
factor that responds to nutritional status and regulates metabolic gene
expression in liver and adipose tissue. Although SREBP-1c RNA is expressed ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Sterol regulatory element binding proteins: relationship of adipose tissue gene expression …


H Oberkofler, N Fukushima, H Esterbauer, F … - BBA-Gene Structure and Expression, 2002 - Elsevier
Sterol regulatory element binding proteins (SREBPs) are transcription factors
that are involved in adipogenesis and regulate the expression of genes
controlling cholesterol and fatty acid biosynthesis. Animal experiments ...
Cited by 18 - Related articles - All 5 versions

Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol …


M Boizard, X Le Liepvre, P Lemarchand, F … - Journal of Biological Chemistry, 1998 - ASBMB
Elevated lipogenesis is a key determinant of exaggerated fat deposition in
adipose tissue of obese Zucker rats. We previously delineated a region in the
fatty-acid synthase promoter, which was responsible for obesity-related ...
Cited by 77 - Related articles - BL Direct - All 6 versions

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French …

- diabetesjournals.org
D Eberlé, K Clément, D Meyre, M Sahbatou, M … - Diabetes, 2004 - Am Diabetes Assoc
Sterol regulatory element–binding protein (SREBP)-1 transcription factors play
a central role in energy homeostasis by promoting glycolysis, lipogenesis, and
adipogenesis. The sterol regulatory element–binding protein gene ...
Cited by 53 - Related articles - BL Direct - All 4 versions

In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, …

- physiology.org
SR Commerford, L Peng, JJ Dube, RM O' … - … Journal of Physiology- Regulatory, Integrative and …, 2004 - Am Physiological Soc
Sterol regulatory element binding protein-1c (SREBP-1c), a transcription factor
that is important for mediating insulin effects on metabolic gene expression in
liver during the fasted-to-fed transition, is also expressed in skeletal ...
Cited by 26 - Related articles - BL Direct - All 4 versions


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