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Scholar Results 1 - 10 of about 101 related to Islam: The ryanodine receptor calcium channel of β-cells. (0.10 sec) 

The ryanodine receptor calcium channel of β-cells


M Islam… - Diabetes, 2002 - Am Diabetes Assoc
The list of Ca 2+ channels involved in stimulus-secretion coupling in β-cells
is increasing. In this respect the roles of the voltage-gated Ca 2+ channels and
IP 3 receptors are well accepted. There is a lack of consensus about the ...
Cited by 53 - Related articles - BL Direct - All 5 versions

Perspectives in Diabetes


M Regulation, P Significance - Diabetes, 2002 - Am Diabetes Assoc
P hysiological regulation of insulin secretion by glucose and incretin hormones
involves oscilla- tory changes in the cytosolic free Ca 2 concen- tration ([Ca 2
] c ) in -cells. The subcellular location, magnitude, and form of such [Ca ...
Related articles

Ryanodine receptors in human pancreatic β cells: localization and effects on insulin …

- fasebj.org [PDF] 
JD Johnson, S Kuang, S Misler, KS Polonsky - The FASEB Journal, 2004 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.03-1280fje. Published online
March 19, 2004. Ryanodine receptors in human pancreatic β cells: ...
Cited by 30 - Related articles - BL Direct - All 5 versions

[CITATION] Ca^ 2^+-induced Ca^ 2^+ release from the endoplasmic reticulum amplifies the Ca^ 2^+ …


R Lemmens, O Larsson, PO Berggren, MS … - Journal of Biological Chemistry, 2001 - WAVERLY PRESS INC
Cited by 34 - Related articles - BL Direct

Caffeine releases a glucose-primed endoplasmic reticulum Ca2+ pool in the insulin secreting …


A Gamberucci, R Fulceri, W Pralong, G … - FEBS letters, 1999 - Elsevier
Caffeine mobilized an intracellular Ca 2+ pool in intact fura-2-loaded INS-1
cells in suspension exposed to high (16 mM) [glucose], while a minor effect was
observed with low (2 mM) [glucose]. Cells were kept in a medium containing ...
Cited by 29 - Related articles - All 7 versions

Ca2+-induced Ca2+ release from the endoplasmic reticulum amplifies the Ca2+ signal …


R Lemmens, O Larsson, PO Berggren, M Islam … - Journal of Biological Chemistry, 2001 - ASBMB
Stimulus-secretion coupling in pancreatic β-cells involves membrane
depolarization and Ca 2+ entry through voltage-gated L-type Ca 2+ channels,
which is one determinant of increases in the cytoplasmic free Ca 2+ ...
Cited by 44 - Related articles - All 5 versions

Ryanodine receptors of pancreatic β-cells mediate a distinct context-dependent signal for …

- fasebj.org [PDF] 
JD Bruton, R Lemmens, CL Shi, S Persson- … - The FASEB Journal, 2002 - FASEB
*Department of Physiology, Karolinska Institutet, Stockholm, Sweden;
†Department of Molecular Medicine, Karolinska Institutet, Department of
Endocrinology, Karolinska Hospital, Stockholm, Sweden; flDepartment of ...
Cited by 35 - Related articles - BL Direct - All 5 versions

In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP- …

- pnas.org
M Islam… - Proceedings of the National Academy of Sciences, 1998 - National Acad Sciences
Molecular mechanisms that regulate in situ activation of ryanodine receptors
(RY) in different cells are poorly understood. Here we demonstrate that caffeine
(10 mM) released Ca 2+ from the endoplasmic reticulum (ER) in the form of ...
Cited by 90 - Related articles - BL Direct - All 10 versions

cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine …

- jbc.org
GG Holz, CA Leech, RS Heller, M Castonguay … - Journal of Biological Chemistry, 1999 - ASBMB
Glucagon-like peptide-1 (GLP-1) is an intestinally derived insulinotropic
hormone currently under investigation for use as a novel therapeutic agent in
the treatment of type 2 diabetes mellitus. In vitro studies of pancreatic ...
Cited by 114 - Related articles - BL Direct - All 4 versions

Dynamic imaging of endoplasmic reticulum Ca2+ concentration in insulin-secreting MIN6 …


A Varadi, GA Rutter - Diabetes, 2002 - ncbi.nlm.nih.gov
The endoplasmic reticulum (ER) plays a pivotal role in the regulation of
cytosolic Ca(2+) concentrations ([Ca(2+)](cyt)) and hence in insulin secretion
from pancreatic beta-cells. However, the molecular mechanisms involved in ...
Cited by 42 - Related articles - BL Direct - All 3 versions


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