M Gaster, I Petersen, K Højlund, P Poulsen, … - Diabetes, 2002 - Am Diabetes Assoc The most well-described defect in the pathophysiology of type 2 diabetes is
reduced insulin-mediated glycogen synthesis in skeletal muscles. It is unclear
whether this defect is primary or acquired secondary to dyslipidemia, ... Cited by 50 - Related articles - BL Direct - All 4 versions
M Gaster, SR Kristensen, H Beck-Nielsen, HD … - Apmis, 2001 - interscience.wiley.com The aim of this study was to select an effective and stable protocol for the
differentiation of human satellite cells (Sc) and to identify the optimal time
period for the experimental use of differentiated human Sc-cultures. In ... Cited by 33 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] RR Henry, TP Ciaraldi, L Abrams-Carter, S … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov The Journal of Clinical Investigation Volume 98, Number 5, September 1996,
1231–1236 ... Glycogen Synthase Activity is Reduced in Cultured Skeletal
Muscle Cells of Non–Insulin-dependent Diabetes Mellitus Subjects ... Cited by 91 - Related articles - BL Direct - All 6 versions
M Gaster, HD Schrøder, A Handberg, H Beck- … - BBA-Molecular Basis of Disease, 2001 - Elsevier There is no consensus regarding the results from in vivo and in vitro studies on
the impact of chronic high insulin and/or high glucose exposure on acute insulin
stimulation of glycogen synthase (GS) kinetic parameters in human skeletal ... Cited by 18 - Related articles - All 4 versions
- ►diabetesjournals.org M Gaster, AC Rustan, V Aas, H Beck-Nielsen - Diabetes, 2004 - Am Diabetes Assoc Insulin resistance in skeletal muscle in vivo is associated with reduced lipid
oxidation and lipid accumulation. It is still uncertain whether changes in lipid
metabolism represent an adaptive compensation at the cellular level or a ... Cited by 52 - Related articles - BL Direct - All 4 versions
M Gaster, H Beck-Nielsen - BBA-Molecular Basis of Disease, 2004 - Elsevier Several defects in response to insulin have been described in vivo and in vitro
in type 2 diabetes: a decreased glucose transport, defective glucose oxidation
and altered glycogen synthesis. At present, it is unknown whether glucose ... Cited by 14 - Related articles - All 3 versions
GS Activity - DIABETES, 2002 - Am Diabetes Assoc The most well-described defect in the pathophysiology of type 2 diabetes is
reduced insulin-mediated glycogen synthesis in skeletal muscles. It is unclear
whether this defect is primary or acquired secondary to dyslipidemia, ... Related articles
- ►endojournals.org SE Nikoulina, TP Ciaraldi, L Carter, S … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Insulin signaling pathways potentially involved in regulation of skeletal muscle
glycogen synthase were compared in differentiated human muscle cell cultures
from nondiabetic and type 2 diabetic patients. Insulin stimulation of ... Cited by 33 - Related articles - BL Direct - All 4 versions
RR Henry, L Abrams, S Nikoulina, TP Ciaraldi - Diabetes, 1995 - Am Diabetes Assoc Myoblasts from human skeletal muscle were isolated from needle biopsy samples of
vastus lateralis and fused to differentiated multinucleated myotubes. Specific
high-affinity insulin and insulin-like growth factor I (IGF-I) binding, ... Cited by 127 - Related articles - BL Direct - All 4 versions
N Ørtenblad, M Mogensen, I Petersen, K … - BBA-Molecular Basis of Disease, 2005 - Elsevier In myotubes established from patients with type 2 diabetes (T2D), lipid
oxidation and insulin-mediated glucose oxidation are reduced, whereas in
myotubes from obese non-diabetic subjects, exposure to palmitate impairs ... Cited by 17 - Related articles - All 3 versions
