- ►diabetesjournals.org JM Lin, ME Fabregat, R Gomis, P Bergsten - Diabetes, 2002 - Am Diabetes Assoc Plasma insulin in healthy subjects shows regular oscillations, which are
important for the hypoglycemic action of the hormone. In individuals with type 2
diabetes, these regular variations are altered, which has been implicated ... Cited by 24 - Related articles - BL Direct - All 5 versions
[CITATION] Functional and molecular alterations of pancreatic islets in human type 2 diabetes
P Marchetti, DW Scharp, M Mclear, R … - Diabetes, 1994 - Am Diabetes Assoc Insulin secretion from the pancreas is pulsatile. The precise site and function
of the pacemaker that regulates insulin periodicity in humans have not been
determined. We isolated human pancreatic islets from five cadaver organ ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►shouxi.net RA Ritzel, JJ Meier, CY Lin, JD Veldhuis, PC … - Diabetes, 2007 - Am Diabetes Assoc Insulin secretion from the 2,000–3,000 β-cells in an islet is a highly
synchronized activity with discharge of insulin in coordinate secretory bursts
at approximately 4-min intervals. Insulin secretion progressively declines ... Cited by 28 - Related articles - BL Direct - All 5 versions
CB Juhl, N Pørksen, SM Pincus, ÅP Hansen, … - Diabetes, 2001 - Am Diabetes Assoc The high-frequency oscillatory pattern of insulin release is disturbed in type 2
diabetes. Although sulfonylurea drugs are widely used for the treatment of this
disease, their effect on insulin release patterns is not well established. ... Cited by 20 - Related articles - BL Direct - All 4 versions
HK Nyblom, K Thorn, M Ahmed, P Bergsten - PROTEOMICS-Clinical Applications - interscience.wiley.com Extended hyperglycaemia leads to impaired glucose-stimulated insulin secretion
(GSIS) and eventually -cell apoptosis in individuals with type 2 diabetes
mellitus. In an attempt to dissect mechanisms behind the detrimental ... Cited by 11 - Related articles - BL Direct - All 4 versions
S Deng, M Vatamaniuk, X Huang, N Doliba, MM … - Diabetes, 2004 - Am Diabetes Assoc Type 2 diabetic subjects manifest both disordered insulin action and
abnormalities in their pancreatic islet cells. Whether the latter represents a
primary defect or is a consequence of the former is unknown. To examine the ... Cited by 95 - Related articles - BL Direct - All 4 versions
J Fernandez-Alvarez, I Conget, J Rasschaert, … - Diabetologia, 1994 - Springer Summary Islets were isolated by automatic digestion from non-diabetic cadaveric
organ donors and from Type 2 (non-insulin-dependent) diabetic subjects. The
activity of FAD-glycerophosphate dehydrogenase, but not that of either ... Cited by 48 - Related articles - BL Direct - All 4 versions
Y GUIOT, C SEMPOUX, P MOULIN, J … - Diabetes(New York, NY), 2001 - cat.inist.fr No decrease of the β-cell mass in type 2 diabetic patients. Yves GUIOT,
Christine SEMPOUX, Pierre MOULIN, Jacques RAHIER Diabetes ... Cited by 24 - Related articles - BL Direct - All 4 versions
- ►endojournals.org JM Lin, J Sternesjo, S Sandler, P Bergsten - Endocrinology, 1999 - Endocrine Soc During the development of type I diabetes, the plasma insulin pattern changes.
Because the islet secretory pattern has been implicated in this phenomenon,
insulin release was measured from female nonobese diabetic (NOD) mouse ... Cited by 5 - Related articles - BL Direct - All 4 versions
