- ►diabetesjournals.org J Graham, WA Hagopian, I Kockum, LS Li, CB … - Diabetes, 2002 - Am Diabetes Assoc Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and
CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet
cells were determined by logistic regression analysis in 971 incident ... Cited by 72 - Related articles - BL Direct - All 6 versions
M Walter, E Albert, M Conrad, E Keller, M … - Diabetologia, 2003 - Springer Aim/hypothesis. Type 1 diabetes (T1D) is an autoim- mune disease with multiple
susceptibility genes. The aim of this study was to determine whether combining
IDDM1/HLA and IDDM2/insulin (INS) 5′ variable number of tandem repeat ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org C Pihoker, LK Gilliam, CS Hampe, Å … - Diabetes, 2005 - Am Diabetes Assoc Islet cell autoantibodies are strongly associated with the development of type 1
diabetes. The appearance of autoantibodies to one or several of the
autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►endojournals.org CS Hampe, LP Hammerle, L Bekris, E Ortqvist … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc Autoantibodies against the smaller isoform of glutamic acid decarboxylase (GAD)
are markers for Type 1 diabetes. GAD65 autoantibody (GAD65Ab)-positive
individuals in the general population are, however, mostly at low risk of ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►endojournals.org T Kimpimaki, P Kulmala, K Savola, A Kupila, S … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc The aim of this study was to evaluate the frequency and predictive value of
diabetes-associated autoantibodies, such as islet cell antibodies (ICA) and
autoantibodies to insulin (IAA), GAD65 (GADA), and the IA-2 molecule ... Cited by 71 - Related articles - BL Direct - All 5 versions
AR Mire-Sluis, R Gaines Das, Å Lernmark - Diabetologia, 2000 - Springer It has been known for two decades that patients with Type 1 (insulin-dependent)
diabetes mellitus develop autoantibodies to pancreatic islet cell antigens
[1±3] often many years before the clinical onset of the dis- ease. On ... Cited by 50 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] CS Hampe, I Kockum, M Landin-Olsson, C Torn … - Diabetes Care, 2002 - Am Diabetes Assoc The provision of diabetes care has shifted from the specialist to the generalist
in primary care practice. Evidence suggests utilization of nonphy- sician
providers in conjunction with phy- sician-directed protocols improves ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►nih.gov AL Notkins, A Lernmark - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig Type 1 diabetes, also known as either juvenile diabetes (because of the early
age of onset) or insulin-dependent diabetes mellitus (because of the clinical
need for insulin), is now widely thought to be an organ-specific autoimmune ... Cited by 156 - Related articles - BL Direct - All 9 versions
K Koczwara, E Bonifacio, AG Ziegler - Diabetes, 2004 - Am Diabetes Assoc It is suggested that the maternal transmission of islet autoantibodies increases
the risk of autoimmune diabetes in mice. The aim of this study was to determine
whether fetal exposure to islet autoantibodies modified the risk of type 1 ... Cited by 43 - Related articles - BL Direct - All 8 versions
CL Vandewalle, A Falorni, A Lernmark, P … - Diabetes Care, 1997 - Am Diabetes Assoc OBJECTIVE: To investigate the association of GAD (65-kDa) autoantibodies
(GAD65-Abs) and IA-2 autoantibodies (IA-2-Abs) with human leukocyte antigen
(HLA)-DQ and insulin gene (INS) risk markers in patients with recent-onset ... Cited by 44 - Related articles - All 5 versions
