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Scholar Results 1 - 10 of about 101 related to Greenbaum: Impaired β-cell function, incretin effect, and glucagon suppression in patients.... (0.20 sec) 

Impaired β-cell function, incretin effect, and glucagon suppression in patients with type 1 …


CJ Greenbaum, RL Prigeon, DA D'Alessio - Diabetes, 2002 - Am Diabetes Assoc
We have recently described a novel phenotype in a group of subjects with type 1
diabetes that is manifested by glucose >11.1 mmol/l 120 min after an oral
glucose load, but with normal fasting glucose levels. We now describe the ...
Cited by 43 - Related articles - BL Direct - All 8 versions

Impact of lack of suppression of glucagon on glucose tolerance in humans

- physiology.org
P Shah, A Basu, R Basu, R Rizza - American Journal of Physiology- Endocrinology And …, 1999 - Am Physiological Soc
People with type 2 diabetes have defects in both - and -cell function. To
determine whether lack of suppression of glucagon causes hyperglycemia when
insulin secretion is impaired but not when insulin secretion is intact, ...
Cited by 55 - Related articles - BL Direct - All 3 versions

Immunoneutralization of somatostatin, insulin, and glucagon causes alterations in islet cell …


FC Brunicardi, R Kleinman, S Moldovan, THL … - Pancreas, 2001 - journals.lww.com
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston,
Texas; *Departments of Surgery and Medicine, UCLA School of Medicine, Los
Angeles, California; and †Linco Research, Inc., St. Charles, Missouri, USA
Cited by 21 - Related articles - BL Direct - All 4 versions

Glucagon-like peptide 1 improved glycemic control in type 1 diabetes


MT Behme, J Dupré, TJ McDonald - BMC Endocrine Disorders, 2003 - biomedcentral.com
Dose-finding studies were carried out to establish mid range doses for delay of
gastric emptying indicated by postponement of pancreatic polypeptide responses
after meals. The selected dose of 0.63 micrograms/kg GLP-1 was administered ...
Cited by 30 - Related articles - Cached - All 7 versions

Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in …

- diabetesjournals.org
GS Meneilly, CHS McIntosh, RA Pederson, JF … - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—Plasma glucose was allowed to fall from a fasting level of ∼11
mmol/l to 5.3 mmol/l in each study and thereafter was held stable at that level.
Plasma insulin levels during both studies were ∼900 pmol/l. Plasma ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Modulation of somatostatin release by endogenous glucagon and insulin: physiological …


K Murakami, H Taniguchi, M Tamagawa, K … - Endocrinologia japonica, 1982 - ncbi.nlm.nih.gov
In order to understand the physiological role of endogenous insulin or glucagon
in somatostatin release, isolated rat pancreatic islets were treated with
antiinsulin or antiglucagon antiserum in the presence of physiological ...
Cited by 5 - Related articles

Islet cell hormonal responses to hypoglycemia after human islet transplantation for type 1 …

- shouxi.net
MR Rickels, MH Schutta, R Mueller, JF … - Diabetes, 2005 - Am Diabetes Assoc
Islet transplantation can eliminate severe hypoglycemic episodes in patients
with type 1 diabetes; however, whether intrahepatic islets respond appropriately
to hypoglycemia after transplantation has not been fully studied. We ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon …


R Burcelin, B Thorens - Diabetes, 2001 - Am Diabetes Assoc
GLUT2 −/− mice reexpressing GLUT1 or GLUT2 in their β-cells (RIPGLUT1 ×
GLUT2 −/− or RIPGLUT2 × GLUT2 −/− mice) have nearly normal
glucose-stimulated insulin secretion but show high glucagonemia in the fed ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Zinc-induced changes in ionic currents of clonal rat pancreatic β-cells: activation of ATP- …

- physoc.org
A Bloc, T Cens, H Cruz, Y Dunant - The Journal of Physiology, 2000 - Physiological Soc
The Zn 2+ -induced hyperpolarisation arose from a dose-dependent increase in a
voltage-independent K + conductance that was pharmacologically identified as an
ATP-sensitive K + (K ATP ) conductance. The effect was rapid in onset, ...
Cited by 28 - Related articles - BL Direct - All 6 versions

Stimulatory effects of tolbutamide infusion on plasma glucagon in insulin-dependent diabetic …


NV BOHANNON, M LORENZI, GM GRODSKY … - Journal of Clinical Endocrinology & Metabolism, 1982 - Endocrine Soc
The effect of iv tolbutamide on endogenous glucagon levels was measured in nine
insulin-dependent diabetic patients chosen because they evidenced no C-peptide
response to β-cell secretagogues. Basal glucagon levels were not ...
Cited by 14 - Related articles - All 2 versions


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