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Scholar Results 1 - 10 of about 101 related to Kurucz: Decreased expression of heat shock protein 72 in skeletal muscle of patients with.... (0.10 sec) 

Decreased expression of heat shock protein 72 in skeletal muscle of patients with …

- diabetesjournals.org
I Kurucz, Á Morva, A Vaag, KF Eriksson, X Huang, L … - Diabetes, 2002 - Am Diabetes Assoc
Oxidative stress has been ascribed a role in the pathogenesis of diabetes and its
complications, and stress proteins have been shown to protect organisms in vitro and in vivo
against oxidative stress. To study the putative role of one of the most abundant ...
Cited by 46 - Related articles - BL Direct - All 4 versions

HSP72 protects against obesity-induced insulin resistance

- nih.gov
J Chung, AK Nguyen, DC Henstridge, AG … - Proceedings of the …, 2008 - National Acad Sciences
Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72,
which correlates with reduced insulin sensitivity. Heat therapy, which activates HSP72, improves
clinical parameters in these patients. Activation of several inflammatory signaling proteins ...
Cited by 30 - Related articles - BL Direct - All 8 versions

Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic …


M Kurthy, T Mogyorosi, K Nagy, T … - ANNALS-NEW …, 2002 - interscience.wiley.com
Abstract: Bimoclomol (BML), a symptomatic antidiabetic agent, has been developed by Biorex
R & D Co. to treat diabetic neuropathy and retinopathy. BRX-220, an orally active member of
the BRX family, has been developed to treat diabetic complications and insulin resistance ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in …


CR Bruce, AL Carey, JA Hawley, MA Febbraio - Diabetes, 2003 - Am Diabetes Assoc
To examine whether genes associated with cellular defense against oxidative stress are associated
with insulin sensitivity, patients with type 2 diabetes (n = 7) and age-matched (n = 5) and young
(n = 9) control subjects underwent a euglycemic-hyperinsulinemic clamp for 120 min. ...
Cited by 87 - Related articles - BL Direct - All 4 versions

Exercise training modulates heat shock protein response in diabetic rats

- physiology.org
M Atalay, NKJ Oksala, DE Laaksonen, S … - Journal of Applied …, 2004 - Am Physiological Soc
Strenuous exercise induces oxidative stress and modification of intracellular proteins. Exercise
training, however, upregulates endogenous antioxidant defenses and heat shock protein
(HSP) expression. In diabetes, perturbations in the endogenous antioxidant and HSP ...
Cited by 58 - Related articles - BL Direct - All 7 versions

Hot-tub therapy for type 2 diabetes mellitus


PL Hooper - New England Journal of Medicine, 1999 - content.nejm.org
To the Editor: Physical exercise is effective therapy for patients with type 2 diabetes mellitus.
Therefore, my colleagues and I asked the following question: Would the effects of partial immersion
in a hot tub simulate the beneficial effects of exercise? We asked eight patients (five men ...
Cited by 24 - Related articles - All 5 versions

Diabetes, nitric oxide, and heat shock proteins

- diabetesjournals.org [PDF] 
PL Hooper - Diabetes care, 2003 - Am Diabetes Assoc
It is well known that hyperglycemia is associated with increased mortality from cardiovascular
disease (CVD) and all-cause mortality. It has recently been reported that subjects with low fasting
plasma glucose (FPG) levels also had a high risk of CVD and all-cause mortality (1). ...
Cited by 8 - Related articles - BL Direct - All 5 versions

The function of endogenous protective systems in patients with insulin-dependent …


IA Strokov, EB Manukhina, LY Bakhtina, IY … - Bulletin of experimental …, 2000 - Springer
IA Strokov, EB Manukhina,* L. Yu. Bakhtina, I. Yu. Malyshev,* GK Zoloev,** SI Kazikhanova, and
AS Ametov ... Translated from Byulleten Eksperimental noi Biologii i Meditsiny, Vol. 130, No.
10, pp. 437-441, October, 2000 Original article submitted September 18, 2000
Cited by 18 - Related articles - BL Direct - All 6 versions

Characteristic changes of stress protein expression in streptozotocin-induced …


N Yamagishi, K Nakayama, T Wakatsuki, T Hatayama - Life Sciences, 2001 - Elsevier
Content-length: 1367. ...
Cited by 22 - Related articles - All 3 versions

Loss of defense against stress: diabetes and heat shock proteins

- hspsanddiabetes.com [PDF] 
PL Hooper, JJ Hooper - Diabetes Technology & Therapeutics, 2005 - liebertonline.com
W E PROPOSE THAT DIABETES produces a vul- nerable condition with impaired de- fenses
against stress, resulting in widespread unprotected organ systems. More specifi- cally, the ultimate
natural history of diabetes and its complications is determined by the net effect of ...
Cited by 16 - Related articles - All 4 versions


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