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Scholar Results 1 - 10 of about 101 related to Pierroz: Effects of acute and chronic administration of the melanocortin agonist MTII in.... (0.11 sec) 

Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet …

- diabetesjournals.org
DD Pierroz, M Ziotopoulou, L Ungsunan, S … - Diabetes, 2002 - Am Diabetes Assoc
High-fat diet-induced obesity (DIO) in rodents is associated with
hyperleptinemia and resistance to leptin, but the response to agents acting
downstream of leptin receptors remains unknown. We assessed the response of ...
Cited by 102 - Related articles - BL Direct - All 5 versions

Responsiveness to peripherally administered melanocortins in lean and obese mice


S Blüher, M Ziotopoulou, JW Bullen, SJ … - Diabetes, 2004 - Am Diabetes Assoc
To elucidate mechanisms of melanocortin action, we investigated the effects of a
melanocortin receptor agonist (melanotetan II [MTII]) in lean C57BL/6J and obese
(DIO, ob/ob, UCP1-DTA) mice. MTII administration (100 μg qidip) for 24 h ...
Cited by 52 - Related articles - BL Direct - All 5 versions

The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more …

- endojournals.org
P Cettour-Rose, F Rohner-Jeanrenaud - Endocrinology, 2002 - Endocrine Soc
The effects of a 3-d peripheral administration of an -MSH agonist, MTII, on body
weight and the expression of uncoupling proteins (UCPs) and carnitine
palmitoyltransferase-1 were determined in lean and genetically obese fa/fa ...
Cited by 41 - Related articles - BL Direct - All 4 versions

Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced …

- endocrinology-journals.org [PDF] 
G Li, Y Zhang, JT Wilsey, PJ Scarpace - Journal of Endocrinology, 2004 - Soc Endocrinology
The effects of the chronic activation of the central melano- cortin (MC) system
by melanotan II (MTII) were assessed in chow-fed (CH) and high-fat (HF)
diet-induced obese (DIO) Sprague–Dawley rats. Six-day central infusion of ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Chronic application of MTII in a rat model of obesity results in sustained weight loss


BS Hamilton, HN Doods - Obesity, 2002 - nature.com
Research Methods and Procedures: Ex-breeder Chbb:Thom rats (350 to 400 g) were
divided into two groups: highly palatable food (HPF) and normal rat chow (RC).
Both groups had ab libitum access to rat chow. The HPF group had access to ...
Cited by 33 - Related articles - BL Direct - All 4 versions

Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity …

- diabetesjournals.org
G Li, CV Mobbs, PJ Scarpace - Diabetes, 2003 - Am Diabetes Assoc
Zucker (fa/fa) rats with defective leptin receptors are obese, hyperphagic, and
hyperinsulinemic. For testing whether chronic activation of the central
melanocortin pathway can bypass the defective leptin signaling and ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Central melanocortin system modulates energy intake and expenditure of obese and lean …

- physiology.org
JJ Hwa, L Ghibaudi, J Gao, EM Parker - … Journal of Physiology- Regulatory, Integrative and …, 2001 - Am Physiological Soc
Melanocortins play a critical role in appetite and body weight regulation,
because manipulations of this pathway can lead to the development of obesity in
several animal models. The purpose of this study was to use a melanocortin ...
Cited by 57 - Related articles - BL Direct - All 6 versions

Aged-obese rats exhibit robust responses to a melanocortin agonist and antagonist despite …


Y Zhang, M Matheny, N Tümer, PJ Scarpace - Neurobiology of aging, 2004 - Elsevier
To address whether defective melanocortin activation is one element of leptin
resistance with age, we infused centrally the melanocortin agonist, MTII and
antagonist, SHU9119 in young and old rats. Food intake, energy expenditure, ...
Cited by 27 - Related articles - All 9 versions

Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of …

- endojournals.org
DJ Clegg, SC Benoit, EL Air, A Jackman, P … - Endocrinology, 2003 - Endocrine Soc
The hypothalamic melanocortin (MC) system provides a critical inhibitory control
on food intake and body weight. Because access to high-fat (HF) diets is
associated with the development of obesity, we hypothesized that increased ...
Cited by 43 - Related articles - BL Direct - All 5 versions

Food conversion is transiently affected during 4-week chronic administration of melanocortin …

- endocrinology-journals.org [PDF] 
… , GV Skuladottir, H Watanobe, HB Schioth - Journal of Endocrinology, 2002 - Soc Endocrinology
The central melanocortin system is involved in the regu- lation of food intake
and body weight. In this study, we investigated the effect of a 4-week
intracerebroventricular infusion of the melanocortin receptor agonist MT-II ...
Cited by 30 - Related articles - BL Direct - All 5 versions


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