S Gregori, N Giarratana, S Smiroldo, M … - Diabetes, 2002 - Am Diabetes Assoc Type 1 diabetes is a chronic progressive autoimmune disease characterized by
mononuclear cell infiltration, dominated by interleukin-12 (IL-12)-dependent Th1
cells, of the pancreatic islets, with subsequent destruction of insulin- ... Cited by 185 - Related articles - BL Direct - All 5 versions
- ►direct-ms.org [PDF] S Gregori, N Giarratana, S Smiroldo, M … - Diabetes, 2002 - Am Diabetes Assoc From 1 BioXell, Milan, Italy; and the 2 Department of Oncology, Hoffmann-La
Roche, Nutley, New Jersey. Address correspondence and reprint requests to
Luciano Adorini, BioXell, Via Olgettina 58, I-20132 Milan, Italy. E-mail: ... Cited by 32 - Related articles - All 2 versions
- ►pnas.org MD Griffin, W Lutz, VA Phan, LA Bachman, … - Proceedings of the National Academy of Sciences, 2001 - National Acad Sciences Dendritic cells (DCs) play a central role in regulating immune activation and
responses to self. DC maturation is central to the outcome of antigen
presentation to T cells. Maturation of DCs is inhibited by physiological ... Cited by 225 - Related articles - BL Direct - All 6 versions
MD Griffin, WH Lutz, VA Phan, LA Bachman, … - Biochemical and Biophysical Research …, 2000 - Elsevier We show that the immunosuppressive effects of 1α,25-dihydroxyvitamin D 3
(1α,25(OH) 2 D 3 ) are due, in part, to inhibition of the T cell stimulatory
functions of dendritic cells (DCs). Addition of 10 −12 and 10 −8 M ... Cited by 114 - Related articles - BL Direct - All 6 versions
C Mathieu, M Waer, J Laureys, O Rutgeerts, R … - Diabetologia, 1994 - Springer Summary 1,25 dihydroxyvitamin D3, the active form of vitamin D, has
immunomodulatory properties in vitro and in vivo. We report that treatment with
1,25 dihy- droxyvitamin 03 (5 gg/kg on alternate days) prevents the ... Cited by 233 - Related articles - BL Direct - All 6 versions
C Mathieu, L Adorini - TRENDS in molecular medicine, 2002 - Elsevier The active form of vitamin D, 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ], is a
secosteroid hormone that regulates calcium and bone metabolism, controls cell
proliferation and differentiation, and exerts immunoregulatory activities. ... Cited by 222 - Related articles - All 8 versions
- ►jimmunol.org S Gregori, M Casorati, S Amuchastegui, S … - The Journal of Immunology, 2001 - Am Assoc Immnol 1 ,25-Dihydroxyvitamin D 3 , the active form of vitamin D 3 , and mycophenolate
mofetil, a selective inhibitor of T and B cell proliferation, modulate APC
function and induce dendritic cells (DCs) with a tolerogenic phenotype. ... Cited by 327 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org AGS van Halteren, E van Etten, EC de Jong, … - Diabetes, 2002 - Am Diabetes Assoc The active form of vitamin D 3 , 1α,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ),
is a potent immunomodulator known to affect T-cells through targeting
antigen-presenting cells such as dendritic cells (DCs). We studied the ... Cited by 68 - Related articles - BL Direct - All 8 versions
- ►jimmunol.org A Boonstra, FJ Barrat, C Crain, VL Heath, HFJ … - The Journal of Immunology, 2001 - Am Assoc Immnol 1 ,25-Dihydroxyvitamin D3 (vitD3) is an immunoregulatory hormone with beneficial
effects on Th1 mediated autoimmune diseases. Although the inhibitory effects of
vitD3 on macrophages and dendritic cells are well documented, any direct ... Cited by 188 - Related articles - BL Direct - All 2 versions
C Mathieu, M Waer, K Casteels, J Laureys, R … - Endocrinology, 1995 - Endocrine Soc Page 1. 0013-7227/95/$03.00/O Endocrinology Copyright 0 1995 by The Endocrine
Society Vol. 136, No. 3 Printed in USA Prevention of ... Cited by 92 - Related articles - BL Direct - All 6 versions
