Y Mori, S Otabe, C Dina, K Yasuda, C Populaire, C … - Diabetes, 2002 - Am Diabetes Assoc The genetic background that predisposes the Japanese population to type 2 diabetes is largely
unknown. Therefore, we conducted a 10-cM genome-wide scan for type 2 diabetes traits in the
359 affected individuals from 159 families, yielding 224 affected sib-pairs of Japanese ... Cited by 166 - Related articles - BL Direct - All 4 versions
TH Luo, Y Zhao, G Li, WT Yuan, JJ Zhao, JL Chen, W … - Diabetologia, 2001 - Springer Type II (non-insulin-dependent) diabetes mellitus is a major health problem in many developed
countries. In developing countries, like China, the prevalence of Type II diabetes has statistically
significantly in- creased in recent years, especially along with eco- nomic growth. In ... Cited by 116 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org MA Permutt, JC Wasson, BK Suarez, J Lin, J Thomas, J … - Diabetes, 2001 - Am Diabetes Assoc A total of 896 individuals of Ashkenazi Jewish descent were ascertained in Israel from 267 multiplex
families, including 472 sib-pairs affected with type 2 diabetes. A genome-wide scan with average
marker spacing of 9.5 cM revealed five regions on four chromosomes (4q, 8q, 14q, and ... Cited by 123 - Related articles - BL Direct - All 4 versions
- ►nih.gov CM Lindgren, MM Mahtani, E Widen, MI McCarthy, … - The American Journal of …, 2002 - Elsevier Type 2 diabetes mellitus is a heterogeneous inherited disorder characterized by chronic hyperglycemia
resulting from pancreatic β-cell dysfunction and insulin resistance. Although the pathogenic mechanisms
are not fully understood, manifestation of the disease most likely requires interaction ... Cited by 117 - Related articles - BL Direct - All 9 versions
N Vionnet, EH Hani, S Dupont, S Gallina, S … - American journal of …, 2000 - ncbi.nlm.nih.gov Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a
novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent
replication of a type 2-diabetes locus on chromosome 1q21-q24. ... Vionnet N, Hani EH, ... Cited by 437 - Related articles - BL Direct - All 4 versions
- ►nih.gov F Busfield, DL Duffy, JB Kesting, SM Walker, PK … - The American Journal of …, 2002 - Elsevier The prevalence of type 2 diabetes among Australian residents is 7.5%; however, prevalence
rates up to six times higher have been reported for indigenous Australian communities. Epidemiological
evidence implicates genetic factors in the susceptibility of indigenous Australians to type ... Cited by 59 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] T Klupa, MT Malecki, M Pezzolesi, L Ji, S Curtis, CD … - Diabetes, 2000 - Am Diabetes Assoc We previously reported suggestive linkage between type 2 diabetes and markers in a region
on chromo- some 20q using data from a collection of 29 Caucasian families in which type 2 diabetes
with middle-age–onset was segregated as an autosomal-dominant disorder. To map ... Cited by 80 - Related articles - BL Direct - All 7 versions
- ►nih.gov S Ghosh, RM Watanabe, TT Valle, ER Hauser, VL … - The American Journal of …, 2000 - Elsevier We performed a genome scan at an average resolution of 8 cM in 719 Finnish sib pairs with
type 2 diabetes. Our strongest results are for chromosome 20, where we observe a weighted
maximum LOD score (MLS) of 2.15 at map position 69.5 cM from pter and secondary ... Cited by 221 - Related articles - BL Direct - All 4 versions
S Ghosh, RM Watanabe, ER Hauser, T … - Proceedings of the …, 1999 - National Acad Sciences We are conducting a genome scan at an average resolution of 10 centimorgans (cM) for type
2 diabetes susceptibility genes in 716 affected sib pairs from 477 Finnish families. To date, our
best evidence for linkage is on chromosome 20 with potentially separable peaks located ... Cited by 202 - Related articles - BL Direct - All 8 versions