- ►diabetesjournals.org H Ruan, N Hacohen, TR Golub, L Van Parijs, … - Diabetes, 2002 - Am Diabetes Assoc Tumor necrosis factor- (TNF- ) is a contributing cause of the insulin resistance
seen in obesity and obesity-linked type 2 diabetes, but the mechanism(s) by
which TNF- induces insulin resistance is not understood. By using 3T3-L1 ... Cited by 214 - Related articles - BL Direct - All 4 versions
H Ruan, PDG Miles, CM Ladd, K Ross, TR … - Diabetes, 2002 - Am Diabetes Assoc Despite extensive studies implicating tumor necrosis factor (TNF)-α as a
contributing cause of insulin resistance, the mechanism(s) by which TNF-α
alters energy metabolism in vivo and the tissue specificity of TNF-α ... Cited by 155 - Related articles - BL Direct - All 6 versions
SC Souza, HJ Palmer, YH Kang, MT Yamamoto, … - Journal of Cellular Biochemistry, 2003 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 69 - Related articles - BL Direct - All 3 versions
A Green, SB Dobias, DJ Walters, AR Brasier - Endocrinology, 1994 - Endocrine Soc ABSTRACT To investigate the effects of cytokines on adipocyte lipolysis, a
macrophage cell line (RAW 264.7) was treated with Escherichia coli
lipopolysaccharide (1 rg/ml) for 18 h to induce cytokine release. Con- ... Cited by 103 - Related articles - BL Direct - All 3 versions
- ►jbc.org H Xu, JK Sethi, GS Hotamisligil - Journal of Biological Chemistry, 1999 - ASBMB Tumor necrosis factor (TNF ) is a potent cytokine with multiple biological
activities and exists in two forms as follows: a 17-kDa soluble form that is a
cleaved product of the 26-kDa transmembrane form (mTNF ). It has been ... Cited by 75 - Related articles - BL Direct - All 5 versions
H Ruan, HF Lodish - Cytokine and Growth Factor Reviews, 2003 - Elsevier Insulin resistance is a fundamental defect that precedes the development of the
full insulin resistance syndrome as well as β cell failure and type 2 diabetes.
Tumor necrosis factor-α (TNF-α), a paracrine/autocrine factor highly ... Cited by 237 - Related articles - All 10 versions
- ►endojournals.org H Xing, JP Northrop, JR Grove, KE Kilpatrick, … - Endocrinology, 1997 - Endocrine Soc Tumor necrosis factor (TNF ) is a polypeptide hormone with pleiotropic effects
on cellular proliferation and differentiation. To investigate how TNF inhibits
and reverses adipocyte differentiation, we studied the expression of two ... Cited by 107 - Related articles - All 5 versions
- ►endocrinology-journals.org [PDF] P Peraldi, BM Spiegelman - Journal of Endocrinology, 1997 - Soc Endocrinology Insulin resistance is defined as a smaller than normal response to a given dose
of insulin. It is also a ubiquitous correlate of obesity and a central component
of non-insulin dependent diabetes mellitus. Insulin resistance causes a ... Cited by 13 - Related articles - BL Direct - All 6 versions
[CITATION] OBESITY AND THE ADIPOCYTE Studies of the mechanism of inhibition of insulin signaling by …
- ►endojournals.org JA Engelman, AH Berg, RY Lewis, MP Lisanti … - Molecular Endocrinology, 2000 - Endocrine Soc Tumor necrosis factor- (TNF ) has been implicated as a contributing mediator of
insulin resistance observed in pathophysiological conditions such as obesity,
cancer-induced cachexia, and bacterial infections. Previous studies have ... Cited by 76 - Related articles - BL Direct - All 4 versions
