- ►diabetesjournals.org L Günther, PO Berberat, M Haga, S Brouard, … - Diabetes, 2002 - Am Diabetes Assoc Pancreatic islets transplanted to treat autoimmune type 1 diabetes often fail to
function (primary nonfunction), likely because of islet β-cell apoptosis. We
show that carbon monoxide (CO), a product of heme oxygenase activity, ... Cited by 84 - Related articles - BL Direct - All 17 versions
A Nakao, K Kimizuka, DB Stolz, JS Neto, T … - Surgery, 2003 - Elsevier Background. Heme oxygenase (HO)-1 system has been shown to provide protection
against oxidative stress through the degradation of heme to biliverdin, free
iron, and carbon monoxide (CO). This study investigated cytoprotective ... Cited by 55 - Related articles - All 14 versions
- ►diabetesjournals.org H Wang, SS Lee, W Gao, E Czismadia, J … - Diabetes, 2005 - Am Diabetes Assoc Treatment of animals or certain cells with carbon monoxide (CO), a product of
heme degradation by heme oxygenase-1 (HO-1), has potent anti-inflammatory and
antiapoptotic effects that contribute to the survival of transplanted ... Cited by 35 - Related articles - All 6 versions
A Pileggi, RD Molano, T Berney, P Cattan, C … - Diabetes, 2001 - Am Diabetes Assoc Transplantation of islets of Langerhans represents a viable therapeutic approach
for the treatment of type 1 diabetes. Unfortunately, transplanted islets are
susceptible to allogeneic recognition and rejection, recurrence of ... Cited by 165 - Related articles - BL Direct - All 5 versions
T Fujita, K Toda, A Karimova, SF Yan, Y Naka, … - Nature Medicine, 2001 - nature.com Carbon monoxide (CO) can arrest cellular respiration, but paradoxically, it is
synthesized endogenously by heme oxygenase type 1 (Ho-1) in response to ischemic
stress. Ho-1−deficient (Hmox1 -/- ) mice exhibited lethal ischemic lung ... Cited by 276 - Related articles - BL Direct - All 2 versions
F Amersi, XD Shen, D Anselmo, J Melinek, S … - Hepatology, 2002 - interscience.wiley.com A direct role of carbon monoxide (CO), an effector-signaling molecule during
heme oxygenase-1 (HO-1) catalysis of heme, in the protection against hepatic
ischemia/reperfusion (I/R) injury needs to be established. This study was ... Cited by 137 - Related articles - BL Direct - All 4 versions
- ►physiology.org I Petrache, LE Otterbein, J Alam, GW … - American Journal of Physiology- Lung Cellular and …, 2000 - Am Physiological Soc Heme oxygenase (HO)-1 catalyzes the oxidative cleavage of heme to yield
equimolar amounts of biliverdin, iron, and carbon monoxide. HO-1 is a stress
response protein, the induction of which is associated with protection ... Cited by 200 - Related articles - BL Direct - All 3 versions
- ►amjpathol.org A Nakao, K Kimizuka, DB Stolz, JS Neto, T … - American Journal of Pathology, 2003 - ASIP Carbon monoxide (CO), a byproduct of heme catalysis by heme oxygenases, has been
shown to exert anti-inflammatory effects. This study examines the cytoprotective
efficacy of inhaled CO during intestinal cold ischemia/reperfusion injury ... Cited by 101 - Related articles - BL Direct - All 4 versions
E Tobiasch, L Günther, FH Bach - Journal of Investigative Medicine, 2001 - journals.lww.com Skip Navigation Links Home > November 2001 - Volume 49 - Issue 6 > Heme
Oxygenase-1 Protects Pancreatic [beta] Cells From Apopt... ... Tobiasch, Edda;
Günther, Lukas; Bach, Fritz H. ... From the Immunobiology Research ... Cited by 79 - Related articles - All 4 versions
- ►diabetesresearch.org [PDF] MM Ribeiro, D Klein, A Pileggi, R Damaris … - Biochemical and Biophysical Research …, 2003 - Elsevier Transplantation of islets is becoming an established method for treating type 1
diabetes. However, viability of islets is greatly affected by necrosis/apoptosis
induced by oxidative stress and other insults during isolation and ... Cited by 44 - Related articles - All 6 versions
