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Scholar Results 1 - 10 of about 101 related to Sidell: Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in.... (0.16 sec) 

Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in …

- diabetesjournals.org
RJ Sidell, MA Cole, NJ Draper, M Desrois, RE … - Diabetes, 2002 - Am Diabetes Assoc
Obesity is associated with risk factors for cardiovascular disease, including insulin resistance,
and can lead to cardiac hypertrophy and congestive heart failure. Here, we used the
insulin-sensitizing agent ...
Cited by 101 - Related articles - BL Direct - All 6 versions

Age-dependent changes in metabolism, contractile function, and ischemic …

- diabetesjournals.org
E Aasum, AD Hafstad, DL Severson, TS Larsen - Diabetes, 2003 - Am Diabetes Assoc
Glucose and palmitate metabolism and contractile function were measured with ex vivo perfused
working hearts from control (db/+) and diabetic (db/db) female mice at 6, 10–12, and 16–18 weeks
of age. Palmitate oxidation was ...
Cited by 102 - Related articles - BL Direct - All 4 versions

In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome …

- ahajournals.org
T Yue, J Chen, W Bao, PK Narayanan, A Bril, W Jiang, … - Circulation, 2001 - Am Heart Assoc
Methods and Results Male Lewis rats were anesthetized, and the left anterior descending coronary
artery was ligated for 30 minutes. After reperfusion for 24 hours, the ischemic and infarct sizes
were determined. ROSI at 1 and 3 ...
Cited by 217 - Related articles - BL Direct - All 5 versions

Rosiglitazone, a peroxisome proliferator-activated receptor-γ, inhibits the Jun NH2- …

- diabetesjournals.org
N Khandoudi, P Delerive, I Berrebi-Bertrand, RE … - Diabetes, 2002 - Am Diabetes Assoc
This study was conducted to evaluate whether treatment of normal and diabetic rat hearts with
rosiglitazone, a high-affinity ligand of the peroxisome proliferator-activated receptor-γ (PPAR-γ)
used for the treatment of type 2 ...
Cited by 127 - Related articles - BL Direct - All 4 versions

Troglitazone improves recovery of left ventricular function after regional ischemia in …

- ahajournals.org
P Zhu, L Lu, Y Xu, GG Schwartz - Circulation, 2000 - Am Heart Assoc
Methods and Results—Juvenile pigs (n=6) were treated with troglitazone (75 mg · kg -1 · d -1 PO)
for 8 weeks. Untreated pigs (n=8) served as controls. Under anesthetized, open-chest conditions,
pigs underwent 90 minutes of ...
Cited by 79 - Related articles - BL Direct - All 5 versions

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db …

- physiology.org
DD Belke, TS Larsen, EM Gibbs, DL … - American Journal of …, 2000 - Am Physiological Soc
Contractile function and substrate metabolism were characterized in perfused hearts from genetically
diabetic C57BL/KsJ-lepr db /lepr db (db/db) mice and their non-diabetic lean littermates.
Contractility was assessed in ...
Cited by 184 - Related articles - BL Direct - All 3 versions

Treatment of type 2 diabetic db/db mice with a novel PPAR {gamma} agonist …

- physiology.org
AN Carley, LM Semeniuk, Y Shimoni, E … - American Journal of …, 2004 - Am Physiological Soc
Hearts from insulin-resistant type 2 diabetic db/db mice exhibit features of a diabetic
cardiomyopathy with altered metabolism of exogenous substrates and reduced contractile performance.
Therefore, the effect of chronic ...
Cited by 59 - Related articles - BL Direct - All 5 versions

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM …

- physiology.org
E Aasum, DD Belke, DL Severson, RA … - American Journal of …, 2002 - Am Physiological Soc
Hearts from diabetic db/db mice, a model of Type 2 diabetes, exhibit left ventricular failure and
altered metabolism of exogenous substrates. Peroxisome proliferator-activated receptor- (PPAR- )
ligands reduce plasma lipid and ...
Cited by 90 - Related articles - BL Direct - All 6 versions

Rosiglitazone treatment in Zucker diabetic fatty rats is associated with ameliorated …


TL Yue, W Bao, JL Gu, J Cui, L Tao, XL Ma, EH … - Diabetes, 2005 - Am Diabetes Assoc
The mechanism responsible for the enhanced myocardial susceptibility to ischemic insult in patients
with type 2 diabetes is not clear. The present study examines the effect of rosiglitazone treatment
on cardiac insulin sensitization ...
Cited by 76 - Related articles - All 6 versions

Cardiac carbohydrate metabolism in Zucker diabetic fatty rats

- oxfordjournals.org
JC Chatham, AML Seymour - Cardiovascular research, 2002 - cardiovascres.oxfordjournals.org
Diabetes is linked to obesity, dyslipidemia and hypertension [1–3], which are associated with
increased risk for coronary artery disease, cardiac hypertrophy and heart failure [3–5]. However,
there is growing evidence to ...
Cited by 46 - Related articles - All 8 versions


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