G Matarese, V Sanna, RI Lechler, N Sarvetnick, S … - Diabetes, 2002 - Am Diabetes Assoc We have recently shown that leptin, the product of the obese gene, can directly influence T-cell
function. In the work presented here, we explored the role of leptin in the development of spontaneous
autoimmunity in the nonobese diabetic (NOD) mouse, an animal model for the study of ... Cited by 97 - Related articles - BL Direct - All 8 versions
- ►nih.gov [PDF] V Sanna, A Di Giacomo, A La Cava, RI … - Journal of Clinical …, 2003 - Am Soc Clin Investig In the work presented here, we explored the influence of leptin on the kinetics of experimental
autoimmune encephalomyelitis (EAE) onset, in the EAE-associated inflammatory anorexia, and
in the development of pathogenic T cell responses. We found that the expression of ... Cited by 145 - Related articles - BL Direct - All 10 versions
- ►jimmunol.org N Busso, A So, V Chobaz-Péclat, C Morard, … - The Journal of …, 2002 - Am Assoc Immnol Leptin is produced almost exclusively by adipocytes and regulates body weight at the hypothalamic
level. In addition, recent studies showed that leptin plays an important role in T lymphocyte
responses. To examine the role of leptin in Ag-induced arthritis, the development of joint ... Cited by 163 - Related articles - BL Direct - All 6 versions
LTFNODM Have, IT Responses - members.medscape.com NOD females show increased type 1 diabetes susceptibility compared with males [1,3] . We first
compared basal serum leptin levels (at 6 weeks of age) of NOD female mice with normal
age- and sex-matched females from other strains of mice that are not susceptible to type 1 ... Related articles
IS Hybridization, ELI Assay - members.medscape.com NOD/LtJ mice were purchased from The Jackson Laboratory (Bar Harbor, ME) and isolator-reared
at the Charles River Laboratories (Calco, Italy) before transfer to our animal facility, where they
were kept under specific pathogen-free conditions. Mice had free access to autoclaved ... Related articles
- ►jimmunol.org G Matarese, A Di Giacomo, V Sanna, GM … - The Journal of …, 2001 - Am Assoc Immnol Recent evidence indicates that leptin modifies T cell immunity, and may provide a key link between
nutritional deficiency and immune dysfunction. To study the influence of leptin on
autoimmunity, susceptibility to experimental autoimmune encephalomyelitis induced by ... Cited by 145 - Related articles - BL Direct - All 3 versions
G Matarese, V Sanna, AD Giacomo, GM … - European journal of …, 2001 - journals.pasteur.ac.ir SJL (H-2s) female mice are more susceptible than males to experimental autoimmune encephalomyelitis
(EAE) induced by immunization with myelin-derived peptides. The rea- sons for this sexual dimorphism
are unclear, but may include such factors as sex-related dif- ferences in immune ... Cited by 79 - Related articles - View as HTML - BL Direct - All 4 versions
DA Fraser, J Thoen, JE Reseland, Ø Førre, J Kjeldsen- … - Clinical rheumatology, 1999 - Springer Page 1. Original Article Decreased CD4+ Lymphocyte Activation and Increased Interleukin-4
Production in Peripheral Blood of Rheumatoid Arthritis Patients After Acute Starvation DA Fraser
1,2 , J. Thoen 1 , JE Reseland 3 , Ø. Førre 1 and J. Kjeldsen-Kragh 2 ... Cited by 61 - Related articles - BL Direct - All 3 versions
Z Tian, R Sun, H Wei, B Gao - Biochemical and biophysical research …, 2002 - Elsevier Leptin is an adipocyte-secreted hormone that centrally regulates weight control via targeting
the leptin receptor in the central nervous system. Recently, the leptin receptor has also been
detected in peripheral systems including immune tissues, suggesting that leptin may play ... Cited by 70 - Related articles - BL Direct - All 5 versions
B Siegmund*, HA Lehr, G Fantuzzi* - Gastroenterology, 2002 - Elsevier *1 Supported by the Broad Medical Foundation and the Deutsche Forschungsgemeinschaft DFG
SI 749/2-1 (to BS). Cited by 131 - Related articles - BL Direct - All 15 versions
